Results 201 to 210 of about 219,338 (264)
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Gynecologic Oncology, 1974
Abstract Coordinated estrogen- and progesterone-induced changes regulate biological functions of the endometrium. The uterine deciduoma reaction is used as a model in defining the mechanism of the progesterone-induced endometrial transformations. Uterine progesterone concentrations were determined by radioimmunoassay during three critical periods ...
Walter G. Wiest, B. Ramanath Rao
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Abstract Coordinated estrogen- and progesterone-induced changes regulate biological functions of the endometrium. The uterine deciduoma reaction is used as a model in defining the mechanism of the progesterone-induced endometrial transformations. Uterine progesterone concentrations were determined by radioimmunoassay during three critical periods ...
Walter G. Wiest, B. Ramanath Rao
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Progesterone and progesterone receptors in reptiles
General and Comparative Endocrinology, 2002The role of progesterone (P) has been most extensively studied in the female reproductive tissues (ovary, reproductive tract, mammary gland) and in the brain, in which it is an important regulator and modulator in conjunction with estradiol (E). In nonmammalian vertebrate species, less work has been done on P metabolites involved in ovulation.
Ian P. Callard, Noemı́ Custodia-Lora
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Progesterone receptor coactivators
Steroids, 2000Progesterone action is mediated by intracellular progesterone receptors that regulate target gene transcription. Recently, numerous proteins termed coactivators have been identified that are recruited by the liganded progesterone receptor and enhance receptor-dependent transactivation.
Brian G. Rowan, Bert W. O'Malley
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Novel Mechanisms of Progesterone Antagonists and Progesterone Receptor
Journal of the Society for Gynecologic Investigation, 2000The progesterone receptor (PR), as a member of the nuclear receptor superfamily of ligand-dependent transcription factors, activates gene transcription through binding to specific palindromic progesterone response elements (PRE) in the promoter region of progestin-responsive genes.
Susan A. Leonhardt +2 more
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Phosphorylation and Progesterone Receptor Function
The Journal of Steroid Biochemistry and Molecular Biology, 1994Four phosphorylation sites have been identified in the chicken progesterone receptor. Two of these sites exhibit basal phosphorylation which is enhanced upon treatment with hormone and two of the sites are phosphorylated in response to hormone. Mutation of one of these hormone dependent sites, Ser530 to Ala530, causes a decrease in transcriptional ...
N. L. Weigel +5 more
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Progesterone receptor and the mechanism of action of progesterone antagonists
The Journal of Steroid Biochemistry and Molecular Biology, 1995Currently available progesterone antagonists have been suggested to fall into two categories based on differences in how they interact with and inactivate the progesterone receptor (PR). The anti-progestin ZK98299 (Type I) impairs PR association with DNA, while Type II compounds (RU486, ZK112993, ZK98734) promote PR binding to DNA.
Angelo M. DeMarzo +5 more
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Estrogen and progesterone receptors in meningiomas
Surgical Neurology, 1986Estradiol and progesterone receptors were studied in 14 patients with meningiomas. Estrogen receptors were detected by specific monoclonal antibodies, whereas progesterone receptors were assayed by the dextran-coated charcoal method. In 9 cases the estrogen receptors were also investigated in cultured tumor cells.
MAIURI, FRANCESCO +2 more
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