Results 61 to 70 of about 69,156 (235)

Impact of adherence to procalcitonin antibiotic prescribing guideline recommendations for low procalcitonin levels on antibiotic use [PDF]

, 2023
BACKGROUND: The Procalcitonin Antibiotic Consensus Trial (ProACT) found provision of a procalcitonin antibiotic prescribing guideline to hospital-based clinicians did not reduce antibiotic use.
Angus, Derek C., Chang, Chung-Chou H., Derek C. Angus, Huang, David T, Chung-Chou H. Chang, David T. Huang, Brian E. Malley, Angus, Derek C, Gimbel, Elizabeth, Malley, Brian E, Malley, Brian E., Michael J. Fine, Chang, Chung-Chou H, Fine, Michael J., for the ProACT Investigators, Yabes, Jonathan G., Fine, Michael J, Jonathan G. Yabes, Yabes, Jonathan G, Elizabeth Gimbel, Yealy, Donald M., Huang, David T., ProACT Investigators, Yealy, Donald M, Donald M. Yealy, Aaron M. Brown, Robert L. Sherwin, R. Gentry Wilkerson, Matthew J. Exline, Alpesh N. Amin, Octavia M. Peck Palmer, Shahram Lotfipour, Yohei Doi, Lisa A. Weissfeld, null null, Feras H. Khan, Michael W. Donnino, Lauren T. Southerland, Kourtney A. Wofford, Franziska F. Jovin, Colleen M. Rafferty, Frank LoVecchio, Elizabeth A. Gimbel, Tianyuan Xu, William D. Dachman, Tammy L. Eaton, Jean M. Hammel, David L. McCullum, Henry E. Wang, Raghu R. Seethala, Michael K. Mansour, Jonathan M. Fine, Imoigele P. Aisiku, Brian Suffoletto, Francis Pike, Peter C. Hou, Michael R. Filbin, Heather A. Prunty, Michael C. Kurz, John M. Holst, Michelle A. Fischer, Ashley M. Ryman, Thomas E. Terndrup   +62 more
core   +1 more source

Bacterial infections in patients with COVID-19: the impact of procalcitonin testing on antibiotics prescription in the real world

BMC Infectious Diseases
Background Bacterial infections are not prevalent among patients hospitalized with COVID-19, while unnecessary prescription of antibiotics was commonly observed.
Grace CY Lui, Catherine SK Cheung, Terry CF Yip, Mandy SM Lai, Timothy CM Li, Grace LH Wong   +5 more
doaj   +1 more source

Procalcitonin-Guided Management and Duration of Antibiotic Therapy in Critically Ill Cancer Patients With Sepsis (Pro-Can Study): A Randomized Controlled Trial

Critical Care Explorations
OBJECTIVES:. To evaluate the effect of procalcitonin-guided management on the duration of antibiotic therapy in critically ill cancer patients with sepsis. DESIGN:. Randomized, controlled, single-blinded trial. SETTING:. A comprehensive multidisciplinary
Lama H. Nazer, PharmD, BCPS, FCCM, Wedad Awad, PharmD, BCPS, Hadeel Thawabieh, PharmD, BCPS, Aseel Abusara, PharmD, BCPS, BCIDP, Deema Abdelrahman, PharmD, BCIDP, Awad Addassi, MD, Osama Abuatta, MD, Maher Sughayer, MD, Yahya Shehabi, PhD, FCICM   +8 more
doaj   +1 more source

Toxoplasma gondii Infection After Kidney Transplantation: A Case Report and Literature Review

Organ Medicine, EarlyView.
Toxoplasma gondii infection after kidney transplantation is rare and presents with nonspecific clinical manifestations; however, the associated mortality rate is high. We discuss the relevant literature, clinical manifestations, therapeutic regimens, and prognoses of post‐transplantation toxoplasmosis.
Peng Zhang, Xingqiang Lai, Rongxin Chen, Li Li, Jiali Fang, Guanghui Li, Junjie Ma, Luhao Liu, Zheng Chen   +8 more
wiley   +1 more source

Serum Procalcitonin Level and Mortality Risk in Critically ill Patients with Ventilator-Associated Pneumonia

Cellular Physiology and Biochemistry, 2015
Background/Aims: The prognostic role of serum procalcitonin level in critically ill patients with ventilator-associated pneumonia was unclear. The aim of our study was to investigate the relationship between serum procalcitonin level and mortality risk ...
Bo Li, Xin Zhao, Shumei Li
doaj   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

VIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi, Ngoan Thi Thao Nguyen, Riccardo Zulli, Jacopo Giaretta, Fariba Dehghani, Syamak Farajikhah   +5 more
wiley   +1 more source

Maternal Plasma Procalcitonin Concentrations in Pregnancy Complicated by Preterm Premature Rupture of Membranes

Mediators of Inflammation, 2007
Objectives. Our objective is to compare maternal plasma procalcitonin concentrations in preterm premature rupture of membranes (pPROM) and premature rupture of membranes (PROM) at term with their levels in uncomplicated
Andrzej Torbé
doaj   +1 more source

Correlation Between Neutrophil-lymphocyte Count Ratio and Procalcitonin in Sepsis and Septic Shock

Majalah Kedokteran Bandung, 2019
Sepsis is one of the leading causes of death in patients with infection. Procalcitonin is one of the laboratory parameters that is used to differentiate between thesystemic inflammatory responses caused by pathogens and non-pathogens.
Jonathan Jonathan, Erwin Pradian, Ardi Zulfariansyah   +2 more
doaj   +1 more source

Delivery and adherence of biomarker‐guided antibiotic treatment protocols in the ADAPT‐Sepsis clinical trial: an in‐trial descriptive process evaluation of daily procalcitonin‐ and C‐reactive protein‐guided protocols

Anaesthesia, EarlyView.
Summary Introduction Biomarker‐guided antibiotic protocols using daily procalcitonin or C‐reactive protein have been proposed to optimise antibiotic duration in sepsis. This pre‐planned process evaluation of the ADAPT‐Sepsis trial examined delivery and clinician adherence to procalcitonin‐ and C‐reactive protein‐guided protocols.
Ranjit Lall, Anower Hossain, Ruth Poole, Christina Lloydwin, Harley Anderson, Judith White, Paul Dark, on behalf of the ADAPT‐Sepsis collaborators, Julian Bion, Alasdair MacGowan, Paul McCrone, Maurice O'Kane, Ben Attwood, Gordon Sturmey, Janet Prentice, Ly‐mee Yu, Tom Clutton‐Brock, Duncan Young, John Simpson, Kay Marshall, Simon Gates, Judith White, Dipesh Mistry, Scott Regan, Nicola McGowan, Dalbir Kaur, Chen Ji, Nessa Nevels, Ingeborg D Welters, Karen Williams, David Shaw, Victoria Waugh, Julie Patrick‐Heselton, Carol Paisley, Suzannah Phillips, Emily Johnson, Jaime Fernandez Roman, Maria Lopez Martinez, Arra Mahiya, Daniel Watkin, Zachary Thomas, Andrew Davison, Sofia Farina, Maria Norris, Silvia Manes, Jin‐Xi Yuan, Josh Colfar, Caitlin Lythgoe, Ibrahim Almafreji, Lisa Bailey, Robert Parker, Ian Turner‐Bone, Laura Wilding, Michaela Lloyd, Harriet Murrant, Leanne Smith, Ben Morton, Dylan Middleton, William McCaig, Amie Hughes, Lucy Fuller, Dominic Kay, Sharon Barber, Jane Parez, Stephanie Lee, Reece Doonan, Lisa Swindells, Jessica Pendlebury, Jessica Holden, Jacob Hadfeild, Jay Naisbitt, Andrew Caxton, Emma Parkin, Daniel Horner, Anila Sukumaran, Benedict Gyamerah, Alice Dunombe, DR Chris Taylor, DR Wadhi Habeichi, Joanna Borzomato, Paul Ferris, Justin Roberts, James Nesbitt, Jonathan Clayton, John Macdonald, Alistair Roy, Anthony Rostron, Lindsey Woods, Sarah Cornell, Kimberley Rogerson, Jo Boxall, Trina Burns, Susan Cooper, Kirstie Knight, Sarah Constable, Laura Kenny, Jonathan Vernazza, Maxwell Richardson, Matthew Bickerton, Andrew Camplejohn, Roseanne Cope, Julie Sheriff, Helena Baker, Jessica Watson, Jodie Sedgwick, Simon Whiteley, Max Ridley, Richard Gould, Sarah Perrin, Elizabeth Wilby, Susan Trott, Sheila Salada, Sarah Watts, Zoe Friar, Bethan Ogg, Clare Howcroft, Kate Long, Alistair Morris, Julia Sampson, Alexandra Gibbins, Celia Peters, Megan Meredith, Alice Baddeley, Anthony Baidoo, Dan Harvey, Alexandra McCoy, Sophie Lubbock, David Ford, Amy Clark, Laura Lloyd, Mohammed Habib, Gemma Clark, Ian King, Carla Goode, Angela Sellick, Shova Sharma, Anita Assi, Jennifer Dengate, Matthew Grice, Laura Brammer, Chinyere Ajonu, Samuel Redgate, Wendy Smith, Manjinder Khakh, Hannah Howson‐Wells, Simon Atkin, Max Casbon, Frances Olsen, Bhavin Mistry, Victoria Mitchinson, Aysha Talbot, Iain McCullagh, Arti Gulati, Benjamin Brown, Stephanie Grieveson, Tara Shrestha, Ian Storey, Fatima Simoes, Verity Calder, Carole Hays, Maite Babio‐Galan, Deborah White, Jennifer Collins, Leigh Dunn, Susan Taylor, Luzgie Gavina, Tessa Wilkinson, Pamela Garcia, Lauren Butler, James Savage, Jayne Harwood, Sarah Cook, Stephen Hamilton, Jonathan Shelton, Ian Clement, Samantha Burn, Nathan Carroll, Lauren Clark, Lauren Ferguson, Sam Foggett, Alison Hague, Tracy Handley, Chelsea Hewison, Samantha Kitchener, Laura McEachan, Nicole McEwen, Ryan Perry, Olivia Purdy, Amie Thomson, Stephanie Williams, Glykeria Pakou, Helder Filipe, Margaret McNeil, Sara Mingo, Catarina Veiga, Poh Choo Teoh, Amitaa Maharajh, Mark De Neef, Coral Cole, Alex Ross, Mark Belsham, Shatha Abu‐Hijleh, Saida Solkar, Oghenemega Okotete, Peter D G Alexander, Luke Ward, Joanne Rothwell, Sherly George, Hannah Currie, Katharine Sellers, Karen Morris, Jan Hansel, Gavin Perkins, Jo Gresty, Ellie Reeves, Teresa Melody, Helen Taylor, Sara Bawa, Celinamma Maliaykal, William McIver, Mohamed Mooradun, Tay‐yibah Mohamed, Heather Willis, Aidan Butler, Amy Hooper, Adam Boulton, Lucie Linhartova, Rachel Smith, Daniel Park, Anna Dennis, Joyce Yeung, Hozefa Ebrahim, Neil Crooks, Sarah Milton‐White, Sarah Ballinger, Natalie Carling, Julia Sampson, Chloe Norman, Marie Thomas, Alexandra Nance, Emma Evans, Lesley Horton, Madhu Balasubramaniam, Rebecca Flanagan, Emma McKenna, Scott Latham, Danielle Hollick, Chinari P K Subudhi, Celia Chu, Katy Edwards, Rashmi Gupta, Carolyn Williams, Lindwe Mashangombe, Misbah Javed, Timothy Walsh, Maria Amamio, Gillian Andrew, Lucy Barclay, Sophie Birch, Kate Briton, Lisa‐Marie Butt, Sarah Clark, Jessica Crossan, Katherine Doverman, Michael Gillies, David Griffith, David Hope, Kallirroi Kefala, Ian Laurenson, Nazir Lone, Lucy Macdonald, Craig Marshall, Corrienne McCulloch, Gregor McNeill, Nicola Rea, Scott Simpson, Jo Singleton, Elzbieta Czarniak, Olga Lucia Moncayo Nieto, Joanne Thompson, Ceri Lynch, Bethan Gibson, Piroska Toth‐tarsoly, Zolton Auer, Daniel Law, Jayparaska Singh, Shaun Oram, Arsalan Zaki, Alan Dodd, Bethan Deacon, Lisa Roche, Leanne Jones, Justyna Smeaton, Kevin Agravante, Oladele Akinyoola, Keri Turner, Joanne Pugh, Sam Evans, Lisa Mellish, Angharad Rees, Geraint Lewis, John Burke, Nia Bromage, Nicola Llewellyn, Justine Evans, Marlo Constantino, Redmond P Tully, Andrew Drummond, Joy Dearden, Michelle Mulcahy, Carrole Blessen, Angiy Vian‐Michael, Grainne O'Connor, Jonathan Scargill, Sarah Winnard, James McNamee, Danny McAuley, Peter McGuigan, Kathyrn Ward, Justine Ward, Aisling O'Neill, Stephanie Finn, Erin Collins, Jackie Green, Christine Turley, Gerard Quinn, Matthew Adams, Chris Wright, Gareth McKeeman, Rory Loughlin, Lynsey Reilly, Heather Gallagher, Steve Coward, Rachel Morrison, Shondipon Laha, Sushruth Madanapalli Raghunath, Alex Jude Fonseca, Alexandra Williams, Sacha Connor, Rebecca Allock, Lisa Halsall, Sean McMullen, Jayanthi Rajasekar, Sarah Purvis, Isha Garg, Vijay Jagannathan, Hillie Corr, Magda Stefaniak, Simon Sinclair, Chris Wilson, David Brealey, Niall MacCallum, Ingrid Hass, Georgia Bercades, Deborah Smyth, Gladys Martir, Anna Reyes, Maria Alexandra Zapata Martinez, Laura Gallagher, Hodan Omer, Jonathan Bannard‐Smith, Deborah Paripoorani, Charlotte Taylor, Gregory Yates, Katharine Wylie, Sadiya Salah, Fionn Quilty, Stephen Bonner, Jeremy Henning, Amy Thompson, Jessica Jones, Steven Liggett, Craig Mower, Sarah Bircham, Bobette Kamangu, Abiola Shoremekun, Anitha Ratnakumar, Keith Hugill, Tom Lawton, Amy Robinson, Rafaq Azad, Megan Kitching, Chris Cockcroft, Louise Akeroyd, Jackie Todd, Susan Kimachia, Lisa Burgess, Shereen Bano, Fiona Jutsum, Laura Price, Susie Pajak, Hannah Gibson, Mark Bates, Karen Reid, Alison Bland, Alison Stephens, Denise Donaldson, Mandy Beekes, Jo Stickley, Colene Adams, Amy Bowes, Sanal Jose, Rebecca Wilcox, Rachel Rikunenko, Maria Houghton, Andrew Donnelly, Julie Summers, Christopher Mowatt, Katherine Richmond, Rebecca Jones, Tammy Davie, Michael Barnsley, Mick Pursglove, James Pearce, Philippa Lane, Natasha Cole, Megan Phillips, Joanna Jasiewicz, Sarah Hamad, Jyoti Sharma, Muhammad Adeeb, Mohammad Qasim, Lisa Barnsley, Louise Walton, Claire Wright, Helen Kaura, Cathy McCormack, Dave Latham, Emily Wynne, Catherine McCormack, Kathy Richmond, Christopher Thompson, Minnie Gellamucho, Jane Delaney, Michelle Davies, Elisa Sernicola, Lucy Bailey, Angelene Cope, Claire Hudson, Umar Mohyddin, Jack Lee, Ben Storey‐Waters, Faye Halliday, George Mathew, Sarah Birch, Dumindu Karangoda, Estefania Treus, Leanne Howard, Georgina Luck, Claire Gabriel, Richard Lowsby, Elijah Matovu, Katherine Pagett, Deborah Maren, Tenifayo Adeyemo, Hannah David, Mark Quiambao, Joanne Harold, Sheron Clarke, Valery Gurov, Anthony Mkandhla, Chris Duff, Helen Duce, Tony Whitehouse, Amy Clark, Liz Ratcliffe, Anna Casey, Natalie Dooley, Karen Ellis, Christopher Sheridan, Lisa Moody, Puja Mulholland, Rachel Webster, Samantha Harkett, Sophia Beddows, Caroline Dooley, Eamonn Reda, Stephanie Goundry, Elaine Spruce, Tonny Veenith, Dhruv Parekh, Natalie Walmsley, Malikah Saba, Rebecca Gill, Esther Thomas, Jaimin Patel, Mansoor Bangash, Craig Denmade, Sarah White, Rosie Clare, Ya‐Wen J Huang, Dawn Herbert, Lynn Rowbottom, Madeleine McGrady, Matt Thomas, Paul Thomas, Ruth Worner, Borislava Borislavova, Kati Hayes, Beverley Faulkner, Emma Gendall, Elizabeth Goff, Hayley Blackmore, Mike Spivey, Sarah Bean, Karen Burt, Anthea Pattterson, Lisa Vipond, Matthew Martin, Nick Vallotton, Samuel Waterman, Michael Kelsey, Ana Zuriaga‐Alvaro, Loreta Mostoles, Anezka Pratley, Nabeel Amiruddin, Helen Ashby, Gemma Wood, George Priestley, Phil Antil, Joseph Carter, David Yates, Rob Ferguson, Harriet Carter, Zoe Cinquina, Dewi Williams, Catherine Jardine, Karen Craik, Julia Anderson, Aditya Adhikarla, Christopher Bassford, Laura Wild, Jayachandran Radhakrishnan, Stacey Cotterall, Mandy Austin, Mark Wilkinson, Niall Harbison   +536 more
wiley   +1 more source

Association of Elevated C‐Reactive Protein in Term Newborns With Neonatal Factors and Gut Microbiota

Acta Paediatrica, EarlyView.
ABSTRACT Aim Plasma C‐reactive protein (CRP) is widely used to assess neonatal infection, although mild, unexplained elevations are common in healthy newborns. We examined relationships between non‐infectious CRP levels and neonatal factors, and early gut microbiota composition in term infants.
Susanna Gardemeister, Aki Saarikivi, Samuli Rautava, Jani Mälkönen, Willem M. de Vos, Katri Korpela, Kaija‐Leena Kolho   +6 more
wiley   +1 more source