Results 1 to 10 of about 399,116 (301)

Identification of multiple prognostic biomarker sets for risk stratification in SKCM [PDF]

Frontiers in Bioinformatics
IntroductionThe majority of available transcriptomics-related cancer prognosis studies strive to define one collection of biomarkers that can be used to predict high-risk patients. However, using a single biomarker profile could restrict its strength and
Shivani Malik, Ritu Tomer, Akanksha Arora, Gajendra P. S. Raghava   +3 more
doaj   +2 more sources

BioPETsurv: Methodology and open source software to evaluate biomarkers for prognostic enrichment of time-to-event clinical trials.

PLoS ONE, 2020
Biomarkers can be used to enrich a clinical trial for patients at higher risk for an outcome, a strategy termed "prognostic enrichment." Methodology is needed to evaluate biomarkers for prognostic enrichment of trials with time-to-event endpoints such as
Si Cheng, Kathleen F Kerr, Heather Thiessen-Philbrook, Steven G Coca, Chirag R Parikh   +4 more
doaj   +2 more sources

An appraisal of studies using mouse models to assist the biomarker discovery for sepsis prognosis

Heliyon, 2023
Introduction: Clinicians need reliable outcome predictors to improve the prognosis of septic patients. Mouse models are widely used in sepsis research. We aimed to review how mouse models were used to search for novel prognostic biomarkers of sepsis in ...
Yaqing Jiao, Cindy See Wai Tong, Timothy H. Rainer   +2 more
doaj   +1 more source

Computational analysis for identification of early diagnostic biomarkers and prognostic biomarkers of liver cancer based on GEO and TCGA databases and studies on pathways and biological functions affecting the survival time of liver cancer

BMC Cancer, 2021
Background Liver cancer is the sixth most commonly diagnosed cancer and the fourth most common cause of cancer death. The purpose of this work is to find new diagnostic biomarkers or prognostic biomarkers and explore the biological functions related to ...
Shiyong Gao, Jian Gang, Miao Yu, Guosong Xin, Huixin Tan   +4 more
doaj   +1 more source

Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study [PDF]

, 2018
Aims: To test the prognostic value of emerging biomarkers in the Reduction of Events by Darbepoetin Alfa in Heart Failure (RED-HF) trial. Methods and results: Circulating cardiac [N-terminal pro-B-type natriuretic peptide (NT-proBNP), and high ...
Alehagen, Arimoto, Balling, Bolignano, Cabassi, Dupont, Gaggin, Gravning, Grodin, Guisado Espartero, Haehling, Harrell, Jackson, Lassus, Lassus, Lok, Maisel, Maisel, McMurray, McMurray, Miller, Miller, Nagarajan, Park, Pascual-Figal, Pencina, Pencina, Pocock, Ponikowski, Rahimi, Rush, Shlipak, Swedberg, Tentzeris, Zamora   +34 more
core   +7 more sources

Outcomes based on plasma biomarkers in METEOR, a randomized phase 3 trial of cabozantinib vs everolimus in advanced renal cell carcinoma

BMC Cancer, 2021
Background In the phase 3 METEOR trial, cabozantinib improved progression-free survival (PFS) and overall survival (OS) versus everolimus in patients with advanced RCC after prior antiangiogenic therapy.
Thomas Powles, Toni K. Choueiri, Robert J. Motzer, Eric Jonasch, Sumanta Pal, Nizar M. Tannir, Sabina Signoretti, Rajesh Kaldate, Christian Scheffold, Evelyn Wang, Dana T. Aftab, Bernard Escudier, Daniel J. George   +12 more
doaj   +1 more source

Gene signature for prognosis in comparison of pancreatic cancer patients with diabetes and non-diabetes [PDF]

PeerJ, 2020
Background Pancreatic cancer (PC) has much weaker prognosis, which can be divided into diabetes and non-diabetes. PC patients with diabetes mellitus will have more opportunities for physical examination due to diabetes, while pancreatic cancer patients ...
Mingjun Yang, Boni Song, Juxiang Liu, Zhitong Bing, Yonggang Wang, Linmiao Yu   +5 more
doaj   +2 more sources

A Combined Long Noncoding RNA Signature as a Candidate Prognostic Biomarker for Ovarian Cancer

Frontiers in Oncology, 2021
AimsDysregulated long noncoding RNAs (lncRNAs) contributing to ovarian cancer (OC) development may serve as prognostic biomarker. We aimed to explore a lncRNA signature to serve as prognostic biomarker of OC.MethodsUnivariate Cox regression was conducted
Hui Li, Shuoer Wang, Shuoer Wang, Shuoer Wang, Qianlan Yao, Qianlan Yao, Qianlan Yao, Yan Liu, Jing Yang, Lun Xu, Lun Xu, Gong Yang, Gong Yang, Gong Yang   +13 more
doaj   +1 more source

Overexpressing PTTG family genes predict poor prognosis in kidney renal clear cell carcinoma

World Journal of Surgical Oncology, 2021
Background Pituitary tumor transforming genes (PTTG1, PTTG2, and PTTG3P) play key roles in the pathogenesis and development of human cancers. The studies show that overexpression of the PTTG genes is associated with tumor progression and migration ...
Yonghui Gui, Xueni Liu, Chao Wang, Peng Yang   +3 more
doaj   +1 more source

The Roles of Exosomes as Future Therapeutic Agents and Diagnostic Tools for Glioma

Frontiers in Oncology, 2021
Glioma is a common type of tumor originating in the brain. Glioma develops in the gluey supporting cells (glial cells) that surround and support nerve cells.
Xiaoben Wu, Xingbang Wang, Jing Wang, Yingying Hao, Fang Liu, Xin Wang, Lei Yang, Zhiming Lu   +7 more
doaj   +1 more source