Results 161 to 170 of about 4,627,535 (339)
International Journal of Cancer, EarlyView.ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer +2 more
wiley +1 more source
Cardiometabolic Health and Risk of Breast Cancer Subtypes Among US Black Women
International Journal of Cancer, EarlyView.ABSTRACT In the United States (US), cardiometabolic conditions and aggressive breast cancers are both more common among Black women than White women. Using data from 57,453 participants in the Black Women's Health Study (BWHS), we prospectively evaluated associations of body mass index (BMI), Type 2 diabetes, hypertension, and hypercholesterolemia with
Yifei Shan +4 more
wiley +1 more source
The Epithelial Epigenome: A Unified Platform for Cancer Risk Prediction and Prevention Monitoring
International Journal of Cancer, EarlyView.ABSTRACT Intrinsic biological processes and carcinogenic exposures leave cumulative DNA methylation (DNAme) imprints in epithelial cells. These changes reflect cellular composition, replicative/mitotic age and impaired differentiation capacity, and arise long before clinically detectable cancer, consistent with the concept of field cancerisation ...
Martin Widschwendter
wiley +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev +3 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background The choice of tocolytic drugs is one of the most debated aspects of preterm birth management. Objective This network meta‐analysis aimed to establish an evidence‐based hierarchy for tocolytics used in preterm labor by evaluating their efficacy in delaying delivery, safety, and neonatal outcomes.
Barbara Gardella +5 more
wiley +1 more source
Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.
Genes & Development, 1995 J. Lydon +8 more
semanticscholar +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To examine the effect of controlled ovarian stimulation (COS) protocol on follicular synchrony in a subsequent in vitro fertilization (IVF) cycle in patients whose previous cycle was canceled due to asynchrony. Methods A single‐center retrospective‐cohort study (January 2018–March 2024), including women undergoing IVF who had: (1) a ...
Alyssa Hochberg +5 more
wiley +1 more source
The progesterone receptor. Biological effects of progestins and antiprogestins
, 1994 The progesterone receptor displays the typical three-domains structure of the steroid-thyroid receptor family. The central domain contains two 'zinc finger ' structures responsible for the specific recognition of the cognate DNA sequences.
A. Chauchereau +5 more
core
Epilepsy surgery through a reproductive lifespan lens
Epilepsia, EarlyView.
Aisha A. Abdulrazaq +2 more
wiley +1 more source