Results 131 to 140 of about 335,473 (338)

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Microbiota profile and efficacy of probiotic supplementation on laxation in adults affected by Prader‐Willi Syndrome: A randomized, double‐blind, crossover trial

Molecular Genetics & Genomic Medicine, 2020
Background Probiotics may provide a benefit for adults with Prader‐Willi syndrome (PWS) experiencing constipation. The primary aim was to determine if Bifidobacterium animalis ssp. lactis B94 (B.
Zainab Alyousif, Jennifer L. Miller, Jeremie Auger, Mariana Sandoval, Amanda Piano, Thomas A. Tompkins, Wendy J. Dahl   +6 more
doaj   +1 more source

Intestinal histomorphology, autochthonous microbiota and growth performance of the oscar (Astronotus ocellatus Agassiz, 1831) following dietary administration of xylooligosaccharide [PDF]

, 2016
The present study investigates the changes in intestinal histomorphology, autochthonous microbiota and growth performance of the oscar, Astronotus ocellatus, following dietary administration of different levels of xylooligosaccharide (XOS).
Hoseinifar, S.H., Khalili, M., Sun, Y.-Z.   +2 more
core   +1 more source

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, EarlyView.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Modulation of tryptophan/serotonin pathway by probiotic supplementation in human immunodeficiency virus-positive patients: preliminary results of a new study approach [PDF]

, 2017
Background: To date, no data are available regarding the effects of probiotics on the pathway of tryptophan/serotonin metabolism among human immunodeficiency virus (HIV) 1–infected individuals.
Cavallari, Eugenio Nelson, Ceccarelli, Giancarlo, Corano Scheri, Giuseppe, D'Ettorre, Gabriella, DE GIROLAMO, Gabriella, Giustini, Noemi, Laghi, Luca, Mastrangelo, Andrea, Najafi Fard, Saeid, Pinacchio, Claudia, Schietroma, Ivan, Serafino, Sara, Statzu, Maura, Vullo, Annamaria, Vullo, Vincenzo   +14 more
core   +3 more sources

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

Advanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang, Mengyi Xu, Yan Zhang, Zhiwen Li, Danqing Song, Jing Pang, Ke Li, Yanxiang Wang   +7 more
wiley   +1 more source

Development and mechanism of an XOD-targeting fermented traditional Chinese medicine formula for gout prevention in goslings

Poultry Science
Xanthine oxidase (XOD) is a key target in managing gout. We developed a fermented traditional Chinese medicine (TCM) formula with strong XOD-inhibitory properties. Several TCMs and probiotics, including Cortex fraxini, Polygonum cuspidatum, Lactobacillus
Zhewei Zhang, Zhuangkun Tian, Chuanzhou Bian, Fayin Tang, Yanting Sun, Man Zhang, Yu Kang, YuChang Ning, Hui Ma, Xiaozhan Zhang, Hongxing Qiao   +10 more
doaj   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

Advanced Science, EarlyView.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao, Bingyao Bai, Xingqian Ye, Yiliang Lin   +3 more
wiley   +1 more source

Impact of Carbohydrates on the Aggregation of Probiotic Bacteria [PDF]

, 2014
Probiotic bacteria can be beneficial to the gastrointestinal tract in the human body in numerous ways. Autoaggregation may play a key role in allowing probiotics to prevent pathogenic organisms from colonizing the intestinal system. Currently, scientific
Davis, Kennedy
core  

Role of Probiotics in Human Gut Microbiome-associated Diseases.

Journal of Microbiology and Biotechnology, 2019
Probiotics are live microorganisms, including bacteria and yeast, which have been demonstrated to have beneficial effects on human health. Since probiotic bacteria have been constantly being studied, applications of probiotics have been considered as ...
Seon-Kyun Kim, R. Guevarra, You-Tae Kim, Joongi Kwon, Hyeri Kim, Jae Hyoung Cho, H. Kim, Ju-Hoon Lee   +7 more
semanticscholar   +1 more source