Results 131 to 140 of about 32,074 (246)

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, EarlyView.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

Renal tubular (pro)renin receptor deletion exacerbates kidney injury in <i>db/db</i> mice. [PDF]

Am J Physiol Renal Physiol
Stuart D, Peterson CS, Gopinath D, Sundar D, Wheatley W, Ramkumar N.   +5 more
europepmc   +1 more source

Potential of soluble (pro)renin receptor in kidney disease: can it go beyond a biomarker?

Am J Physiol Renal Physiol, 2022
Yang T.
europepmc   +1 more source

Effect of Medication Intake on Dental Implant‐Related Outcomes—A Scoping Review

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objective The objective of this scoping review was to evaluate the effect of systemic medications on dental implant outcomes in medically compromised patients. Material and Methods Electronic and manual searches were conducted for this scoping review.
Alberto Monje, Maria Costanza Soldini, Emilio Couso‐Queiruga, Álvaro Babiano, Vivianne Chappuis   +4 more
wiley   +1 more source

Inhibitory effect of (pro)renin receptor decoy inhibitor PRO20 on endoplasmic reticulum stress during cardiac remodeling. [PDF]

Front Pharmacol, 2022
Zhang J, Cheng YJ, Luo CJ, Yu J.
europepmc   +1 more source

PLIN5 Protects Against Ang II‐Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet–Mitochondria Contact

Cell Proliferation, EarlyView.
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang, Wenjie Chen, Jingjing Ke, Hongtu Hu, Zhuan Peng, Yue Qi, Guohua Ding, Jijia Hu   +7 more
wiley   +1 more source

Corrigendum: (Pro)renin receptor aggravates myocardial pyroptosis in diabetic cardiomyopathy through AMPK-NLRP3 pathway. [PDF]

Front Pharmacol
Li S, Zhang J, Zhao Y, Kang L, Jie H, Dong B.   +5 more
europepmc   +1 more source

Role of (pro)renin receptor in cyclosporin A-induced nephropathy.

Am J Physiol Renal Physiol, 2022
Hu J, Tan Y, Chen Y, Mo S, Hekking B, Su J, Pu M, Lu A, Du Y, Symons JD, Yang T.   +10 more
europepmc   +1 more source

(Pro)renin receptor promotes colorectal cancer progression through inhibiting the NEDD4L-mediated Wnt3 ubiquitination and modulating gut microbiota. [PDF]

Cell Commun Signal, 2023
Wang J, Ding Y, Li D, Zhu N, Nishiyama A, Yuan Y.   +5 more
europepmc   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source