Results 121 to 130 of about 129,630 (263)

Menopausal hormone therapy and comprehensive postmenopausal care in gynecologic cancer survivors: A position paper from the FIGO Committee on Women at Menopausal Age

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho   +8 more
wiley   +1 more source

Unlocking insights: Validating a comprehensive model for predicting spontaneous preterm delivery and microbial invasion in women facing preterm labor

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Preterm labor is a multifactorial syndrome with diverse etiologies such as infection, inflammation, uteroplacental dysfunction, stress, and immune dysregulation. Identifying women at high risk remains a challenge, and multivariate prediction models have been developed to enhance risk stratification.
Ester del Barco   +12 more
wiley   +1 more source

CRL4<sup>AMBRA1</sup>-mediated progesterone receptor degradation drives progestin resistance and represents a therapeutic vulnerability in endometrial cancer. [PDF]

open access: yesInt J Biol Sci
Sheng Y   +15 more
europepmc   +1 more source

Unfolding the Action of Progesterone Receptors [PDF]

open access: yesJournal of Biological Chemistry, 2003
Xiaotao, Li, Bert W, O'Malley
openaire   +2 more sources

A uterine‐centric view of reproductive senescence: Genetic insights into late‐life performance in laying hens

open access: yesiMetaOmics, EarlyView.
This study identifies uterus weight as a heritable (h2 = 0.45) intermediate phenotype that independently associates with late‐life egg production and eggshell quality in aged laying hens. Genome‐wide association study (GWAS) reveals a genome‐wide significant locus on chromosome 3 and suggestive loci on chromosome 11 for uterus weight, mediation ...
Junnan Zhang   +7 more
wiley   +1 more source

Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9‐mediated R‐loop resolution

open access: yesiMeta, EarlyView.
This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang   +18 more
wiley   +1 more source

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