Results 301 to 310 of about 157,138 (359)

The roles of AKT isoforms in decidualization and embryo implantation using a Progesterone Receptor-Cre mouse model†. [PDF]

Biol Reprod
Adam P, Fabi F, Parent S, Renaud LI, Cadrin M, Asselin E.   +5 more
europepmc   +1 more source

Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive breast cancer: the window-of-opportunity, randomized, phase 2b, PIONEER trial. [PDF]

Nat Cancer
Burrell RA, Kumar S, Provenzano E, Pike C, Dayimu A, McIntosh SA, Pitsinis V, King P, Elsberger B, Govindarajulu S, Satherley L, Hadad S, Schmid P, Agrawal A, Akpuluma B, Bell S, Benson JR, Caldas C, Cheeseman D, Chernukhin I, Forouhi P, Gulsen T, Kleidi E, Pinilla K, Qian W, Abraham JE, Carroll JS, Baird RD.   +27 more
europepmc   +1 more source

Loss of progesterone receptor in smooth muscle cells has no impact on oviductal contractions and preimplantation embryo development†. [PDF]

Biol Reprod
McGlade EA, Mao J, Stephens KK, Rose CN, Lydon JP, Winuthayanon W.   +5 more
europepmc   +1 more source

Prognostic Impact of Estrogen and Progesterone Receptor Expression across Histological Subtypes and Clinical Factors in Epithelial Ovarian Cancer.

Gynecol Obstet Invest
Gasimli K, Wilke AM, Schmeil I, Gasimli B, Karn T, Becker S, Arsenic R, El-Balat A.   +7 more
europepmc   +1 more source

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The role of progesterone and the progesterone receptor in cancer

Expert Review of Endocrinology and Metabolism, 2017
There is an abundance of accumulating data strongly suggesting there is a key role for the progesterone receptor in the molecular events effecting the growth or containment of a variety of cancers. This knowledge should lead to novel new strategies to combat various cancers, including drugs classified as progesterone receptor modulators or monoclonal ...
exaly   +3 more sources

Progesterone receptor coactivators

Steroids, 2000
Progesterone action is mediated by intracellular progesterone receptors that regulate target gene transcription. Recently, numerous proteins termed coactivators have been identified that are recruited by the liganded progesterone receptor and enhance receptor-dependent transactivation.
Bert W O'Malley, Brian G Rowan
exaly   +3 more sources

Phosphorylation and Progesterone Receptor Function

The Journal of Steroid Biochemistry and Molecular Biology, 1994
Four phosphorylation sites have been identified in the chicken progesterone receptor. Two of these sites exhibit basal phosphorylation which is enhanced upon treatment with hormone and two of the sites are phosphorylated in response to hormone. Mutation of one of these hormone dependent sites, Ser530 to Ala530, causes a decrease in transcriptional ...
N. L. Weigel, W. Bai, Y. Zhang, C. A. Beck, D. P. Edwards, A. Poletti   +5 more
openaire   +4 more sources

Activation of Progesterone Receptor by ATP

European Journal of Biochemistry, 1981
Progesterone-receptor complex from freshly prepared hen oviduct cytosol acquired the ability to bind to isolated nuclei, DNA-cellulose and ATP-Sepharose when incubated with 5-10 mM ATP at 4 degrees C. The extent of this ATP-dependent activation was higher when compared with heat-activation achieved by warming the progesterone-receptor complex at 23 ...
V, Moudgil, V, Kruczak, T, Eessalu, C S, Paulose, M, Taylor, J, Hansen   +5 more
openaire   +3 more sources

Receptors for progesterone

Gynecologic Oncology, 1974
Abstract Coordinated estrogen- and progesterone-induced changes regulate biological functions of the endometrium. The uterine deciduoma reaction is used as a model in defining the mechanism of the progesterone-induced endometrial transformations. Uterine progesterone concentrations were determined by radioimmunoassay during three critical periods ...
B R, Rao, W G, Wiest
openaire   +2 more sources

Progesterone and progesterone receptors in reptiles

General and Comparative Endocrinology, 2002
The role of progesterone (P) has been most extensively studied in the female reproductive tissues (ovary, reproductive tract, mammary gland) and in the brain, in which it is an important regulator and modulator in conjunction with estradiol (E). In nonmammalian vertebrate species, less work has been done on P metabolites involved in ovulation.
Noemí, Custodia-Lora, Ian P, Callard
openaire   +2 more sources