Expression and prognostic value of prohibitin in gastrointestinal cancers based on bioinformatics
陆军军医大学学报Objective To explore the expression of prohibitin (PHB) in tumor tissues and analyze its effect on the prognosis of patients with digestive system malignant tumor (DT) and its mechanism.
LI Xiaofeng, LIU Xixi, SONG Ziqing
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Alms1 KO Rat: A New Model of Cardiometabolic Syndrome With Spontaneous Hypertension
Acta Physiologica, Volume 242, Issue 3, March 2026.ABSTRACT Alström syndrome 1 (ALMS1) is a protein linked to Alström syndrome, a rare genetic disorder characterized by obesity, insulin resistance, hyperinsulinemia, and hypertension. Genetic studies have further associated Alms1 with hypertension in human populations. However, the precise mechanisms by which ALMS1 regulates metabolic and cardiovascular
Ankita B. Jaykumar +6 more
wiley +1 more source
Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets [PDF]
, 2019 © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.
Antwi-Baffour, Samuel +5 more
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Skin Colour in Salamanders Is Modulated by Both Epitranscriptomic Methylation and Gene Expression
Molecular Ecology, Volume 35, Issue 6, March 2026.ABSTRACT Animal colouration is a key trait in organismal biology, being involved in natural and sexual selection, competition, and communication. Amphibians use their highly diverse colouration in many ecological interactions, but the molecular bases of their colour variation are less well understood than in other vertebrate systems. While the genetic,
Nicholas Strowbridge +3 more
wiley +1 more source
Effects of nanoparticles on murine macrophages [PDF]
, 2010 Metallic nanoparticles are more and more widely used in an increasing number of applications. Consequently, they are more and more present in the environment, and the risk that they may represent for human health must be evaluated.
A van Dorsselaer +11 more
core +4 more sources
Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells. [PDF]
PLoS ONE, 2012 Increase in mitochondrial biogenesis has been shown to accompany brown and white adipose cell differentiation. Prohibitins (PHBs), comprised of two evolutionarily conserved proteins, prohibitin-1 (PHB1) and prohibitin-2 (PHB2), are present in a high ...
Dong Liu +9 more
doaj +1 more source
Silencing a prohibitin alters plant development and senescence [PDF]
The Plant Journal, 2005 SummaryProhibitins, highly conserved mitochondrial proteins, have been shown to play important roles in cell cycling and senescence in animals and yeast. Sequences with high similarity to prohibitins have been identified in a number of plant species, but their function has not yet been demonstrated. The deduced amino acid sequences of PhPHB1 and PhPHB2,
Jen-Chih, Chen +2 more
openaire +2 more sources
A Rare NPHS2 Mutation (E130K) in Hereditary Steroid‐Resistant Nephrotic Syndrome: A Case Report
Case Reports in Nephrology, Volume 2026, Issue 1, 2026.Hereditary steroid‐resistant nephrotic syndrome (HSRNS) due to mutations in the NPHS2 gene (encoding podocin) is a rare genetic condition that typically presents in childhood. We report a case of a 2‐year‐and‐8‐month‐old male, the seventh child of consanguineous parents, who presented with recurrent fever, febrile tonic‐clonic seizures, and periorbital
Ramzi Hmedan Mujahed +7 more
wiley +1 more source
Nano ExpressAnti-obesity drugs are limited in their application due to poor drug specificity, efficacy, and bystander side effects. The study reports on the use of bi-functionalized gold nanoparticles (AuNPs) to improve the selectivity and efficacy of therapeutic ...
Nicole R S Sibuyi +6 more
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Immunoproteomic to identify antigens in the intestinal mucosa of Crohn's disease patients. [PDF]
PLoS ONE, 2013 Incidences of Crohn disease (CD) have increased significantly in the last decade. Immunoproteomics are a promising method to identify biomarkers of different diseases. In the present study, we used immunoproteomics to study proteins of intestinal mucosal
Zheng Zhou +6 more
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