Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
A prática do bom professor de Educação Física na perspectiva dos alunos do ensino médio
Revista Brasileira de Estudos PedagógicosAnalisa a prática pedagógica do docente de Educação Física considerado bom professor na perspectiva dos alunos do ensino médio. A partir de uma investigação de campo descritiva e de cunho qualitativo com um grupo amostral composto por professores ...
Jaqueline Aparecida de Souza +1 more
doaj +1 more source
Failing or Prevailing? Russian Educational Discourse in the Israeli Academic Classroom
Open Cultural Studies, 2023 This article seeks to explore the ways in which Russian–Soviet educational discourse survives in Israeli universities by bringing its underlying cultural messages to Israeli students. It focuses on the interpretation of educational discursive perceptions
Zbenovich Claudia
doaj +1 more source
Internal Consistency and Reliability of the Networked Minds\ud Measure of Social Presence [PDF]
, 2004 This study sought to develop and test a measure\ud of social presence. Based on review of current\ud definitions and measures, a synthesis of the\ud theoretical construct that meets the criteria and\ud dimensions [1] is proposed for a broad successful ...
Biocca, Professor Frank +1 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
O docente “em falta” como figura cristalizada
Estilos da Clínica, 2017 Uma das figuras docentes que os discursos pedagógicos produziram no Brasil, no âmbito da educação básica, e que nas últimas décadas tende a prevalecer, é a do docente que deve ser orientado em seu pensamento e ação educativa por especialistas de ordem ...
Daniel Revah
doaj +1 more source
Networked Minds Social Presence Inventory:\ud |(Scales only, Version 1.2)\ud Measures of co-presence, social presence,\ud subjective symmetry, and intersubjective symmetry [PDF]
, 2003 This document includes all the items that comprise the Networked Minds Social Presence Inventory. For more information on the scale, please consult the Guide to the Networked Minds Inventory on this ...
Biocca, Professor Frank +1 more
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Nonlinear Models of Neural and Genetic Network Dynamics:\ud \ud Natural Transformations of Łukasiewicz Logic LM-Algebras in a Łukasiewicz-Topos as Representations of Neural Network Development and Neoplastic Transformations \ud [PDF]
, 2011 A categorical and Łukasiewicz-Topos framework for Algebraic Logic models of nonlinear dynamics in complex functional systems such as Neural Networks, Cell Genome and Interactome Networks is introduced.
Baianu, Professor I.C.
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source