Results 71 to 80 of about 7,558 (163)
Mitochondrial–Nuclear Communication by Prohibitin Shuttling under Oxidative Stress
Mitochondrial–nuclear communication is critical for maintaining mitochondrial activity under stress conditions. Adaptation of the mitochondrial–nuclear network to changes in the intracellular oxidation and reduction milieu is critical for the survival of
Beth M. Elledge (2164291) +6 more
core +1 more source
Skp2 and Skp2B team up against Rb and p53
The Skp2 locus encodes two proteins, Skp2 and Skp2B. The role of Skp2 in the ubiquitin-dependent degradation of key regulators of the retinoblastoma protein pathway has been well established.
Germain Doris
doaj +1 more source
Identification and Analysis of Prohibitin in B16 Mouse Melanoma Cells [PDF]
Prohibitin, a highly conserved protein found in eukaryotic cells, has been found in recent years to possess a wide variety of functions in the cell.
Francis, Christopher
core
Prohibitin: targeting peptide coupled to ovarian cancer, luteinization and TGF-β pathways
Background Ovarian epithelial tumor (OET) is a silent disease of late diagnosis and poor prognosis. Currently treatment options are limited and patient response to treatment is difficult to predict so there is a serious need to delineate the real ...
Nour M. El-Etreby +2 more
doaj +1 more source
Prohibitin: a potential therapeutic target in tyrosine kinase signaling
Prohibitin is a pleiotropic protein that has roles in fundamental cellular processes, such as cellular proliferation and mitochondrial housekeeping, and in cell- or tissue-specific functions, such as adipogenesis and immune cell functions.
Suresh Mishra +2 more
core +1 more source
Background. COVID-19 pandemic is accompanied by a considerable number of morbidity cases among pregnant women. Certain knowledge has been accumulated about the histopathological features of the placenta during SARS-CoV-2 infection.
G.S. Manasova, Y.O. Stasii
doaj +1 more source
To evaluate microbeam radiation therapy (MRT), for brain tumor treatment, the bystander effect in nonirradiated companion animals was investigated.
Richard Smith +9 more
doaj +1 more source
SARS‐CoV‐2 and Cancer Biology: Exploring the Mechanistic Links
ABSTRACT Background Five years after the emergence of SARS‐CoV‐2 and the declaration of the COVID‐19 pandemic, the long‐term implications of COVID‐19 for cancer biology remain incompletely understood. Beyond the major disruptions in cancer screening, diagnosis, and treatment observed worldwide, increasing attention has focused on whether SARS‐CoV‐2 ...
Andrea Orue +2 more
wiley +1 more source
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
Background Mitochondria are dynamic organelles that undergo fission and fusion. During cell stress, mitochondrial dynamics shift to fission, leading to mitochondrial fragmentation, membrane leakage, and apoptosis.
Han-Fei Ding +25 more
core +1 more source

