Efficacy of Fractional Laser on Steroid Receptors in GSM Patients
Background: To compare the efficacy of CO2 fractional laser with that of topical estriol for treating genitourinary syndrome of menopause and to investigate the relationship between epithelial thickness and vaginal atrophy.
Stella Catunda Pinho+9 more
doaj +1 more source
Differential effects of steroids and retinoids on bovine myelopoiesis in vitro [PDF]
Pregnancy and parturition are associated with physiological changes caused by steroid hormones. Alterations in number, maturity, and function of polymorphonuclear leukocytes observed in dairy cows at parturition suggest a common causative relationship ...
Burvenich, Christian+3 more
core +1 more source
Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y+79 more
core +1 more source
Physiological Action of Progesterone in the Nonhuman Primate Oviduct
Therapies that target progesterone action hold potential as contraceptives and in managing gynecological disorders. Recent literature reviews describe the role of steroid hormones in regulating the mammalian oviduct and document that estrogen is required
Ov D. Slayden+2 more
doaj +1 more source
Short oestrous cycles in sheep during anoestrus involve defects in progesterone biosynthesis and luteal neovascularisation [PDF]
Anoestrous ewes can be induced to ovulate by the socio-sexual, 'ram effect'. However, in some ewes the induced ovulation is followed by an abnormally short luteal phase causing a so called, "short cycle".
Acritopoulou+28 more
core +3 more sources
Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]
Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J.+5 more
core +1 more source
Hormone Receptor Status in Breast Cancer and its Relation to Age and Other Prognostic Factors
Background Increasing evidence shows the importance of young age, estrogen receptor (ER), progesterone receptor (PR) status, and HER-2 expression in patients with breast cancers.
Ali Pourzand+4 more
doaj +1 more source
Background Nuclear progesterone receptor (nPR) is an evolutionary innovation in vertebrates that mediates genomic responses to progesterone. Vertebrates also respond to progesterone via membrane progesterone receptors (mPRs) or membrane associated ...
Jianfeng Ren+3 more
doaj +1 more source
Progesterone receptor modulators for endometriosis [PDF]
Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. This condition is oestrogen-dependent and thus is seen primarily during the reproductive years. Owing to their antiproliferative effects in the endometrium, progesterone receptor modulators (PRMs) have been advocated for treatment of ...
Huili Zhu+6 more
openaire +3 more sources
Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5a-reductase in the dorsal spinal cord of animals with neuropathic pain: effects of progesterone administration [PDF]
Neuropathic pain is a frequent complication of spinal cord injury (SCI), still refractory to conventional treatment. The presence and biological activity of steroidogenic regulatory proteins and enzymes in the spinal cord suggests that neurosteroids ...
Adler, Natalia Sol+6 more
core +2 more sources