Results 21 to 30 of about 8,177 (201)

Nucleotide variants in prion-related protein (testis-specific) gene (PRNT) and effects on Chinese and Mongolian sheep phenotypes [PDF]

Prion, 2018
Studies of the ovine prion-related protein (testis-specific) gene (PRNT), including studies of genetic diversity, have highlighted its potential relationship to scrapie infection and economically important ovine traits. PRNT was previously reported to be
Shaoli Zhang, Xianyong Lan
exaly   +4 more sources

Standardization of Plaque Reduction Neutralization Test on 96-well Plates (micro-PRNT) for Zika Virus [PDF]

Anais do IV International Symposium on Immunobiological e VII Seminário Anual Científico e Tecnológico de Bio-Manguinhos, 2019
Introduction: Plaque Reduction Neutralization Test (PRNT) is considered the “gold standard” by the World Health Organization for the confirmatory diagnosis of Flavivirus infection from the determination of neutralizing antibodies.
M. Simões, Vanessa de Oliveira Santos, J. Linhares, Bruno Setatino, S. Silva, E. Miranda, S. M. Lima   +6 more
exaly   +3 more sources

Evaluation of accuracy and reliability of the plaque reduction neutralization test (micro-PRNT) in detection of yellow fever virus antibodies [PDF]

Biologicals, 2012
Yellow fever is a disease caused by the prototype virus of the genus Flavivirus and remains endemic in tropical forest regions from Africa and South America, despite the availability of effective vaccines. These are capable of inducing a rapid specific immune response, with the formation of neutralizing antibodies that appear early, are protective and ...
Marisol Simões
exaly   +4 more sources

Genetic associations with measles PRNT and IgG antibody response to MMR vaccination in 6- and 15-month-old children.

Vaccine
BACKGROUND Measles immunization is a cornerstone in public health, yet vaccine failure affects up to 10 % of the population, leaving some vaccinated individuals susceptible to infection.
Jesper Kiehn Sørensen, Andreas Jensen, A. C. Zimakoff, D. M. Vittrup, M. Malon, Sejun Kim, E. Hatley, J. Bybjerg-Grauholm, Simranjeet Kaur, F. Pociot, L. Stensballe, Jannet Svensson   +11 more
semanticscholar   +6 more sources

Dengue Plaque Reduction Neutralization Test (PRNT) in Primary and Secondary Dengue Virus Infections: How Alterations in Assay Conditions Impact Performance [PDF]

American Journal of Tropical Medicine and Hygiene, 2009
Dengue virus (DENV) infection is a worsening global health problem. The plaque reduction neutralization test (PRNT) is currently considered to be the “gold standard” to characterize and quantify circulating levels of anti-DENV neutralizing antibody (NAb).
, Richard G Jarman, Timothy P Endy
exaly   +4 more sources

Pseudovirus-Based Neutralization Assays as Customizable and Scalable Tools for Serological Surveillance and Immune Profiling [PDF]

Pathogens
Neutralizing antibodies (nAbs) are key indicators of protection against SARS-CoV-2, and their measurement remains essential for monitoring vaccine responses and population immunity.
Caio Bidueira Denani, Bruno Pimenta Setatino, Denise Pereira, Ingrid Siciliano Horbach, Adriana Souza Azevedo, Gabriela Coutinho, Clara Lucy Ferroco, Janaína Xavier, Robson Leite, Ewerton Santos, Maria de Lourdes Maia, Waleska Dias Schwarcz, Ivanildo Pedro Sousa   +12 more
doaj   +3 more sources

Comparison of measles IgG enzyme immunoassays (EIA) versus plaque reduction neutralization test (PRNT) for measuring measles serostatus: a systematic review of head-to-head analyses of measles IgG EIA and PRNT

BMC Infectious Diseases, 2023
Background As countries move towards or achieve measles elimination status, serosurveillance is an important public health tool. However, a major challenge of serosurveillance is finding a feasible, accurate, cost-effective, and high throughput assay to ...
Chelsea S Lutz, A. Z. Hasan, S. Bolotin, N. Crowcroft, F. Cutts, E. Joh, Stacie Loisate, W. Moss, S. Osman, K. Hayford   +9 more
semanticscholar   +4 more sources

Additional file 1 of Comparison of measles IgG enzyme immunoassays (EIA) versus plaque reduction neutralization test (PRNT) for measuring measles serostatus: a systematic review of head-to-head analyses of measles IgG EIA and PRNT

, 2023
Additional file 1: Supplemental Table 1. PRISMA statement for a systematic literature search checklist. Supplemental Table 2A. Studies evaluating EIA compared to PRNT. Supplemental Table 2B. Studies evaluating EIA compared to PRNT. Supplementary Table 3. Mediandiagnostic accuracy of EIA compared to PRNT by assay type and study quality.
Lutz, Chelsea S., Hasan, Alvira Z., Bolotin, Shelly, Crowcroft, Natasha S., Cutts, Felicity T., Joh, Eugene, Loisate, Stacie, Moss, William J., Osman, Selma, Hayford, Kyla   +9 more
openaire   +2 more sources

Upregulated lncRNA PRNT promotes progression and oxaliplatin resistance of colorectal cancer cells by regulating HIPK2 transcription

World Journal of Gastrointestinal Oncology
BACKGROUND Colorectal cancer (CRC) is the third most common cancer and a significant cause of cancer-related mortality globally. Resistance to chemotherapy, especially during CRC treatment, leads to reduced effectiveness of drugs and poor patient ...
Sainan Li, Shan Yang, Hao-Qi Wang, Tianli Hui, Meng Cheng, Xi Zhang, Bao-Kun Li, Gui-ying Wang   +7 more
semanticscholar   +3 more sources

Triple Burden in the Democratic Republic of Congo: Climate Change, Armed Conflict, and the Silent Spread of Arboviruses. A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background The Democratic Republic of Congo (DRC) faces a “triple burden” of public health threats which includes climate change, protracted armed conflict, and the under‐recognized spread of arboviral diseases. Arboviruses, such as dengue, chikungunya, Zika, and yellow fever, are transmitted by Aedes aegypti and Aedes albopictus mosquitoes ...
Donnang S, Yokolo H, Makeda D, Ekouo J, Shams Z, Kaptso JAD, Kamgang JS, Waffo YV, Tague C.   +8 more
europepmc   +2 more sources