Results 101 to 110 of about 13,492 (207)
Effect of probenecid on SR101-labeling.
A: Overlay of astroglial EGFP-fluorescence and SR101-fluorescence in the VLM after staining in CTRL conditions. B: Overlay of astroglial EGFP- and SR101-fluorescence after staining with Probenecid (Prob, 1 mM). C,D: Statistical comparison shows no change
Christian Schnell (117226) +2 more
core +1 more source
Current therapies for Parkinson’s disease (PD) only offer limited symptomatic alleviation but fail to hamper the progress of the disease. Thus, it is imperative to establish new approaches aiming at protecting or reversing neurodegeneration in PD. Recent
Xuan He +8 more
doaj +1 more source
The aims of the study was to determine antihyperuricemic activity of ethyl acetate and ethanol extractsof snake fruit (Salacca edulis Reinw.) var. Bongkok on Wistar male rats.
Leni Herliani Afrianti1)* +3 more
doaj
Background/Objectives: Probenecid (PBN) is a uricosuric agent that facilitates the excretion of uric acid and is used to treat gout. Here, a colon-targeted prodrug of PBN was designed to facilitate repositioning as a treatment for inflammatory bowel ...
Yeonhee Jeong +3 more
doaj +1 more source
Glaesserella parasuis (G. parasuis) causes Glässer’s disease and systemic inflammatory responses in the host. The currently available therapies have limited efficacy and fail to achieve a balance between anti-inflammatory and antibacterial effects.
Jingyang Li +13 more
doaj +1 more source
It is essential to understand the molecular mechanisms of influenza antiviral therapeutics to evaluate their efficacy. Virus plaque assays are commonly used to assess the antiviral effects of drugs on virus replication; however, this method is labor ...
Jackelyn Murray +5 more
doaj +1 more source
Probenecid-induced accumulation of 5-hydroxyindoleacetic acid and homovanillic acid in rat brain
The accumulation of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in rat brain has been examined after probenecid infusion over 8 h. At plasma probenecid concentrations of 200-400 μg mL−1 a steady state level in the accumulation of 5 ...
Maria Sunzel +2 more
core +1 more source
Effect of Probenecid on Cerebral and Cisternal Cerebrospinal Fluid Lactate Content
In this study, the eisternal CSF contents of lactate and glucose were sequentially measured in free-moving rats that had been administered probenecid, 200 mg/kg−1, drug diluent, or no injections.
V. MacMillan
core +1 more source
The aims of the study was to determine antihyperuricemic activity of ethyl acetate and ethanol extractsof snake fruit (Salacca edulis Reinw.) var. Bongkok on Wistar male rats. Wistar male rats administered with 100 and 200 mg/kg b.w ethyl acetat extract
Leni Herliani Afrianti +3 more
doaj

