Results 21 to 30 of about 2,591,762 (410)

Intraocular Metastases Secondary to Breast Carcinoma Correlates With Upregulation of Estrogen and Progesterone Receptor Expression in the Primary Tumor [PDF]

, 2016
To compare estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) receptor expression in the primary tumor of patients affected by choroidal metastases from breast carcinoma (BC) versus those with extraocular ...
Frizziero, Luisa, Midena, Edoardo, Miglionico, Giacomo, Parrozzani, Raffaele, Perrini, Pierdavide, Pilotto, Elisabetta, Pulze, Serena, Testi, Ilaria   +7 more
core   +1 more source

Estrogen and progesterone receptor expression in breast carcinoma

Journal of Pathology of Nepal, 2011
Background: Breast carcinoma is the most common malignancy diagnosed among women worldwide and second leading cause of cancer mortality. One of the hallmarks of the disease is expression of estrogen receptor and progesterone receptor that ultimately ...
TB Pathak, R Bashyal, CB Pun, S Shrestha, S Bastola, S Neupane, BR Poudel, MC Lee   +7 more
doaj   +1 more source

The progestin receptor interactome in the female mouse hypothalamus: Interactions with synaptic proteins are isoform specific and ligand dependent [PDF]

, 2017
Progestins bind to the progestin receptor (PR) isoforms, PR-A and PR-B, in brain to influence development, female reproduction, anxiety, and stress. Hormone-activated PRs associate with multiple proteins to form functional complexes. In the present study,
Acharya, Kalpana D, Denner, Larry, Edwards, Dean P, Harling, Moriah, Huang, Shixia, Im, Dana D, Lichti, Cheryl F, Nettles, Sabin A, Pattanayak, Cassandra, Sellers, Katherine J, Srivastava, Deepak P, Tetel, Marc J, Vardar-Ulu, Didem   +12 more
core   +3 more sources

Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]

, 2020
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna, Chen, Joseph C, Giudice, Linda C, Greenblatt, Ruth M, Houshdaran, Sahar, Irwin, Juan C, Smith-McCune, Karen, Vallvé-Juanico, Júlia, Vo, Kim Chi   +8 more
core   +2 more sources

Pathological implication of progesterone receptor expression in patients diagnosed with meningioma [PDF]

Romanian Journal of Neurology
Objectives. To assess the progesterone receptor expression in meningioma patients and to characterize the histopathological and demographic features of them. Materials and methods.
Murooj Jassim Mohammed, Hadeel Ismail Mohsin, Hind Suhail Ali, Asaad F. Albayati   +3 more
doaj   +1 more source

Progestin receptor-mediated reduction of anxiety-like behavior in male rats. [PDF]

PLoS ONE, 2008
BACKGROUND: It is well known progesterone can have anxiolytic-like effects in animals in a number of different behavioral testing paradigms. Although progesterone is known to influence physiology and behavior by binding to classical intracellular ...
Catherine J Auger, Robin M Forbes-Lorman
doaj   +1 more source

Fluorescent ligand for human progesterone receptor imaging in live cells. [PDF]

, 2013
We employed molecular modeling to design and then synthesize fluorescent ligands for the human progesterone receptor. Boron dipyrromethene (BODIPY) or tetramethylrhodamine were conjugated to the progesterone receptor antagonist RU486 (Mifepristone ...
Baker, Michael E, Ellies, Lesley G, Friedman, Beth, Kanter, Joan, Tsien, Roger Y, Weinstain, Roy   +5 more
core   +1 more source

Progesterone receptors, their isoforms and progesterone regulated transcription [PDF]

Molecular and Cellular Endocrinology, 2012
This review discusses mechanisms by which progesterone receptors (PR) regulate transcription. We examine available data in different species and tissues regarding: (1) regulation of PR levels; and (2) expression profiling of progestin-regulated genes by total PRs, or their PRA and PRB isoforms.
Kathryn B. Horwitz, Britta M. Jacobsen
openaire   +2 more sources

Effects of Progesterone and Its Antagonist Mifepristone on Progesterone Receptor A Expression in Human Umbilical Vein Endothelial Cells [PDF]

, 2009
Effects of female steroid hormones on endothelial cells are gaining increased importance due to several studies on the effects of hormonal treatment on cardiovascular risk.
Friese, Klaus, Jeschke, Udo, Kuhn, Christina, Ochsenkühn, Robert, Scholz, Christoph, Schulze, Sandra, Toth, Bettina   +6 more
core   +1 more source

Progesterone Regulation of the Progesterone Receptor in Rat Gonadotropes* [PDF]

Endocrinology, 2000
For rat pituitary cells, progesterone receptor (PR) protein localizes to gonadotropes and PR messenger RNA is induced by E2 and rapidly but transiently down-regulated by progesterone. Here we quantitatively establish the down-regulatory effect of progesterone on PR protein and evaluate possible mechanisms.
Judith L Turgeon, D. W. Waring
openaire   +3 more sources