Results 1 to 10 of about 15,722 (184)

Evolution of the PRNT: Merging tradition and innovation to set the gold standard in the era of automation [PDF]

Human Vaccines and Immunotherapeutics
The plaque reduction neutralization test (PRNT) is the gold standard for quantifying neutralizing antibodies owing to its high sensitivity and specificity.
Adriana Souza Azevedo, Sheila Maria Barbosa de Lima, Fernando N Tavares   +2 more
exaly   +5 more sources

Plaque Reduction Neutralization Test (PRNT) Accuracy in Evaluating Humoral Immune Response to SARS-CoV-2

Diseases (Basel, Switzerland)
Massive vaccination positively impacted the SARS-CoV-2 pandemic, being a strategy to increase the titers of neutralizing antibodies (NAbs) in the population.
Ingrid Horbach, Waleska Dias Schwarcz, Brenda de Moura Dias   +2 more
exaly   +5 more sources

Is prnt a Pseudogene? Identification of Ram Prt in Testis and Ejaculated Spermatozoa

PLoS ONE, 2012
A hallmark of prion diseases or transmissible spongiform encephalopaties is the conversion of the cellular prion protein (PrP(C)), expressed by the prion gene (prnp), into an abnormally folded isoform (PrP(Sc)) with amyloid-like features that causes ...
Jorge Mbga Pimenta, Ana Domingos, Aldino Viegas   +2 more
exaly   +6 more sources

Comparison of measles plaque reduction neutralization test (PRNT) and measles virus-specific IgG ELISA for assessment of immunogenicity of measles-mumps-rubella vaccination at 5–7 months of age and maternal measles antibodies

Vaccine: X
Background: Assessing the risk of measles outbreaks and identifying the susceptible parts of the population is essential to timely intervention. Infants between 6–12 months are increasingly susceptible to measles but evaluating the performance of high ...
Andreas Jensen, Michelle Malon, Jannet Svensson   +2 more
exaly   +6 more sources

Plaque Reduction Neutralization Test (PRNT) in the Congenital Zika Syndrome: Positivity and Associations with Laboratory, Clinical, and Imaging Characteristics [PDF]

Viruses, 2020
The short duration of viremia, low blood viral load, inaccessibility to timely specific diagnostic tests, and cross-reactions with other flaviviruses have hindered laboratory confirmation of Congenital Zika Syndrome (CZS).
Marizélia R. C. Ribeiro, Ricardo Khouri, Patrícia S. Sousa, Maria R. F. C. Branco, Rosângela F. L. Batista, Elaine P. F. Costa, Maria T. S. S. B. Alves, Gláucio A. Amaral, Marcella C. R. Borges, Eliana H. M. Takahasi, Líllian N. Gomes, Ana K. T. Mendes, Tamires B. Cavalcante, Luciana C. Costa, Alvina C. Félix, Nathalia C. S. Souza, Antônio A. M. Silva   +16 more
doaj   +3 more sources

Agreement between ELISA and plaque reduction neutralisation assay in Detection of respiratory syncytial virus specific antibodies in a birth Cohort from Kilifi, coastal Kenya. [version 1; peer review: 2 approved, 2 approved with reservations] [PDF]

Wellcome Open Research, 2019
Background: Severe disease associated with respiratory syncytial virus (RSV) infection occurs predominantly among infants under 6 months of age. Vaccines for prevention are in clinical development.
Joyce U. Nyiro, Patience K. Kiyuka, Martin N. Mutunga, Charles J. Sande, Patrick K. Munywoki, J. Anthony G. Scott, D. James Nokes   +6 more
doaj   +6 more sources

Variation in dengue virus plaque reduction neutralization testing: systematic review and pooled analysis [PDF]

BMC Infectious Diseases, 2012
Background The plaque reduction neutralization test (PRNT) remains the gold standard for the detection of serologic immune responses to dengue virus (DENV).
Rainwater-Lovett Kaitlin, Rodriguez-Barraquer Isabel, Cummings Derek AT, Lessler Justin   +3 more
doaj   +5 more sources

Triple Burden in the Democratic Republic of Congo: Climate Change, Armed Conflict, and the Silent Spread of Arboviruses. A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background The Democratic Republic of Congo (DRC) faces a “triple burden” of public health threats which includes climate change, protracted armed conflict, and the under‐recognized spread of arboviral diseases. Arboviruses, such as dengue, chikungunya, Zika, and yellow fever, are transmitted by Aedes aegypti and Aedes albopictus mosquitoes ...
Donnang S, Yokolo H, Makeda D, Ekouo J, Shams Z, Kaptso JAD, Kamgang JS, Waffo YV, Tague C.   +8 more
europepmc   +2 more sources

Avaliação da qualidade de calcários agrícolas através do PRNT [PDF]

Anais Da Escola Superior De Agricultura Luiz De Queiroz, 1988
Foram comparados os valores do PRNT de calcários agrícolas, empregando fórmulas que se baseiam em diferentes valores de eficiência relativa das frações granulométricas que compõem esses materiais. Foram utilizadas 22 amostras de calcários, sendo 12 de Rio Claro, Piracicaba e Tietê, Estado de São Paulo e as demais especialmente escolhidas visando ...
Bellingieri, P.A., Alcarde, J.C., Souza, E.C.A. de   +2 more
exaly   +4 more sources

Performance assessment and validation of a plaque reduction neutralization test (PRNT) in support to yellow fever diagnostic and vaccine clinical trials

Journal of Medical Virology, 2023
AbstractYellow fever (YF) virus is a mosquito‐borne virus belonging to the Flaviviridae family that circulates in tropical and subtropical areas of Africa and South America. Despite the availability of an effective vaccine, YF remains a threat to travelers, residents of endemic areas, and unvaccinated populations.
Moussa, Dia, Ndeye Sakha, Bob, Cheikh, Talla, Anne, Dupressoir, Camille, Escadafal, Mareme Seye, Thiam, Amadou, Diallo, Oumar, Ndiaye, Jean Michel, Heraud, Oumar, Faye, Amadou Alpha, Sall, Ousmane, Faye, Gamou, Fall   +12 more
exaly   +3 more sources