Results 31 to 40 of about 54,878 (125)
Inferring diagnostic and prognostic gene expression signatures across WHO glioma classifications: A network-based approach [PDF]
Tumor heterogeneity is a challenge to designing effective and targeted therapies. Glioma-type identification depends on specific molecular and histological features, which are defined by the official WHO classification CNS. These guidelines are constantly updated to support the diagnosis process, which affects all the successive clinical decisions.
arxiv
Identification of a prognostic six-immune-gene signature and a nomogram model for uveal melanoma
Background To identify an immune-related prognostic signature and find potential therapeutic targets for uveal melanoma. Methods The RNA-sequencing data obtained from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets.
Binghua Yang+4 more
doaj +1 more source
A Novel Immune-Related Prognostic Signature for Thyroid Carcinoma
Background: Recent studies have confirmed that immune-associated genes perform a crucial function in recurrence and metastasis of thyroid carcinoma. A reliable immune-related prognostic signature for patients with thyroid cancer is needed.
Yuanbo Xue MD, Jing Li MD, Xiubo Lu MD
doaj +1 more source
Development and Validation of a 9-Gene Prognostic Signature in Patients With Multiple Myeloma
Background: Multiple myeloma (MM) is one of the most common types of hematological malignance, and the prognosis of MM patients remains poor.Objective: To identify and validate a genetic prognostic signature in patients with MM.Methods: Co-expression ...
Xiao-Ping Liu+5 more
doaj +1 more source
Development and internal validation of a nine-lncRNA prognostic signature for prediction of overall survival in colorectal cancer patients [PDF]
Background Colorectal cancer remains a serious public health problem due to the poor prognosis. In the present study, we attempted to develop and validate a prognostic signature to predict the individual mortality risk in colorectal cancer patients ...
Zhiqiao Zhang+7 more
doaj +2 more sources
Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma
Introduction: Increasing evidences have shown that hypoxia and the immune microenvironment play vital roles in the development of osteosarcoma. However, reliable gene signatures based on the combination of hypoxia and the immune status for prognostic ...
Wenshuo Zhang+5 more
doaj +1 more source
Cervical cancer (CC) is a leading cause of cancer-related death in women. Limited studies have investigated whether immune-related genes (IRGs) or tumor immune microenvironment (TIME) could be indicators for CC prognoses.
Si Yang+12 more
doaj +1 more source
Background Increasing evidences supported the association between long non-coding RNA (lncRNA) and disease free survival in gastric cancer (GC) patients.
Canchang Cheng+4 more
doaj +1 more source
Prognosis analysis of necroptosis-related genes in colorectal cancer based on bioinformatic analysis
Background: Colorectal cancer (CRC) is one gastrointestinal malignancy, accounting for 10% of cancer diagnoses and cancer-related deaths worldwide each year.
Xiaojie Liang+3 more
doaj +1 more source
Background Rectal cancer is a common cancer worldwide and lacks effective prognostic markers. The development of prognostic markers by computational pathology methods has attracted increasing attention. This paper aims to construct a prognostic signature
Xuezhi Zhou+11 more
doaj +1 more source