Results 1 to 10 of about 100,521 (261)
S179D-human PRL, a pseudophosphorylated human PRL analog, is an agonist and not an antagonist [PDF]
Endocrinology, 2001 peer reviewedFor many years, our group has been involved in the development of human PRL antagonists. In two recent publications, S179D-human PRL, a human PRL analog designed to mimic a putative S179-phosphorylated human PRL, was reported to be a highly ...
Kelly, Paul A. +7 more
core +4 more sources
Expression and prognostic impact of the protein tyrosine phosphatases PRL-1, PRL-2, and PRL-3 in breast cancer [PDF]
British Journal of Cancer, 2006 The aim of this study was to investigate the expression of the protein tyrosine phosphatases (PTP) PRL-1, PRL-2, and PRL-3 in human breast cancer and to evaluate its clinical and prognostic significance. PRL-PTP mRNA expression was examined in malignant (n = 7) and nonmalignant (n = 7) cryoconserved breast tissue samples as well as in eight breast ...
Martin Gotte, L Kiesel, Gotte M
exaly +3 more sources
PRL PTPs: mediators and markers of cancer progression
Cancer and Metastasis Reviews, 2008 Aberrant protein tyrosine phosphorylation resulting from the altered activity of protein tyrosine phosphatases (PTPs) is increasingly being implicated in the genesis and progression of human cancer.
Catherine J Pallen
exaly +2 more sources
, 2023 Rebuttal submitted to Physical Review Letters to a reply by M. Oberlack & S. Hoyas (Apr. 2022) prior to their published Reply (Feb. 2023). The reply refers to the Comments [PRL 130, 069401 (2023)] and [PRL 130, 069402 (2023)]. All arguments put forth by
Frewer, Michael, Khujadze, George
core +2 more sources
Early effects of PRL on ion conductances in CHO cells expressing PRL receptor
American Journal of Physiology-Cell Physiology, 1994 Chinese hamster ovary (CHO-K1) cells were stably transfected with prolactin (PRL) receptor cDNA. These cells (CHO-E32) expressed the long form of functional PRL receptor.
R. Skryma +6 more
core +4 more sources
Bioorganic and Medicinal Chemistry Letters, 2012 Anthraquinones have been reported as phosphatase inhibitors. Therefore, anthraquinone derivatives were screened to identify a potent phosphatase inhibitor against the phosphatase of regenerating liver-3 (PRL-3).
Young-Min Han +2 more
exaly +2 more sources
PRL: A probabilistic relational language [PDF]
Machine Learning, 2006 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lise Getoor, John Grant
openaire +1 more source
, 2023 (A) Nanobody 19 pulls down 3XFLAG-PRL-3 with minimal to no pulldown of 3XFLAG-PRL-1 or 3XFLAG-PRL-2. Successful nanobody coupling to Dynabeads was verified using an antibody against the C-terminal 6XHis-tag present on each nanobody. (B) Nanobody 19 pulls
K. Martin Chow (772610) +7 more
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, 2023 (A) Phosphatase activity of PRL-3 alone or in complex with nanobody 91, against a generic diFMUP substrate. DiFMUP fluoresces when phosphate is released. The graph shows normalized fluorescence to PRL-3 alone, n = 12 ± standard deviation.
K. Martin Chow (772610) +7 more
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PRL-3 localization assessed by nanobody 26 and 19 is altered by N-terminal 3XFLAG and GFP tags.
, 2023 (A) Immunofluorescence of HCT116 cells transfected with CMV:3XFLAG-PRL-3, CMV:GFP-PRL-3, CMV:HA-PRL-3, or CMV-PRL-3, as indicated. Cells were stained with anti-PRL-3 nanobody 26 or 19 (HA) followed by an anti-alpaca VHH coupled to Alexa594 secondary ...
K. Martin Chow (772610) +7 more
core +1 more source