Results 11 to 20 of about 3,837,675 (312)

Influence of ABCB1 3435C>T polymorphism on methotrexate safety in patients with psoriasis [PDF]

Vestnik Dermatologii i Venerologii, 2023
Background. Methotrexate is a highly effective systemic treatment for moderate to severe psoriasis, but drug toxicity may limit its use. Recent evidence suggests that it is necessary to take into account the individual characteristics of methotrexate ...
Alexey A. Kubanov, Anastasiia V. Asoskova, Michael S. Zastrozhin, Zhannet A. Sozaeva, Dmitry A. Sychev   +4 more
doaj   +1 more source

Insulin resistance and its role in the pathogenesis of pre-diabetes development in obese adolescents

Consilium Medicum, 2023
Background. The prevalence of childhood obesity has increased significantly over the past three decades worldwide, and in this regard, the frequency of diseases associated with obesity, including disorders of carbohydrate metabolism, has increased.
Nadezhda B. Min'kova, Oleg Iu. Latyshev, Goar F. Okminyan, Elena V. Kiseleva, Dar'ia S. Romaikina, Liubov N. Samsonova   +5 more
doaj   +1 more source

Problematising parent–professional partnerships in education [PDF]

, 2008
The value of, and need for, parent–professional partnerships is an unchallenged mantra within policy relating to ‘special educational needs’. In spite of this, partnerships continue to be experienced as problematic by both parents and professionals. This
Audit Commission, Cole B.A., Department for Education and Skills (DfES), Department for Education and Skills (DfES), Department for Education and Skills (DfES), Department for Education and Skills and Department of Health (DfES and DH), Department of Education and Science (DES), Department of Health, Department of Health and Department for Education and Skills (DH and DfES), Dockrell J., Foucault M., Fulcher G., Hodge N., Hornby G., Hunt M., Independent Panel for Special Education Advice (IPSEA), James A., Katherine Runswick‐Cole, Mackenzie C., Martin J., Nick Hodge, Read J., Runswick‐Cole K., Schall C., Seligman M., Simmons K., Solity J., Swain J., Warmington P., Watson N., White C., Woodcock J.   +31 more
core   +2 more sources

CYP2D6 gene polymorphic markers role in determining the optimal treatment tactics for portal hypertension in patients with liver cirrhosis

Терапевтический архив, 2022
Aim. To study the polymorphic markers CYP2D6*4 (G1846A, rs3892097), CYP2D6*6 (T1707del, rs5030655), CYP2D6*10 (C100T, rs1065852), CYP2D6*41 (G2988A, rs28371725) and CYP2D6*3 (A2549del, rs4986774) role in treatment optimization of portal hypertension with
Dmitry A. Sychev, Andrei I. Parusov, Irina D. Loranskaya, Natalia P. Denisenko, Kristina A. Akmalova, Zhannet A. Sozaeva, Olga L. Turkina, Michael S. Zastrozhin   +7 more
doaj   +1 more source

Effect of combination antihypertensive therapy, including renin-angiotensin-aldosterone system inhibitors, on oxidative stress and arterial remodeling in hypertensive patients with heart failure with preserved ejection fraction

Российский кардиологический журнал, 2021
Aim. To study the effect of triple combination therapy on oxidative stress and arterial remodeling in hypertensive patients with heart failure with preserved ejection fraction (HFpEF).Material and methods.
Z. M. Akhilgova, A. P. Roitman, N. G. Rakova, A. V. Bugrov, E. A. Pavlovskaya, M. S. Zastrozhin, A. G. Avtandilov   +6 more
doaj   +1 more source

Treatment of fever in acute upper respiratory tract infections in children

Медицинский совет, 2022
Introduction. The WHO recommends using acetaminophen (paracetamol) and ibuprofen in fever treatment in children and does not recommend their use in sequence to avoid overdose.
I. N. Zakharova, I. V. Berezhnaya, N. G. Sugyan, T. M. Tvorogova, D. S. Kolushkin, V. V. Pupykina, I. A. Rodionov   +6 more
doaj   +1 more source

Study of the Effect of Polymorphic Markers of the NAT2 Gene on the Risk of Adverse Drug Reactions in Patients with Pulmonary Tuberculosis Who Received Isoniazid and Rifampicin

Безопасность и риск фармакотерапии, 2021
Tuberculosis remains one of the most dangerous and widespread infectious diseases. More than 20 medicinal products are currently available for the treatment of tuberculosis.
A. A. Kachanova, Yu. A. Pimenova, G. N. Shuev, K. A. Akmalova, Zh. A. Sozaeva, N. M. Krasnova, E. A. Grishina, D. A. Sychev   +7 more
doaj   +1 more source

Is high normotension a norm or a risk factor for perinatal complications: prospective cohort study [PDF]

Consilium Medicum, 2022
Aim. Comparative assessment of the effect of high normotension and hypertension 12nd stage on the risk of gestational and perinatal complications. Materials and methods.
Natalia M. Podzolkova, Margarita Y. Skvortsova, Yulia V. Denisova, Tatiana V. Denisova   +3 more
doaj   +1 more source

The differential diagnosis algorithm of ovarian tumors in reproductive patients: a prospective study [PDF]

Гинекология, 2022
Aim. The aim of the study was to evaluate the efficiency of different methods of preoperative diagnostics and to develop an algorithm for examining patients of reproductive age with ovarian tumors. Materials and methods.
Natalia M. Podzolkova, Vasilii В. Osadchev, Kirill V. Babkov, Natalia E. Safonova   +3 more
doaj   +1 more source

The pharmacogenetics of hypoglycemia and the glycemic variability at the patients ith type 2 diabetes mellitus

Терапевтический архив, 2020
Aim.To investigate the link between the hypoglycemia (registrated accurately by the professional Continuous Glucose Monitoring CGM; severe hypoglycemia at home) and the hetero-/homozygote carriage of single nucleotide polymorphisms (SNP) of cytochrome ...
N. A. Chernikova, L. L. Kamynina, A. S. Ametov, D. A. Sychev, E. A. Grishina, K. A. Ryzhikova   +5 more
doaj   +1 more source