Results 161 to 170 of about 2,842 (177)

Proline dehydrogenase gene (PRODH) polymorphisms and schizophrenia susceptibility: a meta-analysis

Metabolic Brain Disease, 2017
Previous studies have been conducted to explore the association between proline dehydrogenase gene (PRODH) polymorphisms and schizophrenia (SZ) susceptibility, but providing the controversial results. Here we performed this meta-analysis to determine whether PRODH variants were associated with SZ risk.
Xingzhi, Guo, Peng, Tang, Caiping, Yang, Rui, Li   +3 more
openaire   +2 more sources

A Risk PRODH Haplotype Affects Sensorimotor Gating, Memory, Schizotypy, and Anxiety in Healthy Male Subjects

Biological Psychiatry, 2009
Significant associations have been shown for haplotypes comprising three PRODH single nucleotide polymorphisms (SNPs; 1945T/C, 1766A/G, 1852G/A) located in the 3' region of the gene, suggesting a role of these variants in the etiopathogenesis of schizophrenia.
Stella Giakoumaki, Panos Roussos, Panos Bitsios   +2 more
exaly   +3 more sources

Schizophrenia-like neurophysiological abnormalities in 22q11.2 deletion syndrome and their association to COMT and PRODH genotypes

Journal of Psychiatric Research, 2013
22q11.2 deletion syndrome (22q11.2DS) is a common genetic risk factor for the development of schizophrenia. We investigated two neurophysiological endophenotypes of schizophrenia - P50 sensory gating and mismatch negativity in 22q11.2DS subject and evaluated their association with catechol O-methyltransferase (COMT) and proline dehydrogenase (PRODH ...
Omer, Zarchi, Miri, Carmel, Chen, Avni, Josef, Attias, Amos, Frisch, Elena, Michaelovsky, Miriam, Patya, Tamar, Green, Ronnie, Weinberger, Abraham, Weizman, Doron, Gothelf   +10 more
openaire   +2 more sources

Association of COMT and PRODH gene variants with intelligence quotient (IQ) and executive functions in 22q11.2DS subjects

Journal of Psychiatric Research, 2014
The 22q11.2 deletion syndrome (22q11.2DS) carries the highest genetic risk factor for the development of schizophrenia. We investigated the association of genetic variants in two schizophrenia candidate genes with executive function (EF) and IQ in 22q11.2DS individuals.
Miri, Carmel, Omer, Zarchi, Elena, Michaelovsky, Amos, Frisch, Miriam, Patya, Tamar, Green, Doron, Gothelf, Abraham, Weizman   +7 more
openaire   +2 more sources

Identification of PRODH mutations in Korean neonates with type I hyperprolinemia.

Annals of clinical and laboratory science, 2013
Hyperprolinemia is a rare inherited metabolic disorder characterized by a high proline level in blood and/or urine and various neuropsychiatric symptoms. Type I hyperprolinemia is caused by a proline oxidase deficiency, which is encoded by the PRODH gene on chromosome 22q11.
Mi-Ae, Jang, Byung Cheol, Kim, Chang-Seok, Ki, Soo-Youn, Lee, Jong-Won, Kim, Tae Youn, Choi, Dong Hwan, Lee, Junghan, Song, Yong-Wha, Lee, Hyung-Doo, Park   +9 more
openaire   +1 more source

Proline Intake Dampens Radiosensitivity in Prostate Cancer Cells by Targeting PRODH/MAPK Pathway

Radiation Research
Radiotherapy remains a standard treatment for prostate cancer (PCa), inducing tumor cell death and apoptosis. However, its efficacy depends on various factors, including tumor cell metabolism. In this study, we investigated whether alterations in proline metabolism influence the response of prostate cancer cells to radiation.
Lei, Chang, Xinzhou, Deng, Shan, Jiang, Cangyu, Wang, Jingjing, Chai, Le, Zhou, Chao, Tian, Yuanhui, Tang, Zhiguo, Luo, Lihua, Duan, Yutao, Yan   +10 more
openaire   +2 more sources

Failure to find association between PRODH deletion and schizophrenia

Schizophrenia Research, 2004
Tsuyuka, Ohtsuki, Syunsuke, Tanaka, Hiroki, Ishiguro, Emiko, Noguchi, Tadao, Arinami, Ei-ichi, Tanabe, Kazuo, Yara, Tatsunobu, Okubo, Sakae, Takahashi, Masato, Matsuura, Tei-ichiro, Sakai, Mariko, Muto, Takuya, Kojima, Eisuke, Matsushima, Michio, Toru, Toshiya, Inada   +15 more
openaire   +2 more sources

Importance of COMT and PRODH in psychosis development

Nature Clinical Practice Neurology, 2006
openaire   +1 more source

Proline dehydrogenase 1 (PRODH; POX)

Science-Business eXchange, 2012
openaire   +1 more source

Differential control and function of Arabidopsis ProDH1 and ProDH2 genes on infection with biotrophic and necrotrophic pathogens

Molecular Plant Pathology, 2017
Maria Elena Alvarez, Nicolas MIGUEL Cecchini, Georgina Fabro   +2 more
exaly