Results 31 to 40 of about 61,579 (261)

Procalcitonin in Pediatrics

, 2013
Over the past two decades, the body of literature on the clinical usefulness of procalcitonin (PCT) in adults has grown rapidly. Although this approach has led to increased insight, it has also prompted debate regarding its potential use in diagnosis and management of severe infection.
1, 2)Lucia Pacifico, 3)John F. Osborn, 1)Fabio Natale, 1)Flavia Ferraro, 1)Mario De Curtis, 3) Claudio Chiesa   +6 more
openaire   +5 more sources

Impact of adherence to procalcitonin antibiotic prescribing guideline recommendations for low procalcitonin levels on antibiotic use [PDF]

, 2023
BACKGROUND: The Procalcitonin Antibiotic Consensus Trial (ProACT) found provision of a procalcitonin antibiotic prescribing guideline to hospital-based clinicians did not reduce antibiotic use.
Angus, Derek C., Chang, Chung-Chou H., Derek C. Angus, Huang, David T, Chung-Chou H. Chang, David T. Huang, Brian E. Malley, Angus, Derek C, Gimbel, Elizabeth, Malley, Brian E, Malley, Brian E., Michael J. Fine, Chang, Chung-Chou H, Fine, Michael J., for the ProACT Investigators, Yabes, Jonathan G., Fine, Michael J, Jonathan G. Yabes, Yabes, Jonathan G, Elizabeth Gimbel, Yealy, Donald M., Huang, David T., ProACT Investigators, Yealy, Donald M, Donald M. Yealy   +24 more
core   +1 more source

Hospital physicians’ experiences with procalcitonin – implications for antimicrobial stewardship; a qualitative study

BMC Infectious Diseases, 2020
Background Procalcitonin is an inflammatory biomarker that is sensitive for bacterial infections and a promising clinical decision aid in antimicrobial stewardship programs.
Ingrid Christensen, Jon Birger Haug, Dag Berild, Jørgen Vildershøj Bjørnholt, Lars-Petter Jelsness-Jørgensen   +4 more
doaj   +1 more source

Evaluation of the Relationship Between C-reactive Protein, Lactate, Procalcitonin and Albumin Levels and Procalcitonin/Albumin Ratio with SOFA and APACHE-II Scores in Emergency ICU Patients

Eurasian Journal of Emergency Medicine, 2020
Aim:This study aimed to investigate the efficacy of C-reactive protein (CRP), lactate, procalcitonin and albumin levels and procalcitonin/ albumin ratio used as indicators of infection on mortality in critical patients admitted to the intensive care unit
Dilek Atik, Başar Cander, Bensu Bulut, Hilmi Kaya, Ramiz Yazıcı, Tuba Öztürk Demir, Ramazan Güven   +6 more
doaj   +1 more source

Procalcitonin levels in maternal serum and cord blood as marker for diagnosis of early onset neonatal sepsis

European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2023
Objectives: To assess the diagnostic accuracy of Procalcitonin in maternal serum and umbilical cord blood samples to predict Early onset neonatal sepsis (EONS). Study Design: It was a Prospective analytical cohort study.
Puja Yadav, Kavita Agarwal, Anita Rani, Rupali Dewan, Harish Chellani   +4 more
doaj   +1 more source

Ability of procalcitonin to discriminate infection from non-infective inflammation using two pleural disease settings.

PLoS ONE, 2012
UnlabelledProcalcitonin has been shown to be useful in separating infection from non-infective disorders. However, infection is often paralleled by tissue inflammation.
Fiona J McCann, Stephen J Chapman, Wai Cho Yu, Nick A Maskell, Robert J O Davies, Y C Gary Lee   +5 more
doaj   +1 more source

PROFILE OF PROCALCITONIN LEVELS IN SEVERE–CRITICAL COVID-19 PATIENTS [PDF]

, 2021
The diagnostic and therapeutic modalities of COVID-19 are still being researched and developed. One of the diagnostic modalities in the treatment of COVID-19, especially in patients with severe and critical symptoms, is procalcitonin.
Room, Asyikun Nasyid, Muchtar, Faisal, Amin, Hisbullah   +2 more
core   +1 more source

Procalcitonin-guided antibiotic therapy algorithms for different types of acute respiratory infections based on previous trials

, 2018
Introduction: Although evidence indicates that use of procalcitonin to guide antibiotic decisions for the treatment of acute respiratory infections (ARI) decreases antibiotic consumption and improves clinical outcomes, algorithms used within studies had ...
Rodrigo O. Deliberato (5512706), Meret Merker (5512694), Konrad Reinhart (51097), Yahya Shehabi (51763), Michael Tamm (65010), Matthias Briel (120543), Beat Mueller (300968), Michel Wolff (147901), Philipp Schuetz (33688), Rebekka Bolliger (5512691), Maarten Nijsten (3477845), Charles E Luyt (5512697), Angela Branche (5512703), Bianca Beghé (482635), Stefan Schroeder (5512685), Alessia Verduri (482636), Vandack Nobre (4175917), Mirjam Christ-Crain (15611), Evelien de Jong (5512688), Jens-Ulrik S. Jensen (5512700), Pierre Damas (20576), Bin Cao (186972), Daiana Stolz (65007), Tobias Welte (87188), Albertus Beishuizen (70118)   +24 more
core   +1 more source

Relationship Between CRP, Procalcitonin, I/T Ratio and The Incidence of Sepsis in Children

, 2023
Background: Sepsis is body immune response due to infection. Sepsis is a medical emergency condition with high-risk of mortality. WHO in 2018 stated that every year there were 2.9 million cases of death due to sepsis.
Edward Kurnia Setiawan LIMIJADI, Galuh HARDANINGSIH, Nahwa ARKHAESI, Nissa Salsabila WINARNO, MULYONO   +4 more
core   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source