Results 271 to 280 of about 157,138 (359)

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

open access: yesPrecision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang   +7 more
wiley   +1 more source

Maf1 cooperates with progesterone receptor to repress RNA polymerase III transcription of select tRNAs. [PDF]

open access: yesNucleic Acids Res
Finlay-Schultz J   +8 more
europepmc   +1 more source

Ancient and modern mechanisms compete in progesterone receptor activation

open access: gold
Sabab Hasan Khan   +10 more
openalex   +2 more sources

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola   +9 more
wiley   +1 more source

Novel biosensor for high-throughput detection of progesterone receptor-interacting endocrine disruptors [PDF]

open access: gold
Diana A. Stavreva   +5 more
openalex   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Structural proteomics defines a sequential priming mechanism for the progesterone receptor. [PDF]

open access: yesNat Commun
Mann MD   +11 more
europepmc   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan   +2 more
wiley   +1 more source

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