Results 51 to 60 of about 7,558 (163)
Expression of prohibitin in rat seminiferous epithelium
, 1993 Subtractive hybridization was used to isolate cDNAs highly expressed in stages IX-XI of the cycle of the seminiferous epithelium in the rat. One of the cloned cDNAs was sequenced and shown to be homologous to a previously described cDNA encoding rat ...
Griswold, M D +3 more
core +1 more source
Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse
Experimental Physiology, EarlyView.Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley +1 more source
The prohibitin-binding compound fluorizoline inhibits mitophagy in cancer cells
Oncogenesis, 2021 Fluorizoline is a prohibitin-binding compound that triggers apoptosis in several cell lines from murine and human origin, as well as in primary cells from hematologic malignancies by inducing the integrated stress response and ER stress. Recently, it was
Sonia Núñez-Vázquez +9 more
doaj +1 more source
Clinical and Translational Medicine, Volume 16, Issue 10, October 2026.This review highlights protein lactylation as a metabolic‐epigenetic regulator linking lactate reprogramming to programmed cell death. By modulating histone and non‐histone targets, lactylation reshapes cell fate decisions and represents a promising biomarker and therapeutic target in human diseases.
Yue Chen +8 more
wiley +1 more source
Prohibitin affects the conformation of p53.
, 2013 A) MCF-7 cells were transfected with siRNA against prohibitin for 48 hours. The inhibition of prohibitin expression was confirmed and the levels of p53 determined by immunoblot.
James J. Manfredi (346732) +4 more
core +1 more source
Expression and prognostic value of prohibitin in gastrointestinal cancers based on bioinformatics
陆军军医大学学报Objective To explore the expression of prohibitin (PHB) in tumor tissues and analyze its effect on the prognosis of patients with digestive system malignant tumor (DT) and its mechanism.
LI Xiaofeng, LIU Xixi, SONG Ziqing
doaj +1 more source
The Plant Genome, Volume 19, Issue 3, September 2026.Abstract Southern corn leaf blight (SCLB) is caused by the fungal pathogen Bipolaris maydis (syn. Cochliobolus heterostrophus Drechsler) and is a common disease of fall crops of sweet corn. Phenotyping for SCLB resistance is performed through visual scoring, which is subjective and may limit genetic gain for this quantitative trait.
Darlon V. Lantican +9 more
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2019 Vi capsular polysaccharide (Vi) is a major virulence factor of human typhoid-causing pathogen Salmonella enterica serovar Typhi (S. Typhi). It distinguishes S. Typhi from closely related non-typhoidal Salmonella serovars such as S.
Farhat Parween +2 more
doaj +1 more source
Nature Communications, 2021 How ROS levels are regulated in cancer stem cells and their contribution to cancer resistance is currently not clear. Here, the authors show that prohibitin regulates mitochondrial ROS production stabilizing the peroxidase PRDX3 and this accounts for ...
Haohao Huang +23 more
doaj +1 more source
Aging Cell, Volume 25, Issue 9, September 2026.Findings from this study suggest that aging is accompanied by altered skeletal muscle mitochondrial redox regulation and exercise responsiveness, with decreased mtDNA copy number, increased mtDNA mutation deletion frequency, and selective redox remodeling of key mitochondrial proteins representing potential contributors to these changes. ABSTRACT Redox
Bradley A. Ruple +11 more
wiley +1 more source