Results 51 to 60 of about 4,627,535 (339)

Rapid progesterone actions on thymulin-secreting epithelial cells cultured from rat thymus [PDF]

, 1999
Many soluble factors of neural, endocrine, paracrine and autocrine origin are present in the thymus and modulate its function. Long-term effects of sex steroids have! been documented for thymocytes and cells of the thymic microenvironment. In this report
Downing, James E. G., Brucker, Cosima, Mentlein, Rolf, Kendall, Marion D., Head, Gail M.   +4 more
core   +1 more source

Hormone Receptor Status in Breast Cancer and its Relation to Age and Other Prognostic Factors

Breast Cancer: Basic and Clinical Research, 2011
Background Increasing evidence shows the importance of young age, estrogen receptor (ER), progesterone receptor (PR) status, and HER-2 expression in patients with breast cancers.
Ali Pourzand, M. Bassir A. Fakhree, Shahryar Hashemzadeh, Monireh Halimi, Amir Daryani   +4 more
doaj   +1 more source

Physiological Action of Progesterone in the Nonhuman Primate Oviduct

Cells, 2022
Therapies that target progesterone action hold potential as contraceptives and in managing gynecological disorders. Recent literature reviews describe the role of steroid hormones in regulating the mammalian oviduct and document that estrogen is required
Ov D. Slayden, Fangzhou Luo, Cecily V. Bishop   +2 more
doaj   +1 more source

The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium [PDF]

, 2008
Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation.
Cartwright, JE, Yliheikkila, M., Marius C. Jones, Lam, Eric W.-F., Eric W.-F. Lam, Matti Poutanen, Fusi, L, Luca Fusi, Kim, J. J., Ho, K.-K., Teklenburg, G., Kim, JJ, Poutanen, M, Trew, G, Lavery, S., Cartwright, J. E., Judith E. Cartwright, Cloke, B, Kajihara, T, Geoffrey Trew, Takeshi Kajihara, Huhtinen, K., Jones, M. C., Stuart Lavery, Lam, EW, Jan J. Brosens, Huhtinen, K, Lavery, S, J. Julie Kim, Trew, G., Poutanen, M., Kaisa Huhtinen, Kajihara, T., Brosens, Jan J., Cloke, B., Ho, KK, Teklenburg, G, Jones, MC, Brosens, JJ, Yliheikkilä, M, Maria Yliheikkilä, Gijs Teklenburg, Brianna Cloke, Ka-Kei Ho, Fusi, L.   +44 more
core   +1 more source

Selective progesterone receptor modulators (SPRMs): progesterone receptor action, mode of action on the endometrium and treatment options in gynecological therapies

Expert opinion on therapeutic targets, 2016
Introduction: The progesterone receptor plays an essential role in uterine physiology and reproduction. Selective progesterone receptor modulators (SPRMs) have emerged as a valuable treatment option for hormone dependent conditions like uterine fibroids,
A. Wagenfeld, P. Saunders, L. Whitaker, H. Critchley   +3 more
semanticscholar   +1 more source

Effects of the selective progesterone receptor modulator asoprisnil on uterine artery blood flow, ovarian activity, and clinical symptoms in patients with uterine leiomyomata scheduled for hysterectomy [PDF]

, 2008
Introduction: Asoprisnil, a novel orally active selective progesterone receptor modulator, is being studied for the management of symptomatic uterine leiomyomata. The exact mechanism of action is not yet discerned.
Williams, A.R.W., Chwalisz, K., Hapangama, D., Critchley, Hilary O.D., Wilkens, Julia, Walker, Jane, Lawrence, A.C., Williams, Alistair R.W., Lumsden, M.A., Lawrence, Alexandra C., Ingamells, S., Chwalisz, Kristof, Hapangama, Dharani, Critchley, H.O.D., Han, Cong, Ingamells, Susan, Wilkens, J., Cameron, I.T., Cameron, Iain T., Lumsden, Mary Ann, Han, C., Walker, J.   +21 more
core   +1 more source

Genomic sequence analyses of classical and non-classical lamprey progesterone receptor genes and the inference of homologous gene evolution in metazoans

BMC Evolutionary Biology, 2019
Background Nuclear progesterone receptor (nPR) is an evolutionary innovation in vertebrates that mediates genomic responses to progesterone. Vertebrates also respond to progesterone via membrane progesterone receptors (mPRs) or membrane associated ...
Jianfeng Ren, Yu-Wen Chung-Davidson, Liang Jia, Weiming Li   +3 more
doaj   +1 more source

Estrogen and Progesterone Receptors in the Endometrium

Annals of the New York Academy of Sciences, 1997
The endometrium, as a target of estrogens and progestins, possesses the respective receptor proteins. These receptors belong to the superfamily of nuclear receptors, having important functional domains required for steroid ligand binding, for dimer formation, for interaction with HREs of DNA, for transcription modulation, for association with other ...
Moutsatsou, P., Sekeris, C.E.
openaire   +4 more sources

3D models of lamprey corticoid receptor complexed with 11-deoxycortisol and deoxycorticosterone [PDF]

, 2011
The serum of Atlantic sea lamprey, a basal vertebrate, contains two corticosteroids, 11-deoxycortisol and deoxycorticosterone. Only 11-deoxycortisol has high affinity [Kd~3 nM] for the corticoid receptor [CR] in lamprey gill cytosol. To investigate the
Paiyuam Asnaashari, Michael E. Baker, Kayla Y. Uh   +2 more
core   +1 more source

RISK FACTORS STUDY OF THREATENED ABORTION OCCURRING IN WOMEN WITH REGARD TO PROGESTERONE RECEPTOR GENE POLYMORPHISM

Медична наука України, 2017
Relevance. An important medical and social problem of modern obstetrics is threatening abortion. Among all threatened abortion risk factors today a special attention is given to genetic factors, in particular, to progesterone receptor gene polymorphism ...
O.S. Kryvopustov
doaj   +1 more source