Results 221 to 230 of about 4,627,535 (339)

Prevention of Early Onset of Breast Cancer With Ashwagandha

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm, Su‐Hyeong Kim, Shivendra V. Singh   +2 more
wiley   +1 more source

Arcuate nucleus-specific progesterone receptor knockdown in female mice is sufficient to induce PCOS-like hyperactivity in the reproductive axis. [PDF]

J Neuroendocrinol
Glendining KA, Prescott M, Potapov K, Kip E, Campbell RE.   +4 more
europepmc   +1 more source

COVID‐19 Amplifies Sex‐Specific Dopamine and Glial Responses in a Parkinson's Disease Mouse Model

Movement Disorders, EarlyView.
Abstract Background Exposure to environmental agents, including viral infections, may increase Parkinson's disease (PD) susceptibility, especially in males, but the neurodegenerative risk extent of COVID‐19 remains uncertain. Objectives We investigated the plausible link between severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection and
Ifeoluwa Awogbindin, Mélanie Bourque, Marc Morissette, Marie‐Ève Hamelin, Chantal Rhéaume, Jared VanderZwaag, Antonia Landwehr, Disha Patel, Guy Boivin, Marie‐Ève Tremblay, Thérèse Di Paolo   +10 more
wiley   +1 more source

CRL4^AMBRA1-mediated progesterone receptor degradation drives progestin resistance and represents a therapeutic vulnerability in endometrial cancer. [PDF]

Int J Biol Sci
Sheng Y, Ni T, Ding X, Huang J, Zhao X, Li X, Li Q, Wang J, Yang X, Zhang L, Zheng X, Cao D, Su R, Lu X, Hou J, Wang Y.   +15 more
europepmc   +1 more source

Prognostic value of estrogen receptor α and progesterone receptor conversion in distant breast cancer metastases

Cancer, 2012
L. Hoefnagel, C. Moelans, S. Meijer, H. van Slooten, P. Wesseling, J. Wesseling, P. Westenend, J. Bart, C. Seldenrijk, I. Nagtegaal, J. Oudejans, P. van der Valk, C. V. van Gils, E. van der Wall, P. V. van Diest   +14 more
semanticscholar   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Digital Quantification of Progesterone Receptor Expression in Meningiomas: Associations with WHO Grade and Clinicopathological Features. [PDF]

Turk Patoloji Derg
Akca Y, Gökçe EB.
europepmc   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Somatosensory cortical progesterone receptor signaling regulates the episodic to chronic migraine transformation. [PDF]

Neurobiol Dis
Joshi S, Williamson J, Etcheberrigaray D, Goodkin HP, Kapur J.   +4 more
europepmc   +1 more source

Breast Skin Lesions in a 79‐Year‐Old Woman

JEADV Clinical Practice, EarlyView.
Javier Lorenz‐Dolz, Fátima Mayo‐Martínez, Andrea Díez Santandreu, Onofre Sanmartín Jiménez, Ruggero Moro   +4 more
wiley   +1 more source