Results 141 to 150 of about 2,679,159 (249)

Characteristics of ascitic fluid and diagnosis of bacterial peritonitis in malignant ascites: An observational study

Journal of Hospital Medicine, EarlyView.
Abstract Background Bacterial peritonitis in patients with malignant ascites (BP‐MA) is an understudied, high‐mortality condition. While ascitic polymorphonuclear (PMN) cell count ≥ 250 cells/mm3 defines the diagnosis of spontaneous bacterial peritonitis (SBP) in patients with cirrhosis, an ascitic fluid parameter for the diagnosis of BP‐MA has not ...
Mark M. Kelly, Nicole Johnston, Joanne Kuznicki, Stacy A. Johnson, Hannah Imlay   +4 more
wiley   +1 more source

Increased Serum Soluble (Pro)renin Receptor Levels in Patients with Sarcopenia

International Journal of Endocrinology
Purpose. Sarcopenia is an advancing and widespread skeletal muscle condition characterized by the depletion of skeletal muscle mass. The (pro)renin receptor ((P)RR) is a multifaceted protein with both pathophysiological and physiological functions. (P)RR
Satoshi Morimoto, Haruki Sasaki, Chikahito Suda, Atsuhiro Ichihara, Nobuyuki Ura   +4 more
doaj   +1 more source

A comparative analysis of the prevalence of medicine classes and polypharmacy between community‐dwelling and residential aged care populations in Western Australia

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Polypharmacy is a global issue, particularly among residential aged care home (RACH) residents with multimorbidity and complex care needs. However, population‐level evidence on longitudinal trends and comparisons with community‐dwelling (CD) older adults remains limited.
David Lim, Ninh Ha, David Youens, Rachael Moorin, Andrew Stafford   +4 more
wiley   +1 more source

Determinants of Early Renal Function Recovery After TIPS in Patients With Portal Hypertension

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Renal dysfunction frequently occurs in patients with portal hypertension and is linked to unfavorable clinical outcomes. Transjugular intrahepatic portosystemic shunt (TIPS) has the potential to enhance renal perfusion through portal decompression; however, factors predicting early improvement in renal function remain insufficiently defined ...
Meng Jia, Yang Luo, Zhao‐Yang Tan, Xiao‐Ling Zhou, Xi‐You Zhang, Jing‐Ying Sun, Ye Du   +6 more
wiley   +1 more source

Comparative Effects of Angiotensin Receptor Blockers on Blood Pressure and Serum Urate in Patients With Hypertension and Hyperuricaemia: A Systematic Review and Network Meta‐Analysis

Medicine Bulletin, EarlyView.
Allisartan ranked best for serum urate reduction and showed favourable blood pressure control, whereas losartan also performed well overall. These rankings may inform ARB selection but should be interpreted cautiously because of inconsistency, heterogeneity and sparse direct evidence.
Xuanyao Li, Xinyi Wang, Xiaolei Ren, Yalin Wang, Hua Shao, Xueli Zhang   +5 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

AI‐Enabled Cardiac Rehabilitation for Patients With Heart Failure After Myocardial Infarction: Current Status and Future Prospects

Medicine Advances, EarlyView.
This article illustrates the current dilemmas of myocardial infarction patients after traditional cardiac rehabilitation, as well as the feasibility of using artificial intelligence to optimize and assist with rehabilitation programs such as by integrating mobile apps, wearables, ECGs, medication, vital signs, and assessment data; finally, the AI ...
Xinyuan Huang, Di Chen, Yumin Cai, Zihan Chen, Dongmei Xie, Chaoquan Peng, Yuanlong Li   +6 more
wiley   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

Precision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source