Results 91 to 100 of about 187,404 (263)

Prognostic Value of EMT Gene Signature in Malignant Mesothelioma

open access: yesInternational Journal of Molecular Sciences, 2023
Malignant mesothelioma (MESO) consists of epithelioid, biphasic, and sarcomatoid subtypes with different epithelial–mesenchymal transition (EMT) phenotypes. We previously identified a panel of four MESO EMT genes correlating with an immunosuppressive tumor microenvironment and poor survival.
Wu, Licun   +9 more
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Identification and verification of a prognostic autophagy-related gene signature in hepatocellular carcinoma

open access: yesScientific Reports
This study aimed to investigate the potential of autophagy-related genes (ATGs) as a prognostic signature for HCC and explore their relationships with immune cells and immune checkpoint molecules.
Zhen Ma   +3 more
doaj   +1 more source

Development and validation of prognostic signatures of NAD+ metabolism and immune-related genes in colorectal cancer

open access: yesHeliyon
Background: Colorectal cancer (CRC) is a prevalent cause of death from malignant tumors. This study aimed to develop a nicotinamide adenine dinucleotide (NAD+) metabolism and immune-related prognostic signature, providing a theoretical foundation for ...
Tao Ye   +7 more
doaj   +1 more source

Identification and Validation of an EMT-Related LncRNA Signature for HNSCC to Predict Survival and Immune Landscapes

open access: yesFrontiers in Cell and Developmental Biology, 2022
Long noncoding RNAs (lncRNAs) are increasingly recognized as decisive factors in the progression of head and neck squamous cell carcinoma (HNSCC), and they participate in the epithelial–mesenchymal transformation (EMT) of HNSCC.
Chunyu Feng   +3 more
doaj   +1 more source

TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup. [PDF]

open access: yes, 2017
Purpose: Current clinical parameters do not stratify indolent from aggressive prostate cancer. Aggressive prostate cancer, defined by the progression from localized disease to metastasis, is responsible for the majority of prostate cancer–associated ...
Alshalalfa, Mohammed   +23 more
core   +2 more sources

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Prognosis analysis of necroptosis-related genes in colorectal cancer based on bioinformatic analysis

open access: yesFrontiers in Genetics, 2022
Background: Colorectal cancer (CRC) is one gastrointestinal malignancy, accounting for 10% of cancer diagnoses and cancer-related deaths worldwide each year.
Xiaojie Liang   +3 more
doaj   +1 more source

Characterisation of the immune-related transcriptome in resected biliary tract cancers [PDF]

open access: yes, 2017
Although biliary tract cancers (BTCs) are known to have an inflammatory component, a detailed characterisation of immune-related transcripts has never been performed.
Braconi, Chiara   +19 more
core   +3 more sources

Diagnostic, Prognostic and Therapeutic Value of Gene Signatures [PDF]

open access: yes, 2012
Diagnostic, prognostic, and therapeutic value of gene signatures / , Diagnostic, prognostic, and therapeutic value of gene signatures / , کتابخانه دیجیتال جندی شاپور ...
RUSSO, Antonio   +2 more
openaire   +2 more sources

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