Results 241 to 250 of about 2,512,088 (315)

Rosuvastatin Upregulates RCOR1 to Repress C10ORF10 Transcription and Alleviate Oxidative Stress and Plaque Formation in Atherosclerosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rosuvastatin (RVS) is an HMG‐CoA reductase inhibitor with lipid‐lowering properties. This study aims to investigate the role of RVS in plaque formation in atherosclerosis (AS) and its functional mechanism. ApoE−/− mice were fed a high‐fat diet to generate a mouse model of AS.
Xin Fu, Chuang Liu, Ya‐Li Chen, Jie‐Lin Qin, Ting‐Ting Wang, Shan‐Shan Fu   +5 more
wiley   +1 more source

Identification of Novel Progesterone Receptor (PR) Inhibitors (Homo sapiens) from Metabolites of Biotransformation Fungal: A Bioinformatics Approach. [PDF]

Pharmaceuticals (Basel)
Dourado JAE, Lopes SQ, Jimenez DEQ, Ramos RS, Ferreira IM.   +4 more
europepmc   +1 more source

miR‐127‐3p Inhibits Cell Stemness and Docetaxel Resistance in Triple‐Negative Breast Cancer by Targeting KIF3B

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the mechanism of miR‐127‐3p in tumor cell stemness and docetaxel (DTX) resistance in triple‐negative breast cancer (TNBC). hsa‐miR‐127‐3p and KIF3B levels were predicted using databases and validated in TNBC and paracancerous tissues.
Zi‐Chao He, Jun‐Jie Zhao, Ting Yan
wiley   +1 more source

The Impact of Estrogen on Stromal Elements in the Proximal Airway in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
ABSTRACT Objectives Idiopathic subglottic stenosis (iSGS) is an unexplained fibrosis of the proximal airway that predominantly impacts Caucasian women. Clinically, premenopausal patients suffer from higher recurrence rates, potentially implicating ovarian hormone 17B‐estradiol (E2) in disease pathogenesis.
Emily L. Mace, Evan Clark, Edward Talatala, Maxim Litvak, Matthew A. Buendia, Yash A. Choksi, Hongmei Wu, Yueli Zhang, Alexander Hillel, Sam Collins, Quanhu Sheng, Jing Yang, Jason Park, Alexander Gelbard   +13 more
wiley   +1 more source

Prognostic Impact of Estrogen and Progesterone Receptor Expression across Histological Subtypes and Clinical Factors in Epithelial Ovarian Cancer.

Gynecol Obstet Invest
Gasimli K, Wilke AM, Schmeil I, Gasimli B, Karn T, Becker S, Arsenic R, El-Balat A.   +7 more
europepmc   +1 more source

Progesterone receptor is constitutively expressed in induced Pluripotent Stem Cells (iPSCs). [PDF]

Stem Cell Rev Rep
Manganelli M, Mazzoldi EL, Ferraro RM, Pinelli M, Parigi M, Aghel SAM, Bugatti M, Collo G, Stocco G, Vermi W, Masneri S, Almici C, Mori L, Giliani S.   +13 more
europepmc   +1 more source

US incidence of breast cancer subtypes defined by joint hormone receptor and HER2 status.

Journal of the National Cancer Institute, 2014
N. Howlader, S. Altekruse, Christopher I. Li, V. Chen, C. Clarke, L. Ries, K. Cronin   +6 more
semanticscholar   +1 more source

Alginate Therapy for Gastroesophageal Reflux in Pregnancy: A Scoping Review

The Laryngoscope, EarlyView.
ABSTRACT Objective Alginate therapies are a promising option for managing gastroesophageal reflux (GERD), but most treatments are not recommended during pregnancy. This scoping review aimed to summarize the current outcomes research on the use of alginate therapy for treating GERD during pregnancy.
Maya Senthilkumaran, Kaitlyn Hui, Corey Li, Sophia Werden‐Abrams, Phillip Staibano, Benjamin van der Woerd   +5 more
wiley   +1 more source

Body mass index and progesterone receptor in postmenopausal ER-positive/HER2-negative breast cancer: A nation-wide study in Korean breast cancer society and the multi-institutional cohort. [PDF]

Breast
Lee J, Bae SJ, Kim HK, Nam SJ, Kim HJ, Bae SY, Park HY, Ko BK, Park JH, Kwon Y, Park Y, Baek SH, Kook Y, Kim S, Lim YA, Kang HJ, Kim D, Jeong J, Ahn SG.   +18 more
europepmc   +1 more source

Transoral Robotic Lingual Tonsillectomy for Pediatric Obstructive Sleep Apnea

The Laryngoscope, EarlyView.
ABSTRACT Objectives Our objective was to investigate the safety and efficacy of transoral robotic surgery (TORS) lingual tonsillectomy (LT) with and without epiglottopexy and to compare it with non‐robotic approaches for children with obstructive sleep apnea (OSA).
Daniel J. Campbell, Daron Excel, W. Jack Palmer, Heather C. Nardone, Douglas R. Johnston   +4 more
wiley   +1 more source