Results 261 to 270 of about 4,627,535 (339)

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Assessing progesterone receptor modulation in glioblastoma: from <i>in vitro</i> and animal model to a human pilot protocol. [PDF]

Cancer Biol Ther
Arcos-Montoya D, García-López P, Wegman-Ostrosky T, Camacho-Arroyo I, Valdés-Rives SA, Bello-Alvarez C, Manjarrez-Marmolejo J, De La Fuente-Granada M, Ordaz-Ramos A, Ávila-González D, Díaz NF, Guadarrama-Rangel CF, Navarrete AMB, Aboud O, Cantú-de-León DF, Cacho-Díaz B, González-Arenas A.   +16 more
europepmc   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Progesterone receptor B over progesterone receptor A prevents recurrence in bilateral endometriomas. [PDF]

Rev Assoc Med Bras (1992)
Aslan O, Yildiz S, Kaya C, Altinay S, Aydiner IE, Karabulut E, Ekin M, Yasar L.   +7 more
europepmc   +1 more source

High Versus Low Transvaginal Cerclage and Pregnancy Outcomes: A Secondary Analysis of the C‐STICH Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare pregnancy outcomes following high versus low vaginal cerclage in women at high risk of preterm birth. Design Secondary analysis of a multi‐centre randomised control trial. Setting Obstetric units across the UK. Sample Women participating in the C‐STICH trial who received a transvaginal cerclage. Methods Cerclage height was
Laura van der Krogt, Nicole Pilarski, Victoria Hodgetts Morton, Alexandra Emms, Philip Toozs‐Hobson, Lee Middleton, Andrew Shennan, Catherine A. Moakes   +7 more
wiley   +1 more source

Proteomics analysis reveals progesterone receptor induced mitochondria-mediated apoptosis in breast cancer cells. [PDF]

Sci Rep
Woo QY, Lau PK, Lee BTK, Bajalovic N, Lee SH, Leong KS, Pow KY, Hanan S, Meng W, Lai SK, Lin VC.   +10 more
europepmc   +1 more source

Low‐Dose Aspirin in the Prevention of Recurrent Spontaneous Preterm Birth Stratified by Placental Maternal Vascular Malperfusion: Secondary Analysis of a Randomized Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the effectiveness of low‐dose aspirin in the prevention of recurrent preterm birth (PTB) in women with signs of maternal vascular malperfusion (MVM) in the placenta of the previous spontaneous PTB. Design Secondary analysis of the APRIL study.
James A. L. Meliëzer, Anadeijda J. E. M. C. Landman, Adelia A. Gieskes, Marianna Bugiani, Laura Visser, Mireille N. Bekker, Judith O. E. H. van Laar, Marieke Sueters, Sanne J. Gordijn, Joris van Drongelen, J. Marko Sikkema, Wietske Hermes, Anjoke J. M. Huisjes, Dimitri N. M. Papatsonis, Janine Boon, Joost J. Zwart, Christianne J. M. de Groot, Martijn A. Oudijk, Marjon A. de Boer   +18 more
wiley   +1 more source

Independent Relevance of Estrogen Receptor and Progesterone Receptor Statuses in DCIS on Risk of Subsequent Ipsilateral and Contralateral Invasive Breast Events in Absence of Endocrine Therapy. [PDF]

Cancers (Basel)
O'Keefe TJ, Guo A, Vera DR, Wallace AM.
europepmc   +1 more source

Periconceptual Progesterone Use and Hypertensive Disorders of Pregnancy: A Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate whether periconceptual use of progesterone is associated with an altered risk of new‐onset hypertensive disorders of pregnancy (gestational hypertension, preeclampsia, or superimposed preeclampsia). Design Population‐based cohort study using statewide pregnancy and birth data from Victoria, Australia, linked with ...
Jessica A. Atkinson, Richard J. Hiscock, Anna Forsythe, Hannah G. Gordon, Jenny Myers, Susan P. Walker, Beverley J. Vollenhoven, Stephen Tong, Roxanne M. Hastie, Anthea C. Lindquist   +9 more
wiley   +1 more source

Replacing BPA: Structural Substitutes BPAF Binding to the Progesterone Receptor Elevates Breast Cancer Risk. [PDF]

Adv Sci (Weinh)
Ji X, Li P, Wu H, Shen L, Wu X, Jiang P, Li Y, Zhang X, Yue H.   +8 more
europepmc   +1 more source