Results 101 to 110 of about 1,264,892 (364)

The construction and analysis of a ferroptosis-related gene prognostic signature for pancreatic cancer

Aging, 2021
Ferroptosis is a regulated cell death nexus linking metabolism, redox biology and diseases including cancer. The aim of the present study was to identify a ferroptosis-related gene prognostic signature for pancreatic cancer (PCa) by systematic analysis ...
Peicheng Jiang, Feng Yang, Caifeng Zou, T. Bao, Mengmeng Wu, Dongqin Yang, S. Bu   +6 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A risk signature of four aging-related genes has clinical prognostic value and is associated with a tumor immune microenvironment in glioma [PDF]

, 2021
Haitao Luo, Chuming Tao, Xiaoyan Long, Kai Huang, Xingen Zhu   +4 more
openalex   +1 more source

Identification and Validation of Six Autophagy-related Long Non-coding RNAs as Prognostic Signature in Colorectal Cancer

International Journal of Medical Sciences, 2021
Colorectal cancer (CRC) is a commonly occurring tumour with poor prognosis. Autophagy-related long non-coding RNAs (lncRNAs) have received much attention as biomarkers for cancer prognosis and diagnosis.
Lin Cheng, T. Han, Zheyu Zhang, Pengji Yi, Chunhu Zhang, Sifang Zhang, Weijun Peng   +6 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Identification of a prognostic immune signature for cervical cancer to predict survival and response to immune checkpoint inhibitors

OncoImmunology, 2019
Cervical cancer (CC) is a leading cause of cancer-related death in women. Limited studies have investigated whether immune-related genes (IRGs) or tumor immune microenvironment (TIME) could be indicators for CC prognoses.
Si Yang, Ying Wu, Yujiao Deng, Linghui Zhou, Pengtao Yang, Yi Zheng, Dai Zhang, Zhen Zhai, Na Li, Qian Hao, Dingli Song, Huafeng Kang, Zhijun Dai   +12 more
doaj   +1 more source

Prognosis analysis of necroptosis-related genes in colorectal cancer based on bioinformatic analysis

Frontiers in Genetics, 2022
Background: Colorectal cancer (CRC) is one gastrointestinal malignancy, accounting for 10% of cancer diagnoses and cancer-related deaths worldwide each year.
Xiaojie Liang, Zhaoxiang Cheng, Xinhao Chen, Jun Li   +3 more
doaj   +1 more source

Identification and Validation of Immune-Related LncRNA Prognostic Signature for Lung Adenocarcinoma

Frontiers in Genetics, 2021
This study aimed to establish a prognostic risk model for lung adenocarcinoma (LUAD). We firstly divided 535 LUAD samples in TCGA-LUAD into high-, medium-, and low-immune infiltration groups by consensus clustering analysis according to immunological ...
Guomin Wu, Qi-Hua Wang, Ting Zhu, Linhai Fu, Zhupeng Li, Yuanlin Wu, Chu Zhang   +6 more
semanticscholar   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Identification and verification of a prognostic autophagy-related gene signature in hepatocellular carcinoma

Scientific Reports
This study aimed to investigate the potential of autophagy-related genes (ATGs) as a prognostic signature for HCC and explore their relationships with immune cells and immune checkpoint molecules.
Zhen Ma, Mali Chen, XiaoLong Liu, Hongbin Cui   +3 more
doaj   +1 more source