Results 21 to 30 of about 642,156 (268)

CYP2C8, PTGS-1, 2 gene polymorphisms prevalence associated with sensitivity to non-steroidal anti-inflammatory drugs among North Caucasus ethnic groups

Терапевтический архив, 2021
Aim. Find the prevalence of CYP2C8*3 (rs10509681; rs11572080), PTGS-1 (rs10306135; rs12353214) and PTGS-2 (rs20417) alleles and genotypes in four ethnic groups among Laks, Avars, Dargins and Kumyks. Materials and methods.
Sherzod P. Abdullaev, Natalia P. Denisenko, Karin B. Mirzaev, Gregorii N. Shuev, Zhannet A. Sozaeva, Anastasia A. Kachanova, Suleiman N. Mammaev, Elvira A. Kasaeva, Danial M. Gafurov, Elena A. Grishina, Dmitry A. Sychev   +10 more
doaj   +1 more source

CYP2D6 gene polymorphic markers role in determining the optimal treatment tactics for portal hypertension in patients with liver cirrhosis

Терапевтический архив, 2022
Aim. To study the polymorphic markers CYP2D6*4 (G1846A, rs3892097), CYP2D6*6 (T1707del, rs5030655), CYP2D6*10 (C100T, rs1065852), CYP2D6*41 (G2988A, rs28371725) and CYP2D6*3 (A2549del, rs4986774) role in treatment optimization of portal hypertension with
Dmitry A. Sychev, Andrei I. Parusov, Irina D. Loranskaya, Natalia P. Denisenko, Kristina A. Akmalova, Zhannet A. Sozaeva, Olga L. Turkina, Michael S. Zastrozhin   +7 more
doaj   +1 more source

Effect of combination antihypertensive therapy, including renin-angiotensin-aldosterone system inhibitors, on oxidative stress and arterial remodeling in hypertensive patients with heart failure with preserved ejection fraction

Российский кардиологический журнал, 2021
Aim. To study the effect of triple combination therapy on oxidative stress and arterial remodeling in hypertensive patients with heart failure with preserved ejection fraction (HFpEF).Material and methods.
Z. M. Akhilgova, A. P. Roitman, N. G. Rakova, A. V. Bugrov, E. A. Pavlovskaya, M. S. Zastrozhin, A. G. Avtandilov   +6 more
doaj   +1 more source

PROFESSIONALISM, PROFESSIONALITY AND THE DEVELOPMENT OF EDUCATION PROFESSIONALS [PDF]

British Journal of Educational Studies, 2008
ABSTRACT: What purpose is served by renovation or redesign of professionalism, and how successful a process is it likely to be? This article addresses these questions by examining the effectiveness as a professional development mechanism of the imposition of changes to policy and/or practice that require modification or renovation of professionalism ...
openaire   +4 more sources

Treatment of fever in acute upper respiratory tract infections in children

Медицинский совет, 2022
Introduction. The WHO recommends using acetaminophen (paracetamol) and ibuprofen in fever treatment in children and does not recommend their use in sequence to avoid overdose.
I. N. Zakharova, I. V. Berezhnaya, N. G. Sugyan, T. M. Tvorogova, D. S. Kolushkin, V. V. Pupykina, I. A. Rodionov   +6 more
doaj   +1 more source

Study of the Effect of Polymorphic Markers of the NAT2 Gene on the Risk of Adverse Drug Reactions in Patients with Pulmonary Tuberculosis Who Received Isoniazid and Rifampicin

Безопасность и риск фармакотерапии, 2021
Tuberculosis remains one of the most dangerous and widespread infectious diseases. More than 20 medicinal products are currently available for the treatment of tuberculosis.
A. A. Kachanova, Yu. A. Pimenova, G. N. Shuev, K. A. Akmalova, Zh. A. Sozaeva, N. M. Krasnova, E. A. Grishina, D. A. Sychev   +7 more
doaj   +1 more source

Is high normotension a norm or a risk factor for perinatal complications: prospective cohort study [PDF]

Consilium Medicum, 2022
Aim. Comparative assessment of the effect of high normotension and hypertension 12nd stage on the risk of gestational and perinatal complications. Materials and methods.
Natalia M. Podzolkova, Margarita Y. Skvortsova, Yulia V. Denisova, Tatiana V. Denisova   +3 more
doaj   +1 more source

The pharmacogenetics of hypoglycemia and the glycemic variability at the patients ith type 2 diabetes mellitus

Терапевтический архив, 2020
Aim.To investigate the link between the hypoglycemia (registrated accurately by the professional Continuous Glucose Monitoring CGM; severe hypoglycemia at home) and the hetero-/homozygote carriage of single nucleotide polymorphisms (SNP) of cytochrome ...
N. A. Chernikova, L. L. Kamynina, A. S. Ametov, D. A. Sychev, E. A. Grishina, K. A. Ryzhikova   +5 more
doaj   +1 more source

The differential diagnosis algorithm of ovarian tumors in reproductive patients: a prospective study [PDF]

Гинекология, 2022
Aim. The aim of the study was to evaluate the efficiency of different methods of preoperative diagnostics and to develop an algorithm for examining patients of reproductive age with ovarian tumors. Materials and methods.
Natalia M. Podzolkova, Vasilii В. Osadchev, Kirill V. Babkov, Natalia E. Safonova   +3 more
doaj   +1 more source

Structure of the distribution of genetic determinants of the efficacy and safety of non-steroidal anti-inflammatory drugs in the Russian population: focus on CYP2C8, PTGS1 and PTGS2

Современная ревматология, 2022
The efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) may be determined by the polymorphic nature of the CYP2C8, PTGS1 and PTGS2 genes.Objective: to analyze the nature of the distribution of CYP2C8*3 (rs10509681), CYP2C8*3 (rs11572080)
N. P. Denisenko, Sh. P. Abdullaev, K. A. Akmalova, Zh. A. Sozaeva, A. A. Kachanova, M. S-Kh. Sozaeva, L. Z. Bolieva, E. A. Grishina, D. A. Sychev   +8 more
doaj   +1 more source