Results 71 to 80 of about 7,558 (163)

Mitochondrial–Nuclear Communication by Prohibitin Shuttling under Oxidative Stress

open access: yes, 2016
Mitochondrial–nuclear communication is critical for maintaining mitochondrial activity under stress conditions. Adaptation of the mitochondrial–nuclear network to changes in the intracellular oxidation and reduction milieu is critical for the survival of
Beth M. Elledge (2164291)   +6 more
core   +1 more source

Skp2 and Skp2B team up against Rb and p53

open access: yesCell Division, 2011
The Skp2 locus encodes two proteins, Skp2 and Skp2B. The role of Skp2 in the ubiquitin-dependent degradation of key regulators of the retinoblastoma protein pathway has been well established.
Germain Doris
doaj   +1 more source

Identification and Analysis of Prohibitin in B16 Mouse Melanoma Cells [PDF]

open access: yes, 2008
Prohibitin, a highly conserved protein found in eukaryotic cells, has been found in recent years to possess a wide variety of functions in the cell.
Francis, Christopher
core  

Prohibitin: targeting peptide coupled to ovarian cancer, luteinization and TGF-β pathways

open access: yesJournal of Ovarian Research, 2017
Background Ovarian epithelial tumor (OET) is a silent disease of late diagnosis and poor prognosis. Currently treatment options are limited and patient response to treatment is difficult to predict so there is a serious need to delineate the real ...
Nour M. El-Etreby   +2 more
doaj   +1 more source

Prohibitin: a potential therapeutic target in tyrosine kinase signaling

open access: yes, 2017
Prohibitin is a pleiotropic protein that has roles in fundamental cellular processes, such as cellular proliferation and mitochondrial housekeeping, and in cell- or tissue-specific functions, such as adipogenesis and immune cell functions.
Suresh Mishra   +2 more
core   +1 more source

Immunohistochemical assessment of epidermal growth factor receptor and prohibitin expression in “post-COVID” placentas: results of a comparative cross-sectional study

open access: yesРепродуктивная эндокринология
Background. COVID-19 pandemic is accompanied by a considerable number of morbidity cases among pregnant women. Certain knowledge has been accumulated about the histopathological features of the placenta during SARS-CoV-2 infection.
G.S. Manasova, Y.O. Stasii
doaj   +1 more source

Homogenous and Microbeam X-Ray Radiation Induces Proteomic Changes in the Brains of Irradiated Rats and in the Brains of Nonirradiated Cage Mate Rats

open access: yesDose-Response, 2018
To evaluate microbeam radiation therapy (MRT), for brain tumor treatment, the bystander effect in nonirradiated companion animals was investigated.
Richard Smith   +9 more
doaj   +1 more source

SARS‐CoV‐2 and Cancer Biology: Exploring the Mechanistic Links

open access: yesCancer Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background Five years after the emergence of SARS‐CoV‐2 and the declaration of the COVID‐19 pandemic, the long‐term implications of COVID‐19 for cancer biology remain incompletely understood. Beyond the major disruptions in cancer screening, diagnosis, and treatment observed worldwide, increasing attention has focused on whether SARS‐CoV‐2 ...
Andrea Orue   +2 more
wiley   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, Volume 4, Issue 4, July 2026.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis

open access: yes, 2019
Background Mitochondria are dynamic organelles that undergo fission and fusion. During cell stress, mitochondrial dynamics shift to fission, leading to mitochondrial fragmentation, membrane leakage, and apoptosis.
Han-Fei Ding   +25 more
core   +1 more source

Home - About - Disclaimer - Privacy