Results 1 to 10 of about 333,594 (247)

Characterization of The Retinal Progenitor Cells Generated Using Co-Culture Systems [PDF]

Cell Journal, 2022
Objective: Degeneration of the photoreceptors due to retinal disorders can affect vision, and even lead to blindness. Recently therapeutic progress in retinal degeneration, using human embryonic stem cells (hESCs), has been facing technical challenges,
Sara Momenzadeh, Fereshteh Karamali, Atefeh Atefi, Mohammad Hossein Nasr-Esfahani   +3 more
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Triple-hit explanation for the worse prognosis of pediatric acute lymphoblastic leukemia among Mexican and Hispanic children

Frontiers in Oncology, 2022
Acute lymphoblastic leukemia (ALL) is the most common malignancy among Mexican and Hispanic children and the first cause of death by disease in Mexico. We propose a “triple-hit” explanation for the survival gap affecting this population.
Roberto Rivera-Luna, Roberto Rivera-Luna, Patricia Perez-Vera, Cesar Galvan-Diaz, Liliana Velasco-Hidalgo, Alberto Olaya-Vargas, Rocio Cardenas-Cardos, Marco Aguilar-Ortiz, Jesus Ponce-Cruz   +8 more
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Categorisation of patients based on immune profiles: a new approach to identifying candidates for response to checkpoint inhibitors

Clinical & Translational Immunology, 2021
Objectives Inhibitors to the checkpoint proteins cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) and programmed cell death protein 1 (PD‐1) are becoming widely used in cancer treatment.
Svetlana Bornschlegl, Michael P Gustafson, Danae A Delivanis, Mabel Ryder, Minetta C Liu, George Vasmatzis, Chris L Hallemeier, Sean S Park, Lewis R Roberts, Ian F Parney, Diane F Jelinek, Allan B Dietz   +11 more
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Hematopoiesis Remains Permissive to Bone Marrow Transplantation After Expansion of Progenitors and Resumption of Blood Cell Production

Frontiers in Cell and Developmental Biology, 2021
The immense regenerative power of hematopoietic tissue stems from the activation of the immature stem cells and the progenitor cells. After partial damage, hematopoiesis is reconstituted through a period of intense regeneration when blood cell production
Martin Báječný, Martin Báječný, Chia-Ling Chen, Kateřina Faltusová, Tomáš Heizer, Tomáš Heizer, Katarína Szikszai, Petr Páral, Petr Páral, Luděk Šefc, Emanuel Nečas   +10 more
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Brain isoform glycogen phosphorylase as a novel hepatic progenitor cell marker. [PDF]

PLoS ONE, 2015
An appropriate liver-specific progenitor cell marker is a stepping stone in liver regenerative medicine. Here, we report brain isoform glycogen phosphorylase (GPBB) as a novel liver progenitor cell marker.
Yu-Wen Huang, Chien-Chang Chiu, Ja-Der Liang, Ling-Ling Chiou, Guan-Tarn Huang, Ming-Jiun Yu, Hsuan-Shu Lee   +6 more
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Stable human cartilage progenitor cell line stimulates healing of meniscal tears and attenuates post-traumatic osteoarthritis

Frontiers in Bioengineering and Biotechnology, 2022
Meniscal tearing in the knee increases the risk of post-traumatic osteoarthritis (OA) in patients. The therapeutic application of tissue-specific mesenchymal progenitor cells is currently being investigated as an emerging biologic strategy to help ...
Salomi Desai, Mark Dooner, Jake Newberry, John Twomey-Kozak, Janine Molino, Jay Trivedi, Jay M. Patel, Brett D. Owens, Chathuraka T. Jayasuriya   +8 more
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Hindlimb Immobilization Increases IL-1β and Cdkn2a Expression in Skeletal Muscle Fibro-Adipogenic Progenitor Cells: A Link Between Senescence and Muscle Disuse Atrophy

Frontiers in Cell and Developmental Biology, 2022
Loss of muscle mass and strength contributes to decreased independence and an increased risk for morbidity and mortality. A better understanding of the cellular and molecular mechanisms underlying muscle atrophy therefore has significant clinical and ...
Emily Parker, Andrew Khayrullin, Andrew Kent, Bharati Mendhe, Khairat Bahgat Youssef El Baradie, Khairat Bahgat Youssef El Baradie, Kanglun Yu, Jeanene Pihkala, Yutao Liu, Meghan McGee-Lawrence, Maribeth Johnson, Jie Chen, Mark Hamrick   +12 more
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Formaldehyde Fixation of Extracellular Matrix Protein Layers for Enhanced Primary Cell Growth

Bio-Protocol, 2017
Coating tissue culture vessels with the components of the extracellular matrix such as fibronectin and collagens provides a more natural environment for primary cells in vitro and stimulates their proliferation.
Natalia Andreeva, Alexander Belyavsky
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Isolation and Expansion of Mesenchymal Stem Cells from Murine Adipose Tissue

Bio-Protocol, 2017
Mesenchymal stem cells (MSCs) are currently intensively studied due to significant promise which they represent for successful implementations of future cell therapy clinical protocols. This in turn emphasizes importance of careful preclinical studies of
Natalia Andreeva, Alexandra Dalina, Alexander Belyavsky   +2 more
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Nuclear GSK-3β and Oncogenic KRas Lead to the Retention of Pancreatic Ductal Progenitor Cells Phenotypically Similar to Those Seen in IPMN

Frontiers in Cell and Developmental Biology, 2022
Glycogen synthase kinase-3β (GSK-3β) is a downstream target of oncogenic KRas and can accumulate in the nucleus in pancreatic ductal adenocarcinoma (PDA).
Li Ding, Kaely Roeck, Cheng Zhang, Brooke Zidek, Esther Rodman, Yasmin Hernandez-Barco, Jin-San Zhang, Jin-San Zhang, William Bamlet, Ann Oberg, Lizhi Zhang, Nabeel Bardeesy, Hu Li, Daniel Billadeau   +13 more
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