Results 11 to 20 of about 595,486 (312)

Hepatic progenitor cells from adult human livers for cell transplantation. [PDF]

, 2008
Objective: Liver regeneration is mainly based on cellular self-renewal including progenitor cells. Efforts have been made to harness this potential for cell transplantation, but shortage of hepatocytes and premature differentiated progenitor cells ...
Aurich, H., Brockhoff, G., Christ, B., Jauch, Karl-Walter, Kirchner, S., Kunz-Schughart, L.A., Lichtenauer, M., Schlitt, H.-J., Stock, P., Thasler, Wolfgang E., Weiss, T.S.   +10 more
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Isolation and Expansion of Mesenchymal Stem Cells from Murine Adipose Tissue

Bio-Protocol, 2017
Mesenchymal stem cells (MSCs) are currently intensively studied due to significant promise which they represent for successful implementations of future cell therapy clinical protocols. This in turn emphasizes importance of careful preclinical studies of
Natalia Andreeva, Alexandra Dalina, Alexander Belyavsky   +2 more
doaj   +1 more source

Cell Therapy for Anal Sphincter Incontinence: Where Do We Stand?

Cells, 2021
Anal sphincter incontinence is a chronic disease, which dramatically impairs quality of life and induces high costs for the society. Surgery, considered as the best curative option, shows a disappointing success rate.
Alexandre Balaphas, Jeremy Meyer, Raphael P. H. Meier, Emilie Liot, Nicolas C. Buchs, Bruno Roche, Christian Toso, Leo H. Bühler, Carmen Gonelle-Gispert, Frédéric Ris   +9 more
doaj   +1 more source

Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. [PDF]

, 2018
The mammary epithelium depends on specific lineages and their stem and progenitor function to accommodate hormone-triggered physiological demands in the adult female.
Abe, Akalin, Alison E. Casey, Ankit Sinha, Asselin-Labat, Buenrostro, Cardiff, Cerami, Cheryl Arrowsmith, Chlebowski, Cox, Cox, Dalia Barsyte-Lovejoy, Daniel De Carvalho, Deugnier, Dos Santos, Edgar, Eirew, Eirew, Eisen, Erik Drysdale, Gary Bader, Gascard, Genevieve Deblois, Gu, Hal Berman, Heinz, Hennighausen, Herschkowitz, Hu, Hui Fang, Huston, Hyeyeon Kim, Ignatchenko, Jackson, Jennifer Cruickshank, Joshi, Joshi, Joshi, Julie Livingstone, Kaltenborn, Kauff, Kelsey, Kendrick, Kiechl, Kislinger, Koboldt, Kotsopoulos, Krueger, Kucera, Labarge, Li, Lim, Lim, Lin, Loenen, Lucas, Lydon, Marotti, Maruyama, Mathieu Lupien, McLean, Meissner, Merico, Michailidou, Michalak, Mohammed, Molyneux, Mona Shehata, Nguyen, Pal, Pathania, Paul C. Boutros, Paul Waterhouse, Pei, Pellacani, Pirashaanthy Tharmapalan, Rajat Singhania, Rama Khokha, Reimand, Rios, Rios, Rugg-Gunn, Ruth Isserlin, Schimanski, Shackleton, Shannon, Shehata, Shiah, Shu, Sigl, Smith, Smyth, Stefan Hofer, Stefan Knapp, Stingl, Storey, Stunnenberg, Subramanian, Swneke Bailey, Thomas Kislinger, Tiago Medina, Tomasetti, van Amerongen, Van Keymeulen, Van Keymeulen, Visvader, Wang, Wojtowicz, Wuidart, Yu-Jia Shiah, Zhang   +111 more
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Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate. [PDF]

, 2017
Adult stem cells commonly give rise to transit-amplifying progenitors, whose progeny differentiate into distinct cell types. It is unclear if stem cell niche signals coordinate fate decisions within the progenitor pool.
Burrous, Haley, Dai, Wei, Kenney, Thomas, Montell, Denise J, Peterson, Amy   +4 more
core   +2 more sources

Endothelial progenitor cells and burn injury - exploring the relationship. [PDF]

, 2016
Burn wounds result in varying degrees of soft tissue damage that are typically graded clinically. Recently a key participant in neovascularization, the endothelial progenitor cell, has been the subject of intense cardiovascular research to explore ...
Adnani, Blake O, Araniego, Cheryl Ann, Banyard, Derek A, Melkumyan, Satenik, Widgerow, Alan D   +4 more
core   +2 more sources

GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. [PDF]

, 2016
Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous.
David James, C, Engler, Jane R, Ewald, Andrew J, Gong, Henry, Huillard, Emmanuelle, Koshkakaryan, Gayane, Lindberg, Olle R, McKinney, Andrew, Molinaro, Annette M, Phillips, Joanna J, Robinson, Aaron E, Shieh, Joseph T   +11 more
core   +1 more source

Nuclear GSK-3β and Oncogenic KRas Lead to the Retention of Pancreatic Ductal Progenitor Cells Phenotypically Similar to Those Seen in IPMN

Frontiers in Cell and Developmental Biology, 2022
Glycogen synthase kinase-3β (GSK-3β) is a downstream target of oncogenic KRas and can accumulate in the nucleus in pancreatic ductal adenocarcinoma (PDA).
Li Ding, Kaely Roeck, Cheng Zhang, Brooke Zidek, Esther Rodman, Yasmin Hernandez-Barco, Jin-San Zhang, Jin-San Zhang, William Bamlet, Ann Oberg, Lizhi Zhang, Nabeel Bardeesy, Hu Li, Daniel Billadeau   +13 more
doaj   +1 more source

Single-nuclei analysis reveals depot-specific transcriptional heterogeneity and depot-specific cell types in adipose tissue of dairy cows

Frontiers in Cell and Developmental Biology, 2022
Adipose tissue (AT) is an endocrine organ with a central role on whole-body energy metabolism and development of metabolic diseases. Single-cell and single-nuclei RNA sequencing (scRNA-seq and snRNA-seq, respectively) analyses in mice and human AT have ...
Tainara C. Michelotti, Brent R. Kisby, Lauryn S. Flores, Alexandra P. Tegeler, Mohamed Fokar, Chiquito Crasto, Chiquito Crasto, Chiquito Crasto, Bruno C. Menarim, Shavahn C. Loux, Clarissa Strieder-Barboza, Clarissa Strieder-Barboza   +11 more
doaj   +1 more source

Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction - (TOPCARE-AMI) [PDF]

, 2002
Background - Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling.
Aicher, A, Assmus, B, Britten, M, Dimmeler, S, Döbert, N, Grünwald, F, Hoelzer, D, Lehmann, R, Martin, H, Schächinger, V, Teupe, C, Urbich, C, Zeiher, AM   +12 more
core   +1 more source