Proline metabolic reprogramming modulates cardiac remodeling induced by pressure overload in the heart. [PDF]
Lv Q +10 more
europepmc +1 more source
Proline dehydrogenase, a rate-limiting catabolic enzyme, affecting the growth and pathogenicity of Toxoplasma gondii tachyzoites by regulating the proline metabolism and mitochondrial function of the parasite. [PDF]
Geng XL +9 more
europepmc +1 more source
Screening a knowledge-based library of low molecular weight compounds against the proline biosynthetic enzyme 1-pyrroline-5-carboxylate 1 (PYCR1). [PDF]
Meeks KR, Bogner AN, Tanner JJ.
europepmc +1 more source
Related searches:
PRODH variants and risk for schizophrenia
Amino Acids, 2008Schizophrenia is a common, devastating neuropsychiatric disorder whose etiology is largely unknown. Multiple studies in humans and in mouse and fly models suggest a role for proline and PRODH, the gene encoding the first enzyme in the pathway of proline catabolism, in contributing risk for schizophrenia.
David Valle
exaly +3 more sources
Context of action of Proline Dehydrogenase (ProDH) in the Hypersensitive Response of Arabidopsis [PDF]
La proline (Pro) déshydrogénase (ProDH) potentialise l'éclatement oxydatif et la mort cellulaire de la réponse hypersensible (RH) de la plante par des mécanismes non encore élucidés. ProDH convertit Pro en ∆1 pyrroline-5-carboxylate (P5C) et peut agir conjointement avec la P5C déshydrogénase (P5CDH) pour produire Glu, ou avec la P5C réductase (P5CR ...
Mariela Ines Monteoliva +2 more
exaly +4 more sources
PRODH gene is associated with executive function in schizophrenic families
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2007AbstractThe aim of this study was to investigate the relationship between polymorphisms in the PRODH and COMT genes and selected neurocognitive functions. Six SNPs in PRODH and two SNPs in COMT were genotyped in 167 first‐episode schizophrenic families who had been assessed by a set of 14 neuropsychological tests.
Li, T +9 more
openaire +5 more sources
Cognitive impairment in schizophrenia (SCZ) is a core feature, relevant for the disease prognosis and functional capacity of the patients. It has also been identified as an endophenotype and proposed as a genetic mechanism of risk for schizophrenia.We aimed to evaluate the association of genetic variants in COMT, PRODH, and DISC1 with the cognitive ...
Ingrid Fricke-Galindo +8 more
openaire +2 more sources
Early neurological phenotype in 4 children with biallelic PRODH mutations
Brain and Development, 2007Hyperprolinemia type I (HPI) results from a deficiency of proline oxidase (POX), involved in the first step in the conversion of proline to glutamate. Diverse phenotypes were described in patients with HPI, prior to the identification of the POX gene (PRODH): whereas various patients were asymptomatic, others had neurological and extraneurological ...
Alexandra, Afenjar +12 more
exaly +3 more sources

