Results 31 to 40 of about 187,404 (263)

Identification of Potential Prognostic Long Non-Coding RNA Biomarkers for Predicting Survival in Patients with Hepatocellular Carcinoma

Cellular Physiology and Biochemistry, 2018
Background/Aims: The aim of the current study was to identify potential prognostic long non-coding RNA (lncRNA) biomarkers for predicting survival in patients with hepatocellular carcinoma (HCC) using The Cancer Genome Atlas (TCGA) dataset and ...
Xiwen Liao, Chengkun Yang, Rui Huang, Chuangye Han, Tingdong Yu, Ketuan Huang, Xiaoguang Liu, Long Yu, Guangzhi Zhu, Hao Su, Xiangkun Wang, Wei Qin, Jianlong Deng, Xianmin Zeng, Xinping Ye, Tao Peng   +15 more
doaj   +1 more source

Development and validation of a robust immune-related prognostic signature in early-stage lung adenocarcinoma

Journal of Translational Medicine, 2020
Background The incidence of stage I and stage II lung adenocarcinoma (LUAD) is likely to increase with the introduction of annual screening programs for high-risk individuals. We aimed to identify a reliable prognostic signature with immune-related genes
Pancheng Wu, Yi Zheng, Yanyu Wang, Yadong Wang, Naixin Liang   +4 more
doaj   +1 more source

Model selection for prognostic time-to-event gene signature discovery with applications in early breast cancer data [PDF]

, 2013
Model selection between competing models is a key consideration in the discovery of prognostic multigene signatures. The use of appropriate statistical performance measures as well as verification of biological significance of the signatures is ...
Ahdesmaeki, Miika, Davison, Timothy S., Harkin, D. Paul, Kennedy, Richard D., Lancashire, Lee, Proutski, Vitali, Wilson, Claire   +6 more
core   +1 more source

Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer

Frontiers in Oncology, 2022
BackgroundEnergy metabolism has been considered as one of the novel features of neoplasms. This study aimed to establish the prognostic signature for pancreatic cancer (PC) based on metabolism-related genes (MRGs).MethodsWe obtained MRGs from the ...
Hui Chen, Fuqiang Zu, Taofei Zeng, Ziang Chen, Jinhong Wei, Peng Liu, Zeyu Li, Lei Zhou, Huaitao Wang, Hao Tan, Xiaodong Tan   +10 more
doaj   +1 more source

EarlyR: A Robust Gene Expression Signature for Predicting Outcomes of Estrogen Receptor–Positive Breast Cancer [PDF]

, 2018
Introduction Early stage estrogen receptor (ER)-positive breast cancer may be treated with chemotherapy in addition to hormone therapy. Currently available molecular signatures assess the risk of recurrence and the benefit of chemotherapy; however ...
Badve, Sunil S., Buechler, Steven A., Gökmen-Polar, Yesim   +2 more
core   +1 more source

Survival prediction in mesothelioma using a scalable lasso regression model: instructions for use and initial performance using clinical predictors [PDF]

, 2018
Introduction: Accurate prognostication is difficult in malignant pleural mesothelioma (MPM). We developed a set of robust computational models to quantify the prognostic value of routinely available clinical data, which form the basis of published MPM ...
Blyth, Kevin G., Bylesjo, Max, Halligan, Daniel L., Kidd, Andrew C., McGettrick, Michael, Tsim, Selina   +5 more
core   +1 more source

A prognostic gene expression signature in infratentorial ependymoma [PDF]

Acta Neuropathologica, 2012
Patients with ependymoma exhibit a wide range of clinical outcomes that are currently unexplained by clinical or histological factors. Little is known regarding molecular biomarkers that could predict clinical behavior. Since recent data suggest that these tumors display biological characteristics according to their location (cerebral vs ...
K. Wani, T. S. Armstrong, E. Vera Bolanos, A. Raghunathan, D. Ellison, R. Gilbertson, B. Vaillant, S. Goldman, R. J. Packer, M. Fouladi, I. Pollack, T. Mikkelsen, M. Prados, A. Omuro, SOFFIETTI, Riccardo, A. Ledoux, C. Wilson, L. Long, M. R. Gilbert, K. Aldape, F. t. Collaborative   +20 more
openaire   +3 more sources

Construction of a prognostic signature for serous ovarian cancer based on lactate metabolism-related genes

Frontiers in Oncology, 2022
BackgroundThe key biochemical feature of malignant tumor is the conversion of energy metabolism from oxidative phosphorylation to glycolysis, which provides sufficient capacity and raw materials for tumor cell rapid growth.
Jiangdong Xiang, Rongjia Su, Sufang Wu, Lina Zhou   +3 more
doaj   +1 more source

Circular RNAs in Clear Cell Renal Cell Carcinoma: Their Microarray-Based Identification, Analytical Validation, and Potential Use in a Clinico-Genomic Model to Improve Prognostic Accuracy [PDF]

, 2019
Circular RNAs (circRNAs) may act as novel cancer biomarkers. However, a genome-wide evaluation of circRNAs in clear cell renal cell carcinoma (ccRCC) has yet to be conducted. Therefore, the objective of this study was to identify and validate circRNAs in
Erbersdobler, Andreas, Fendler, Annika, Franz, Antonia, Jung, Klaus, Jung, Monika, Kilic, Ergin, Ralla, Bernhard, Rochow, Hannah, Stephan, Carsten, Weickmann, Sabine   +9 more
core   +2 more sources

Integrated Analysis to Obtain Potential Prognostic Signature in Glioblastoma [PDF]

Frontiers in Integrative Neuroscience, 2022
Glioblastoma multiforme (GBM) is the most malignant and multiple tumors of the central nervous system. The survival rate for GBM patients is less than 15 months. We aimed to uncover the potential mechanism of GBM in tumor microenvironment and provide several candidate biomarkers for GBM prognosis. In this study, ESTIMATE analysis was used to divide the
Jia-Qi Chen, Jia-Qi Chen, Nuo Zhang, Zhi-Lin Su, Hui-Guo Qiu, Xin-Guo Zhuang, Zhi-hua Tao   +6 more
openaire   +3 more sources