Results 141 to 150 of about 4,627,535 (339)
Immunolocalization of progesterone receptors in binucleate trophoblast cells of the buffalo placenta (Bubalus bubalis) [PDF]
Biotemas, 2007 The binucleate trophoblast cells (CTBs) of the water buffalo placenta (Bubalus bubalis) were studied with emphasis on the presence of progesterone receptor.
Carlos Eduardo Ambrósio +4 more
doaj
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose To determine whether perimenopausal women receiving menopausal hormone therapy (MHT) have decreased odds of developing soft‐tissue shoulder disorders compared with women without an active MHT prescription, specifically adhesive capsulitis, bursitis, bicipital tendinitis, calcific tendinitis, atraumatic rotator cuff tear/rupture, and shoulder ...
Isha K. Shah +6 more
wiley +1 more source
Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus
Acta Dermato-Venereologica, 2018 Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng +6 more
doaj +1 more source
Global alignment of progesterone-bound steroid receptors.
, 2013 A cartoon representation of the ancSR2–progesterone–mifepristone (slate blue), ancSR2–progesterone (orange, PDB accession code: 4FN9), and progesterone receptor–progesterone (purple, PDB accession code 1A28) complexes overlay with high overall structural
Jennifer K. Colucci (119487) +1 more
core +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Objectives This paper aims to describe the treatment patterns of contemporary systemic menopausal hormone therapy (MHT) in Denmark. Study design This study is a nationwide drug utilization study including an open cohort of all Danish women aged >40 years between 2000–2024.
Hannah K. Wood‐Kurland +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley +1 more source
Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network
Clinical Pharmacology &Therapeutics, EarlyView.Human gestation is characterized by dynamic changes in maternal physiology and maturation of tissue functions before and after birth. The fetus and neonate are highly dependent upon transfer of maternal nutrients via the placenta and lactating mammary gland, which frequently involve selective membrane transporter proteins.
Joanne Wang +16 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pregnancy results in multiple physiological changes that impact drug disposition. For example, hepatic CYP3A activity and renal transporter‐mediated clearance increase in late pregnancy, but the time course of these changes across pregnancy is not known.
Aurora K Authement +3 more
wiley +1 more source
Effect of administration of selective progesterone receptor modulators (SPRMs) on uterine and endometrial morphology [PDF]
, 2018 INTRODUCTION: The human menstrual cycle is regulated by sex-steroid hormones, including oestrogen (E), progesterone (P4) and androgens which act by ligand binding to their cognate receptors. Perturbation of the complex series of events governing the
Whitaker, Lucy Harriet Ravenscroft
core