Results 31 to 40 of about 220,321 (314)
Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5a-reductase in the dorsal spinal cord of animals with neuropathic pain: effects of progesterone administration [PDF]
, 2016 Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. The presence and biological activity of steroidogenic regulatory proteins and enzymes in the spinal cord suggests that neurosteroids ...
Adler, Natalia Sol +6 more
core +2 more sources
Медична наука України, 2017 Relevance. An important medical and social problem of modern obstetrics is threatening abortion. Among all threatened abortion risk factors today a special attention is given to genetic factors, in particular, to progesterone receptor gene polymorphism ...
O.S. Kryvopustov
doaj +1 more source
The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]
, 2009 More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia +9 more
core +1 more source
Synthetic epoxy-pregnan steroids: effects on anxiety behavior in rats [PDF]
, 2016 Neurosteroids like 3α-OH-5α-pregnan-20-one (allopregnanolone) and 3α-OH-5β-pregnan-20-one (pregnanolone) modulate the γ-aminobutyric acid-A (GABAA) receptor function and produce several effects that can be considered for therapeutical pruposes like ...
Coirini, Hector +2 more
core +1 more source
Indonesian Journal of Obstetrics and GynecologyObjective: Progesterone functions by inhibiting the release of Gonadotropin-Releasing Hormone (GnRH), which decreases Follicle-Stimulating Hormone (FSH) levels and converts them into hypoestrogens.
Suryanti +6 more
doaj +1 more source
Progesterone differentially affects the transcriptomic profiles of cow endometrial cell types
BMC Genomics, 2022 Background The endometrium is a heterogeneous tissue composed of luminal epithelial (LE), glandular epithelial (GE), and stromal cells (ST), experiencing progesterone regulated dynamic changes during the estrous cycle.
Gonçalo Pereira +6 more
doaj +1 more source
Expression of membrane and nuclear progesterone receptors in two human placental choriocarcinoma cell lines (JEG-3 and BeWo): Effects of syncytialization [PDF]
, 2011 This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright @ 2011 Spandidos Publications Ltd.A vital function of the human placenta is to produce steroid hormones such as ...
Foster, H +5 more
core +1 more source
Scientific Reports, 2017 Progesterone can block the oestradiol-induced GnRH/LH surge and inhibit LH pulse frequency. Recent studies reported that progesterone prevented premature LH surges during ovarian hyperstimulation in women. As the most potent stimulator of GnRH/LH release,
Wen He +8 more
doaj +1 more source
Hormonal modulators of glial ABCA1 and apoE levels[S]
Journal of Lipid Research, 2013 Apolipoprotein E (apoE) is the major lipid carrier in the central nervous system. As apoE plays a major role in the pathogenesis of Alzheimer disease (AD) and also mediates repair pathways after several forms of acute brain injury, modulating the ...
Jianjia Fan +9 more
doaj +1 more source
Cancer Reports, 2022 Background Hormone Receptor (HR)‐discordance between primary breast cancer and metastasis is a known biological phenomenon. Discordance studies usually comprise a heterogeneous group of HR‐positive and negative patients and allow for the comparison of ...
Sirus Djahansouzi +4 more
doaj +1 more source