Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]
, 1993 Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J. +5 more
core +1 more source
Efficacy of Fractional Laser on Steroid Receptors in GSM Patients
Bioengineering, 2023 Background: To compare the efficacy of CO2 fractional laser with that of topical estriol for treating genitourinary syndrome of menopause and to investigate the relationship between epithelial thickness and vaginal atrophy.
Stella Catunda Pinho +9 more
doaj +1 more source
17,β-estradiol inhibits hepatitis C virus mainly by interference with the release phase of its life cycle [PDF]
, 2016 Rationale & Aim: Estrogen and estrogen-mediated signalling protect from hepatitis C virus through incompletely understood mechanisms. We aimed to ascertain which phase(s) of HCV life cycle is/are affected by estrogens.
Barbaglia, Matteo N. +10 more
core +2 more sources
Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]
, 2018 Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng +2 more
core +2 more sources
Placental weight and mortality in premenopausal breast cancer by tumor characteristics [PDF]
, 2012 Placental weight may be regarded as an indirect marker of hormone exposures during pregnancy. There is epidemiological evidence that breast cancer mortality in premenopausal women increases with placental weight in the most recent pregnancy.
Adolfsson, J. +6 more
core +1 more source
Physiological Action of Progesterone in the Nonhuman Primate Oviduct
Cells, 2022 Therapies that target progesterone action hold potential as contraceptives and in managing gynecological disorders. Recent literature reviews describe the role of steroid hormones in regulating the mammalian oviduct and document that estrogen is required
Ov D. Slayden +2 more
doaj +1 more source
Hormone Receptor Status in Breast Cancer and its Relation to Age and Other Prognostic Factors
Breast Cancer: Basic and Clinical Research, 2011 Background Increasing evidence shows the importance of young age, estrogen receptor (ER), progesterone receptor (PR) status, and HER-2 expression in patients with breast cancers.
Ali Pourzand +4 more
doaj +1 more source
Short oestrous cycles in sheep during anoestrus involve defects in progesterone biosynthesis and luteal neovascularisation [PDF]
, 2014 Anoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes the induced ovulation is followed by an abnormally short luteal phase causing a so called, "short cycle".
Acritopoulou +28 more
core +3 more sources
Progesterone receptors, their isoforms and progesterone regulated transcription [PDF]
Molecular and Cellular Endocrinology, 2012 This review discusses mechanisms by which progesterone receptors (PR) regulate transcription. We examine available data in different species and tissues regarding: (1) regulation of PR levels; and (2) expression profiling of progestin-regulated genes by total PRs, or their PRA and PRB isoforms.
Britta M, Jacobsen, Kathryn B, Horwitz
openaire +2 more sources
BMC Evolutionary Biology, 2019 Background Nuclear progesterone receptor (nPR) is an evolutionary innovation in vertebrates that mediates genomic responses to progesterone. Vertebrates also respond to progesterone via membrane progesterone receptors (mPRs) or membrane associated ...
Jianfeng Ren +3 more
doaj +1 more source