PLoS ONE, 2020 IntroductionMany arboviruses of public health significance are maintained in zoonotic cycles with complex transmission pathways. The presence of serum antibody against arboviruses in vertebrates provides evidence of their historical exposure but reveals ...
Narayan Gyawali +3 more
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Comparative Analysis of Hemagglutination Inhibition and Plaque Reduction Neutralization Tests for Japanese Encephalitis Virus Antibody Detection [PDF]
VirusesJapanese encephalitis (JE) is a zoonotic disease caused by the Japanese encephalitis virus (JEV), belonging to the Flaviviridae family. Diagnosis of Japanese encephalitis (JE) based on clinical signs alone is challenging due to the high proportion of ...
Cui Li +6 more
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Pseudovirus-Based Neutralization Assays as Customizable and Scalable Tools for Serological Surveillance and Immune Profiling [PDF]
PathogensNeutralizing antibodies (nAbs) are key indicators of protection against SARS-CoV-2, and their measurement remains essential for monitoring vaccine responses and population immunity.
Caio Bidueira Denani +12 more
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Dengue Plaque Reduction Neutralization Test (PRNT) in Primary and Secondary Dengue Virus Infections: How Alterations in Assay Conditions Impact Performance [PDF]
American Journal of Tropical Medicine and Hygiene, 2009 Dengue virus (DENV) infection is a worsening global health problem. The plaque reduction neutralization test (PRNT) is currently considered to be the “gold standard” to characterize and quantify circulating levels of anti-DENV neutralizing antibody (NAb).
Stephen J Thomas +2 more
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Value of anatomical partitioning of the retroperitoneal space in determining the origin of neurogenic tumors [PDF]
BMC CancerBackground To analyze the anatomical partitioning of the retroperitoneal space and determine the distribution patterns of primary retroperitoneal neurogenic tumors (PRNTs).
Yuwei Li +7 more
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Evaluation of accuracy and reliability of the plaque reduction neutralization test (micro-PRNT) in detection of yellow fever virus antibodies [PDF]
Biologicals, 2012 Yellow fever is a disease caused by the prototype virus of the genus Flavivirus and remains endemic in tropical forest regions from Africa and South America, despite the availability of effective vaccines. These are capable of inducing a rapid specific immune response, with the formation of neutralizing antibodies that appear early, are protective and ...
Marisol Simões
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An exploratory study to assess the influence of schistosomiasis on the occurrence of dengue virus in Madagascar [PDF]
Infectious Diseases of PovertyBackground Dengue virus (DENV) is the most prevalent mosquito-borne virus worldwide, with approximately half of the world’s population at risk of infection.
Jana Christina Hey +26 more
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Chimeric Vesicular Stomatitis Virus Bearing Western Equine Encephalitis Virus Envelope Proteins E2-E1 Is a Suitable Surrogate for Western Equine Encephalitis Virus in a Plaque Reduction Neutralization Test [PDF]
VirusesIn December 2023, infections of western equine encephalitis virus (WEEV) within Argentina were reported to the World Health Organization (WHO). By April 2024, more than 250 human infections, 12 of which were fatal, and 2500 equine infections were ...
Kerri L. Miazgowicz +7 more
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Montagem de controles internos para ensaios de PRNT: uma necessidade e um grande desafio [PDF]
Anais do VI Seminário Anual Científico e Tecnológico de Bio-Manguinhos, 2018 Felipe Figueiredo
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Standardization of Plaque Reduction Neutralization Test on 96-well Plates (micro-PRNT) for Zika Virus [PDF]
Anais do IV International Symposium on Immunobiological e VII Seminário Anual Científico e Tecnológico de Bio-Manguinhos, 2019 Marisol Simões +6 more
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