Results 51 to 60 of about 69,156 (235)

Procalcitonin multicentric CAP identification

, 2022
this dataset was conceived to analyse the discriminatory efficacy of procalcitonin in differentiating antibiotic-requiring CAP from purely viral ...
Stefano Malinverni (8961053), Fatima-Zohra Bouazza (10527617), Silvia Lazzaroni (2716531)   +2 more
core   +1 more source

The use and misuse of procalcitonin in the management of pneumonia: a retrospective analysis at a large tertiary care center

Antimicrobial Stewardship & Healthcare Epidemiology
Objective: Antibiotics overuse leads to bacterial resistance. The biomarker procalcitonin rises with bacterial pneumonias and remains normal in viral respiratory tract infections.
Doris C. Obimba, Aaron Shaykevich, Danielle R. Vitale, Christopher A. Rudmann, Heather Korrie, Joseph Miles, Christopher Noel, Ivayla I. Geneva   +7 more
doaj   +1 more source

Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors

FlexMat, EarlyView.
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu, Yubing Hu, Dong Wang, Ben Zhong Tang   +3 more
wiley   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Procalcitonin as a Predictive Tool for Death and ICU Admission among Febrile Neutropenic Patients Visiting the Emergency Department

Medicina, 2022
Background and Objectives: Risk stratification tools for febrile neutropenia exist but are infrequently utilized by emergency physicians. Procalcitonin may provide emergency physicians with a more objective tool to identify patients at risk of ...
Christopher J. Coyne, Edward M. Castillo, Rebecca A. Shatsky, Theodore C. Chan   +3 more
doaj   +1 more source

METTL7B Expression in Sepsis: Association With Disease Severity and 28‐Day Mortality

Journal of Clinical Laboratory Analysis, EarlyView.
This prospective cohort study demonstrates that whole blood METTL7B expression is significantly elevated in sepsis patients upon ICU admission and independently associates with disease severity and 28‐day mortality. METTL7B alone predicted 28‐day mortality with an AUC of 0.779, and its combination with dynamic SOFA score and PCT achieved the highest ...
Yuxuan Zhang, Yonghua Wang, Mengjiao Yang, Dan Huang   +3 more
wiley   +1 more source

Diagnostic Value of Cerebrospinal Fluid Procalcitonin in Differentiating Bacterial and Aseptic Meningitis: A Cross-Sectional Study [PDF]

Zagazig University Medical Journal
Background: In adults, procalcitonin (PCT) has been the focus of various investigations about its diagnostic accuracy in differentiating between bacterial and aseptic meningitis in adults.
Abdallah Nawara, Mohammed El Saeed, Doaa AbdElmon, Walid Hamad, Heba Abd El Khalik   +4 more
doaj   +1 more source

The Association Between Salivary Procalcitonin and Periodontitis in Type 2 Diabetic Patients

Basrah Journal of Surgery, 2022
One of the most prevalent conditions that affects teeth, periodontitis causes the surrounding and supporting tooth structure to be destroyed. Procalcitonin may be a helpful marker to determine the severity of infection, forecast the prognosis, and track ...
Zahraa Moayed Hameed, Alaa Omran
doaj   +1 more source

Biochemical testing and pathology reveal rare cause of pediatric acute liver failure: Hyperornithinemia‐hyperammonemia‐homocitrullinuria syndrome

JPGN Reports, EarlyView.
Abstract Hyperornithinemia‐hyperammonemia‐homocitrullinuria (HHH) syndrome is a rare metabolic condition that can cause lethargy, ataxia, tachypnea, nausea, vomiting, seizures, coma, and acute liver failure. We present a 26‐month‐old female with acute liver failure who was diagnosed with HHH 1 week after admission. Histology revealed an acute hepatitic
Tierra L. Mosher, Kathryn S. Czepiel, Matthew B. Neu, Andrea Carolina Cortes Fernandez, L. Walden Browne, Annie D. Niehaus, Roberto Gugig   +6 more
wiley   +1 more source

Procalcitonin as an acute phase marker [PDF]

Annals of Clinical Biochemistry, 2001
Procalcitonin is a 14-kDa protein encoded by the Calc-I gene along with calcitonin and katacalcin. The function and regulation of this protein are quite different from those of the other gene products. Blood concentrations of procalcitonin are increased in systemic inflammation, especially when this is caused by bacterial infection.
J, Whicher, J, Bienvenu, G, Monneret
openaire   +3 more sources