Estrogen receptor (ER) and progesterone receptor (PgR) in breast cancer of Indian women
Breast Cancer: Targets and Therapy, 2011 Amit V Patil1, Rahul S Bhamre2, Rajeev Singhai3, Mukund B Tayade4, Vinayak W Patil31Department of General Surgery, Government Medical College, Miraj, Maharashtra, India; 2Department of General Surgery, DY Patil Hospital and Research Centre, Nerul, Navi ...
Patil AV +4 more
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Progesterone receptors in the human placenta: Expression, signalling characteristics and functional relevance [PDF]
, 2011 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The human placenta is a transient life sustaining organ which is responsible for mediating all the physiological exchanges between the mother and the fetus.
Zachariades, Elena
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Internalisation of membrane progesterone receptor-α after treatment with progesterone: Potential involvement of a clathrin-dependent pathway [PDF]
, 2010 This article has been made available through the Brunel Open Access Publishing Fund.Internalisation and recycling of seven trans-membrane domain receptors is a critical regulatory event for their signalling.
Reynolds, A +5 more
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Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]
, 2009 Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Ochsenkühn, Robert +6 more
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The Effect of Imbalanced Progesterone Receptor-A/-B Ratio on Gelatinase Expressions in Endometriosis [PDF]
International Journal of Fertility and Sterility, 2019 Background Gelatinases degrade extracellular matrix (ECM) components to allow for physiological remodeling and contribute to pathological tissue destruction in endometriosis.
Sepideh Mousazadeh +4 more
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Estrogen and progesterone receptor expression in breast carcinoma
Journal of Pathology of Nepal, 2011 Background: Breast carcinoma is the most common malignancy diagnosed among women worldwide and second leading cause of cancer mortality. One of the hallmarks of the disease is expression of estrogen receptor and progesterone receptor that ultimately ...
TB Pathak +7 more
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Progesterone receptors, their isoforms and progesterone regulated transcription [PDF]
Molecular and Cellular Endocrinology, 2012 This review discusses mechanisms by which progesterone receptors (PR) regulate transcription. We examine available data in different species and tissues regarding: (1) regulation of PR levels; and (2) expression profiling of progestin-regulated genes by total PRs, or their PRA and PRB isoforms.
Britta M, Jacobsen, Kathryn B, Horwitz
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Progestin receptor-mediated reduction of anxiety-like behavior in male rats. [PDF]
PLoS ONE, 2008 BACKGROUND: It is well known progesterone can have anxiolytic-like effects in animals in a number of different behavioral testing paradigms. Although progesterone is known to influence physiology and behavior by binding to classical intracellular ...
Catherine J Auger, Robin M Forbes-Lorman
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Reproductive functions of the progesterone receptor
Journal of the Society for Gynecologic Investigation, 2000 The steroid hormone progesterone plays a central role in the reproductive events associated with pregnancy establishment and maintenance. Physiological effects of progesterone are mediated by interaction of the hormone with specific intracellular progesterone receptors (PRs) that are expressed as two protein isoforms, PR-A and PR-B. Both proteins arise
Conneely, O.M. +4 more
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Progesterone Regulation of the Progesterone Receptor in Rat Gonadotropes* [PDF]
Endocrinology, 2000 For rat pituitary cells, progesterone receptor (PR) protein localizes to gonadotropes and PR messenger RNA is induced by E2 and rapidly but transiently down-regulated by progesterone. Here we quantitatively establish the down-regulatory effect of progesterone on PR protein and evaluate possible mechanisms.
J L, Turgeon, D W, Waring
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