The use of procalcitonin in the determination of severity of sepsis, patient outcomes and infection characteristics. [PDF]
OBJECTIVE:The primary objective of this study was to determine the correlation between procalcitonin values and illness severity by evaluating the degree of end organ dysfunction using the Sequential Organ Failure Assessment score, length of stay and the
Iram Yunus, Anum Fasih, Yanzhi Wang
doaj +1 more source
Multi-marker approach using procalcitonin, presepsin, galectin-3, and soluble suppression of tumorigenicity 2 for the prediction of mortality in sepsis [PDF]
Background: Biomarker could be objective and reliable tools to predict mortality in sepsis. We explored the prognostic utilities of emerging biomarkers in septic patients and questioned whether adding biomarkers to the clinical variables would improve ...
Hanah Kim +5 more
core +2 more sources
Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care [PDF]
Although many sepsis biomarkers have shown promise in selected patient groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice.
Berger, Mario +10 more
core +2 more sources
Implementation and impact of pediatric antimicrobial stewardship programs: a systematic scoping review. [PDF]
Background: Antibiotics are the most common medicines prescribed to children in hospitals and the community, with a high proportion of potentially inappropriate use. Antibiotic misuse increases the risk of toxicity, raises healthcare costs, and selection
Barbieri, E +6 more
core +2 more sources
Purpose of review: This review discusses the current developments in biomarkers for sepsis. Recent findings: With quantum leaps in technology, an array of biomarkers will become available within the next decade as point-of-care tools that will likely ...
Singer, M
core +1 more source
Procalcitonin in Takayasu Arteritis [PDF]
To the Editor: Procalcitonin (PCT) is an acute-phase protein, a precursor of the hormone calcitonin1. Microbial constituents and proinflammatory mediators such as tumor necrosis factor-α (TNF), interleukin 6 (IL-6), and interferon-γ induce ubiquitous PCT expression during bacterial, parasitic, or fungal infections1,2.
Tombetti, Enrico +8 more
openaire +4 more sources
Serum procalcitonin and C-reactive protein in the evaluation of bacterial infection in generalized pustular psoriasis [PDF]
Background There is an obvious need for more prompt and specific biomarkers of bacterial infections in generalized pustular psoriasis patients. Objective The aim of this study was to evaluate the diagnostic properties and define appropriate cut-off ...
Siyu Wang, Zhen Xie, Zhu Shen
doaj +2 more sources
Procalcitonin is a biomarker of systemic inflammation and may have importance in the immune response. The metabolic response to elevated procalcitonin in critical illness is not known.
Hirotada Kobayashi +3 more
doaj +1 more source
Early-onset neonatal sepsis: Still room for improvement in procalcitonin diagnostic accuracy studies [PDF]
To perform a systematic review assessing accuracy and completeness of diagnostic studies of procalcitonin (PCT) for early-onset neonatal sepsis (EONS) using the Standards for Reporting of Diagnostic Accuracy (STARD) initiative.EONS, diagnosed during the ...
Bonci, Enea +5 more
core +2 more sources
Diagnostic Accuracy of Procalcitonin upon Emergency Department Admission during SARS-CoV-2 Pandemic
Introduction: Procalcitonin is a marker for bacterial diseases and has been used to guide antibiotic prescription. Procalcitonin accuracy, measured at admission, in patients with community-acquired pneumonia (CAP), is unknown in the current severe acute ...
Stefano Malinverni +10 more
doaj +1 more source

