Results 61 to 70 of about 4,305,606 (328)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

SAT Modulo Monotonic Theories

open access: yes, 2014
We define the concept of a monotonic theory and show how to build efficient SMT (SAT Modulo Theory) solvers, including effective theory propagation and clause learning, for such theories.
Bayless, Noah   +3 more
core   +1 more source

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Shortest Walk in a Dungeon Graph

open access: yesProceedings of the International Florida Artificial Intelligence Research Society Conference
With games like No Man’s Sky and Diablo IV, procedural generation of content in games is ever-increasing. Heuristics are needed to assess the goodness of generated content.
Christopher Durham, Chris Alvin
doaj   +1 more source

Procedural Generation of Artistic Patterns Using a Modified Orbit Trap Method

open access: yesApplied Sciences, 2022
In the literature, we can find various methods for generating artistic patterns. One of the methods is the orbit trap method. In this paper, we propose various modifications of a variant of the orbit trap method that generates patterns with wallpaper ...
Krzysztof Gdawiec, Hezekiah Adewinbi
doaj   +1 more source

AutoBiomes: procedural generation of multi-biome landscapes

open access: yesThe Visual Computer, 2020
Advances in computer technology and increasing usage of computer graphics in a broad field of applications lead to rapidly rising demands regarding size and detail of virtual landscapes.
Roland Fischer   +3 more
semanticscholar   +1 more source

Introducing new constructs for data modelling and column generation in LP modelling languages [PDF]

open access: yes, 1993
Through popular implementation of structured query language (SQL) and query-by-example(QBE) relational databases have become the de-facto industry standard for data modelling.We consider the indices, sets, and the declarative form of Linear Programming ...
Kristjansson, B   +3 more
core  

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

Towards Urban Digital Twins: A Workflow for Procedural Visualization Using Geospatial Data

open access: yesRemote Sensing
A key feature for urban digital twins (DTs) is an automatically generated detailed 3D representation of the built and unbuilt environment from aerial imagery, footprints, LiDAR, or a fusion of these.
Sanjay Somanath   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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