Results 41 to 50 of about 61,936 (249)

PROFILE OF PROCALCITONIN LEVELS IN SEVERE–CRITICAL COVID-19 PATIENTS [PDF]

, 2021
The diagnostic and therapeutic modalities of COVID-19 are still being researched and developed. One of the diagnostic modalities in the treatment of COVID-19, especially in patients with severe and critical symptoms, is procalcitonin.
Room, Asyikun Nasyid, Muchtar, Faisal, Amin, Hisbullah   +2 more
core   +1 more source

The utility of procalcitonin for identifying secondary infections in patients with influenza or COVID-19 receiving extracorporeal membrane oxygenation

Therapeutic Advances in Infectious Disease
Background: Identifying secondary infections in patients receiving extracorporeal membrane oxygenation (ECMO) presents challenges due to the ECMO circuit’s influence on traditional signs of infection.
Kajal D. Patel, James K. Aden, Michal J. Sobieszczyk, Joseph E. Marcus   +3 more
doaj   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

The Assessment of Vitamin D, Antimicrobial Peptides and Procalcitonin in Bronchiectasis [PDF]

, 2014
My research investigated the distribution of antimicrobial peptides (cathelicidin and β-defensin 2), vitamin D and the inflammatory marker procalcitonin, between systemic and localised respiratory levels in stable bronchiectasis patients.
Gartner, Sarah Nicole
core  

Limited diagnostic value of procalcitonin in early diagnosis of adult onset Still’s disease [PDF]

, 2016
A 17-year-old female patient was referred to the Infectious Diseases Ward because of fever lasting for 14 days. On admission to the hospital the patient was in a generally good state, without any abnormalities on physical examination.
Ewelina Gowin, Jacek Wysocki
core   +1 more source

Serum procalcitonin as an early inflammatory marker in pediatric ventilator-associated pneumonia: A prospective observational study

Journal of Pediatric Critical Care, 2021
Background: Delayed diagnosis of ventilator-associated pneumonia (VAP) in pediatric patients is associated with accentuated risk of morbidities and mortality. Early diagnosis of VAP is challenging.
Devki Nandan, Manju Nimesh, Sushil Kumar, Lucky Manik, J Sudarshan, Nandini Duggal   +5 more
doaj   +1 more source

Age‐associated immune dysregulation links to disease severity in macrolide‐resistant Mycoplasma pneumoniae pneumonia: Insights from a comparative juvenile–adult mouse model

Animal Models and Experimental Medicine, EarlyView.
Macrolide‐resistant Mycoplasma pneumoniae (MRMP) infected both juvenile and adult mice, with results compared to normal juvenile mice. The findings revealed comparable bacterial loads between juvenile and adult mice, yet juvenile mice exhibited more severe lung damage and elevated levels of inflammatory cytokines.
Xuejun Li, Yudong Wang, Liyong Liu, Mengmeng Gong, Jinlong Wang, Yuqing Cao, Zhixin Sun, Fanliang Meng, Qiuyan Wang, Hongji Wu, Fei Zhao, Yan Ma, Yibai Xiong   +12 more
wiley   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Plasma procalcitonin in rheumatic diseases [PDF]

, 2003
Data on the origin and biological function of procalcitonin, the pro-hormone of calcitonin, are scarce. Since this peptide can be induced in bacterial invasive infections, serum procalcitonin levels may be useful in differential diagnosis of systemic ...
R. Caporali, Montecucco, C, C. Perotti, C. Montecucco, Scirè, C, Caporali, R, Perotti, C, C.A. Scirè   +7 more
core   +1 more source

Procalcitonin Level Differences in Patients with Liver Cirrhosis Without Bacterial Infection

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2017
Background: Procalcitonin level can increase in patients with liver cirrhosis without bacterial infection. The aim of this study is to identify the role of procalcitonin in patients with liver cirrhosis without bacterial infection.
Oska Mesanti, Rino Alvani Gani, Marcellus Simadibrata, Suhendro   +3 more
doaj   +1 more source