Results 31 to 40 of about 5,813 (150)

Comparison of Serological Methods for Tick-Borne Encephalitis Virus-Specific Antibody Detection in Wild Boar and Sheep: Impact of the Screening Approach on the Estimated Seroprevalence

Viruses, 2023
Tick-borne encephalitis virus (TBEV) is a flavivirus transmitted by ticks. Serological screenings in animals are performed to estimate the prevalence and distribution of TBEV.
Gabrielle Trozzi, Nadjah Radia Adjadj, Muriel Vervaeke, Severine Matthijs, Charlotte Sohier, Nick De Regge   +5 more
doaj   +1 more source

A Modular Design of a Cholera Toxin B Subunit-Scaffolded Sub-Virion Nanoparticle Vaccine Against West Nile Virus. [PDF]

Microb Biotechnol
A recombinant West Nile virus (WNV) subunit vaccine was developed by displaying ED3 on a CTB scaffold. The fusion protein formed soluble nanoparticles in E. coli, eliciting strong, balanced, and specific neutralizing antibodies without cross‐reactivity, offering a safe, scalable subunit vaccine platform.
Byun H, Kim TH, Sung J, Lee JM, Shim SM, Kang SH, Kang H, Moon DH, Park SH, Kim D, Kim SJ, Kim S, Han G, Seong BL.   +13 more
europepmc   +2 more sources

Reporter Virus Neutralization Test Evaluation for Dengue and Zika Virus Diagnosis in Flavivirus Endemic Area

Pathogens, 2021
Reporter virus neutralization test (RVNT) has been used as an alternative to the more laborious and time-demanding conventional PRNT assay for both DENV and ZIKV. However, few studies have investigated how these techniques would perform in epidemic areas
Jannyce G. C. Nunes, Bruno T. D. Nunes, Chao Shan, Adriana F. Moraes, Tais R. Silva, Maria H. R. de Mendonça, Liliane L. das Chagas, Franco A. e Silva, Raimunda S. S. Azevedo, Eliana V. P. da Silva, Livia C. Martins, Jannifer O. Chiang, Livia M. N. Casseb, Daniele F. Henriques, Pedro F. C. Vasconcelos, Rommel M. R. Burbano, Pei-Yong Shi, Daniele B. A. Medeiros   +17 more
doaj   +1 more source

Performance Evaluation of the BZ COVID-19 Neutralizing Antibody Test for the Culture-Free and Rapid Detection of SARS-CoV-2 Neutralizing Antibodies

Diagnostics, 2021
Rapid and accurate measurement of SARS-CoV-2 neutralizing antibodies (nAbs) can aid in understanding the development of immunity against COVID-19. This study evaluated the diagnostic performance of a rapid SARS-CoV-2 nAb detection test called the BZ ...
Bo Kyeung Jung, Jung Yoon, Joon-Yong Bae, Jeonghun Kim, Man-Seong Park, Suk Yong Lee, Chae Seung Lim   +6 more
doaj   +1 more source

Nucleotide variants in prion-related protein (testis-specific) gene (PRNT) and effects on Chinese and Mongolian sheep phenotypes [PDF]

Prion, 2018
Studies of the ovine prion-related protein (testis-specific) gene (PRNT), including studies of genetic diversity, have highlighted its potential relationship to scrapie infection and economically important ovine traits. PRNT was previously reported to be highly polymorphic in Portuguese sheep. To characterize genetic polymorphisms in this gene in Asian
Jie, Li, Shaoli, Zhang, Sarantsetseg, Erdenee, Xiuzhu, Sun, Ruihua, Dang, Yongzhen, Huang, Chuzhao, Lei, Hong, Chen, Hongwei, Xu, Yong, Cai, Xianyong, Lan   +10 more
openaire   +2 more sources

Neutralizing Activity Against SARS-CoV-2 Delta and Omicron Variants Following a Third BNT162b2 Booster Dose According to Three Homologous or Heterologous COVID-19 Vaccination Schedules

Frontiers in Cellular and Infection Microbiology, 2022
With the emergence and rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron variants, escaping vaccine-induced immunity is a concern.
Ju-yeon Choi, Young Jae Lee, Jae-Hoon Ko, Su-Hwan Kim, Hye-Jin Kim, Hye Won Lee, Hyeonji Jeong, Tae-Yong Kim, Yeong Gyeong Jang, Hyo-jeong Hong, Min-Seong Kim, Sang Eun Lee, Yong Guan Kim, Eun Joo Chung, Heeji Lim, Sundong Jang, Kwangwook Kim, Sung Soon Kim, Jin Young Ahn, Jun Yong Choi, Yong Chan Kim, Yoon Soo Park, Kyong Ran Peck, Byoungguk Kim   +23 more
doaj   +1 more source

Differential Neutralization Profiles of 17DD Vaccinated Population to 17D-204 and 17DD Vaccine Strains

Vaccines
Background/Objectives: Yellow fever virus (YFV) (Flaviviridae, Orthoflavivirus) is the etiologic agent of yellow fever (YF), a vector-borne disease with significant morbidity and mortality across the tropics and neotropics, despite having a highly ...
Ana C. B. Terzian, Sasha R. Azar, Cassia F. Estofolete, Mauricio L. Nogueira, Nikos Vasilakis   +4 more
doaj   +1 more source

Comparative Analysis of Hemagglutination Inhibition and Plaque Reduction Neutralization Tests for Japanese Encephalitis Virus Antibody Detection

Viruses
Japanese encephalitis (JE) is a zoonotic disease caused by the Japanese encephalitis virus (JEV), belonging to the Flaviviridae family. Diagnosis of Japanese encephalitis (JE) based on clinical signs alone is challenging due to the high proportion of ...
Cui Li, Jianqing Wan, Deli Wang, Lu Xiao, Xuni Li, Cunshuai Zhang, Zhao Wang   +6 more
doaj   +1 more source

Variation in dengue virus plaque reduction neutralization testing: systematic review and pooled analysis

BMC Infectious Diseases, 2012
Background The plaque reduction neutralization test (PRNT) remains the gold standard for the detection of serologic immune responses to dengue virus (DENV).
Rainwater-Lovett Kaitlin, Rodriguez-Barraquer Isabel, Cummings Derek AT, Lessler Justin   +3 more
doaj   +1 more source

Using cluster analysis to reconstruct dengue exposure patterns from cross-sectional serological studies in Singapore

Parasites & Vectors, 2020
Background Dengue is a mosquito-borne viral disease caused by one of four serotypes (DENV1-4). Infection provides long-term homologous immunity against reinfection with the same serotype.
Sorawat Sangkaew, Li Kiang Tan, Lee Ching Ng, Neil M. Ferguson, Ilaria Dorigatti   +4 more
doaj   +1 more source