Results 21 to 30 of about 516,619 (423)
Evaluation of network-guided random forest for disease gene discovery [PDF]
Gene network information is believed to be beneficial for disease module and pathway identification, but has not been explicitly utilized in the standard random forest (RF) algorithm for gene expression data analysis. We investigate the performance of a network-guided RF where the network information is summarized into a sampling probability of ...
arxiv +1 more source
Progesterone significantly enhances the mobility of boar spermatozoa [PDF]
Progesterone released from the cumulus cells of the oocyte causes a number of physiological responses in human sperm cells including hyperactivation, acrosome reaction and chemotaxis. We employed a validated sperm mobility assay, which involves measuring
Adya, Ashok K.+6 more
core +3 more sources
Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis?
In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo-receptive state to allow implantation during the window of receptivity.
R. Marquardt+3 more
semanticscholar +1 more source
Background: Luteal phase deficiency is common in assisted reproductive technology and is characterized by inadequate progesterone production. Various studies have shown that administration of progesterone in fresh embryo transfer cycles increases the ...
Samaneh Jalaliani+4 more
doaj +1 more source
ObjectiveTo investigate the impact of the progesterone concentration on the human chorionic gonadotropin (hCG) trigger day on clinical outcomes with an antagonist protocol.MethodsThe retrospective cohort study included a total of 1,550 fresh autologous ...
Jianing Xu+3 more
doaj +1 more source
Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]
Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Friese, Klaus+6 more
core +1 more source
Progesterone and neuroprotection [PDF]
Numerous studies aimed at identifying the role of estrogen on the brain have used the ovariectomized rodent as the experimental model. And while estrogen intervention in these animals has, at least partially, restored cholinergic, neurotrophin and cognitive deficits seen in the ovariectomized animal, it is worth considering that the removal of the ...
Meharvan Singh, Chang Su
openaire +3 more sources
Steroid hormone bioavailability is controlled by the lymphatic system
The steroid hormone progesterone accounts for immune tolerance in pregnancy. Enhanced progesterone metabolism to 6α-OH-pregnanolone occurs in complicated pregnancies such as in preeclampsia with preterm delivery or intrauterine growth restriction, and in
Rahel Klossner+9 more
doaj +1 more source
N-glycans of human amniotic fluid transferrin stimulate progesterone production in human first trimester trophoblast cells in vitro [PDF]
Aims: During pregnancy, the placenta produces a variety of steroid hormones and proteins. Several of these substances have been shown to exert immunomodulatory effects.
Briese, V.+8 more
core +1 more source
Preterm birth is the primary cause of infant death worldwide. A short cervix in the second trimester of pregnancy is a risk factor for preterm birth. In specific patient cohorts, vaginal progesterone reduces this risk.
L. Kindinger+9 more
semanticscholar +1 more source