Results 41 to 50 of about 6,335,661 (316)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Abortion and Moral Repugnancy [PDF]

open access: yes, 2006
Most arguments concerning abortion center around the issue of rights. This short essay argues that there can be important considerations regarding the matter that have nothing whatsoever to do with rights.
Thomas, Professor Laurence
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Professional and Personal Traits of a Professor: A Study on Filipino Students' Preferences

open access: yesUniversal Journal of Educational Research, 2023
Schools have resumed receiving students after more than two years of closing doors to learners. College students. Students have built preferences on their professors even before the pandemic began.
Jayrome L. Nuñez, Louie P. Gula
doaj   +1 more source

Variables, Generality and Existence: considerations on the notion of a concept-script [PDF]

open access: yes, 2005
A defense of the Frege / Russell idea of logic as a 'concept=script' or 'ideal language', and a discussion of the relationship of this project to the formalisation of mass nouns or non-count ...
Laycock, Professor Henry
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Evaluation of the Readiness for E-Learning from the Viewpoints of the Students and Professors of Allameh Tabataba’i University [PDF]

open access: yesInterdisciplinary Journal of Virtual Learning in Medical Sciences, 2016
Introduction : Achieving e-learning requires a comprehensive study on different aspects of e-learning readiness. The present study aimed to evaluate the readiness for e-learning from the viewpoints of the students as well as faculty members of Allameh ...
Esmaeil Aslani   +3 more
doaj   +1 more source

Complexity over Uncertainty in Generalized Representational\ud Information Theory (GRIT): A Structure-Sensitive General\ud Theory of Information [PDF]

open access: yes, 2013
What is information? Although researchers have used the construct of information liberally to refer to pertinent forms of domain-specific knowledge, relatively few have attempted to generalize and standardize the construct.
Vigo, Professor Ronaldo
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Self-Esteem at University: Proposal of an Artificial Neural Network Based on Resilience, Stress, and Sociodemographic Variables

open access: yesFrontiers in Psychology, 2022
Artificial intelligence (AI) is a useful predictive tool for a wide variety of fields of knowledge. Despite this, the educational field is still an environment that lacks a variety of studies that use this type of predictive tools.
Juan Pedro Martínez-Ramón   +3 more
doaj   +1 more source

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