Results 11 to 20 of about 915,695 (292)

High-throughput mapping of RNA solvent accessibility at the single-nucleotide resolution by RtcB ligation between a fixed 5′-OH-end linker and unique 3′-P-end fragments from hydroxyl radical cleavage

open access: yesRNA Biology, 2022
Given the challenges for the experimental determination of RNA tertiary structures, probing solvent accessibility has become increasingly important to gain functional insights.
Md Solayman   +3 more
doaj   +1 more source

Microarray probes and probe sets [PDF]

open access: yesFrontiers in Bioscience, 2010
DNA microarrays have gained wide use in biomedical research by simultaneously monitoring the expression levels of a large number of genes. The successful implementation of DNA microarray technologies requires the development of methods and techniques for the fabrication of microarrays, the selection of probes to represent genes, the quantification of ...
Hongfang, Liu, Ionut, Bebu, Xin, Li
openaire   +2 more sources

Probing leptogenesis [PDF]

open access: yesInternational Journal of Modern Physics A, 2018
The focus of this paper lies on the possible experimental tests of leptogenesis scenarios. We consider both leptogenesis generated from oscillations, as well as leptogenesis from out-of-equilibrium decays. As the Akhmedov–Rubakov–Smirnov (ARS) mechanism allows for heavy neutrinos in the GeV range, this opens up a plethora of possible experimental ...
Chun, Eung Jin   +14 more
openaire   +6 more sources

Blind Bi-canalicular Intubation Versus Endoscopic Guided Intubation in Treatment of Nasolacrimal Duct Obstruction in Children [PDF]

open access: yesInternational Journal of Medical Arts, 2023
Background: Congenital nasolacrimal duct obstruction is a common cause of epiphora in pediatrics. Probing is the primary treatment option. However, failure rate is high. Thus, many options are introduced without consensus on the optimal management option.
Ahmed Mohamed Sharaf   +2 more
doaj   +1 more source

DNA Methylation Cancer Biomarkers: Translation to the Clinic

open access: yesFrontiers in Genetics, 2019
Carcinogenesis is accompanied by widespread DNA methylation changes within the cell. These changes are characterized by a globally hypomethylated genome with focal hypermethylation of numerous 5’-cytosine-phosphate-guanine-3’ (CpG) islands, often ...
Warwick J. Locke   +11 more
doaj   +1 more source

Mobile Probing and Probes [PDF]

open access: yes, 2013
Mobile probing is a method, developed for learning about digital work situations, as an approach to discover new grounds. The method can be used when there is a need to know more about users and their work with certain tasks, but where users at the same time are distributed (in time and space).
Duvaa, Uffe   +3 more
openaire   +1 more source

Changing trends in the prevalence of visual impairment, uncorrected refractive errors and use of spectacles in Mahbubnagar district in South India

open access: yesIndian Journal of Ophthalmology, 2013
Background/Aim: The Andhra Pradesh Eye disease Study (APEDS) was a conventional cross-sectional study conducted in four locations during 1996-2000.
Srinivas Marmamula   +4 more
doaj   +1 more source

Explaining pretrained language models' understanding of linguistic structures using construction grammar

open access: yesFrontiers in Artificial Intelligence, 2023
Construction Grammar (CxG) is a paradigm from cognitive linguistics emphasizing the connection between syntax and semantics. Rather than rules that operate on lexical items, it posits constructions as the central building blocks of language, i.e ...
Leonie Weissweiler   +7 more
doaj   +1 more source

Characterization of 5-methylcytosine and 5-hydroxymethylcytosine in human placenta cell types across gestation

open access: yesEpigenetics, 2019
The placenta is an important organ in pregnancy, however, very little is understood about placental development at a molecular level. This includes the role of epigenetic mechanisms and how they change throughout gestation.
Rebecca L. Wilson   +7 more
doaj   +1 more source

A unique case of phaeohyphomycosis subretinal abscess in a patient with arthropathy and lung pathology

open access: yesIndian Journal of Ophthalmology, 2013
A 67-year-old former gold miner with rheumatoid arthritis, treated with steroids and methotrexate, presented to eye casualty with a painful right eye.
Bryan J Matthews   +4 more
doaj   +1 more source

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