Results 71 to 80 of about 1,285,180 (252)

Long‐term prognosis is associated with residual disease after neoadjuvant systemic therapy but not with initial nodal status

BJS (British Journal of Surgery), EarlyView., 2020
This long‐term follow‐up study determined survival rates in a Swedish national cohort of 417 patients with breast cancer who all had neoadjuvant systemic therapy (NAST). Sentinel lymph node biopsy (SLNB) was performed before NAST in clinically node‐negative and after NAST in clinically node‐positive patients.
L. Zetterlund, F. Celebioglu, T. Hatschek, J. Frisell, J. de Boniface   +4 more
wiley   +1 more source

Estrogen and Progesterone Receptor Expression and its Correlation with Various Clinicopathological Parameters in Ovarian Tumors

Middle East Journal of Cancer, 2014
Background: This study evaluates estrogen and progesterone expressions in patients with ovarian tumors (both benign and malignant) and their correlation with various clinicopathological prognostic parameters.
Shilpa Garg, Nisha Marwah, Gulshan Chauhan, Sumiti Gupta, Rajiv Goyal, Pushpa Dahiya, Promil Jain, Rajiv Sen   +7 more
doaj  

Exploring the Genetic Background of the Differences in Nest-Building Behavior in European Rabbit

Animals, 2020
Once a day, nursing and absentee mothering make the wild rabbit (Oryctolagus cuniculus) an ideal model animal for measuring differences in maternal behavior.
Ildikó Benedek, Vilmos Altbӓcker, Attila Zsolnai, Tamás Molnár   +3 more
doaj   +1 more source

Biopsy confirmation of metastatic sites in breast cancer patients:clinical impact and future perspectives [PDF]

, 2014
Determination of hormone receptor (estrogen receptor and progesterone receptor) and human epidermal growth factor receptor 2 status in the primary tumor is clinically relevant to define breast cancer subtypes, clinical outcome, and the choice of therapy.
Carmen Criscitiello, Thompson, Alastair M., Locatelli, Marzia, Curigliano, Giuseppe, Orsi, Franco, F. Orsi, Fabrice André, Criscitiello, Carmen, Minchella, Ida, M. Locatelli, F. André, Thompson, Alastair M, Marzia Locatelli, Giuseppe Curigliano, Curigliano, Guiseppe, Ida Minchella, De Laurentiis, Michele, Lucia Gelao, Luca Fumagalli, Franco Orsi, Esposito, Angela, Goldhirsch, Aron, Angela Esposito, A. M. Thompson, DE LAURENTIIS, MICHELINO, L. Fumagalli, A. Goldhirsch, André, Fabrice, Michele De Laurentiis, Alastair M Thompson, A. Esposito, Fumagalli, Luca, G. Curigliano, M. De Laurentiis, Aron Goldhirsch, C. Criscitiello, L. Gelao, Gelao, Lucia, I. Minchella   +38 more
core   +2 more sources

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

Effect of administration of selective progesterone receptor modulators (SPRMs) on uterine and endometrial morphology [PDF]

, 2018
INTRODUCTION: The human menstrual cycle is regulated by sex-steroid hormones, including oestrogen (E), progesterone (P4) and androgens which act by ligand binding to their cognate receptors. Perturbation of the complex series of events governing the
Whitaker, Lucy Harriet Ravenscroft
core   +3 more sources

Estrogen and progesterone receptor testing in breast carcinoma: concordance of results between local and reference laboratories in Brazil

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Breast cancer accounts for approximately one quarter of all cancers in females. Estrogen and progesterone receptor testing has become an essential part of the clinical evaluation of breast carcinoma patients, and accurate results ...
Sheila Cristina Lordelo Wludarski, Lisandro Ferreira Lopes, Ívison Xavier Duarte, Filomena Marino Carvalho, Lawrence Weiss, Carlos Eduardo Bacchi   +5 more
doaj   +1 more source

Data on RT-qPCR assay of nuclear progesterone receptors (nPR), membrane progesterone receptors (mPR) and progesterone receptor membrane components (PGRMC) from human uterine endometrial tissue and cancer cells of the Uterine Cervix

Data in Brief, 2020
A previous investigation showed that the endometrium normalized in women with endometrial hyperplasia after three months treatment with high dose levonorgestrel IUS (intrauterine system) [1]. The effect was maintained even if immunohistochemical analyses
Natalia Smaglyukova, Elise Thoresen Sletten, Anne Ørbo, Georg Sager   +3 more
doaj   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Estrogen Receptor Positive/Progesterone Receptor Negative Breast Carcinomas: A Subgroup Deserves Particular Interest

Bezmiâlem Science, 2015
Objective:Breast carcinomas positive for the estrogen receptor (ER+) but negative for the progesterone receptor (PR−) have unfavorable prognostic features and are resistant to tamoxifen therapy. The goal of this study was to highlight the significance of
Zühal GÜCİN, Melin Özgün GEÇER, Nur BÜYÜKPINARBAŞILI, Cavide SÖNMEZ, Yeliz Emine ERSOY, Mahmut MÜSLÜMANOĞLU   +5 more
doaj   +1 more source