Results 11 to 20 of about 11,901 (220)
Prohibitin and mitochondrial biology [PDF]
Trends in Endocrinology & Metabolism, 2009 8 pages, 2 figures.--PMID: 19733482 [PubMed]Prohibitins are ubiquitous, evolutionarily conserved proteins that are mainly localized in mitochondria. The mitochondrial prohibitin complex comprises two subunits, PHB1 and PHB2.
Artal-Sanz, Marta +1 more
core +6 more sources
The Role of Prohibitin-2 in Diseases
Frontiers in Bioscience-Landmark, 2023 Prohibitin-2 (PHB2) is a conserved protein in mitochondria that regulates various biological processes, including cell cycle, proliferation, apoptosis, transcription, signal transduction, and mitochondrial ridge morphogenesis.
Fang Liu +3 more
doaj +3 more sources
Imaging Findings of Paratesticular Adenomatoid Tumor. [PDF]
Clin Case RepABSTRACT Paratesticular adenomatoid tumors are benign growths usually found near the epididymis. They often show no symptoms and appear as hyperechoic masses on ultrasound. Magnetic resonance imaging helps in difficult cases. Surgical removal is curative with minimal recurrence risk.
Liu W, Yuan Z, Liang L, Leng X.
europepmc +2 more sources
From isolation to insights: mitochondrial complex I in the diatom Phaeodactylum tricornutum. [PDF]
Plant JSUMMARY Diatoms are among the most ecologically successful microalgae, contributing significantly to marine primary production and global carbon cycling. Their distinctive metabolic architecture, shaped by a complex evolutionary history involving secondary endosymbiosis, includes a highly compartmentalized cell organization and unique metabolic ...
Berdun F +7 more
europepmc +2 more sources
Current Biology, 2017 Tatsuta and Langer introduce prohibitins, membrane scaffolding proteins found predominantly in mitochondria.
Tatsuta, T., Langer, T.
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Mitophagy: Permitted by Prohibitin [PDF]
Current Biology, 2017 Autophagic responses specific for damaged or superfluous mitochondria are crucial for the maintenance of cellular and organismal homeostasis. Recent data demonstrate that components of the inner mitochondrial membrane that are unmasked upon outer membrane permeabilization facilitate the autophagic destruction of the organelle.
Lorenzo, Galluzzi +2 more
openaire +2 more sources
Ras-Raf Signaling Needs Prohibitin [PDF]
Cell Cycle, 2005 Prohibitin has been connected to diverse cellular functions including cell cycle control, senescence, apoptosis and stabilization of mitochondrial proteins. By employing a loss of function approach using siRNAs we have demonstrated an unexpected role of PHB in the activation of Raf/MEK/ERK pathway by active Ras and in modulating epithelial cell ...
Rajalingam, K., Rudel, T.
openaire +3 more sources
In situ architecture of the human prohibitin complex. [PDF]
Nat Cell BiolAbstractProhibitins are a highly conserved family of proteins that have been implicated in a variety of functions including mitochondrial stress signalling and housekeeping, cell cycle progression, apoptosis, lifespan regulation and many others1, 2.
Lange F +7 more
europepmc +7 more sources
Prohibitin-mediated lifespan and mitochondrial stress implicate SGK-1, insulin/IGF and mTORC2 in C. elegans. [PDF]
PLoS ONE, 2014 Lifespan regulation by mitochondrial proteins has been well described, however, the mechanism of this regulation is not fully understood. Amongst the mitochondrial proteins profoundly affecting ageing are prohibitins (PHB-1 and PHB-2).
Roxani Gatsi +5 more
doaj +1 more source
Microbiology Spectrum, 2023 Theileriosis is a tick-borne disease caused by Theileria annulata, an intracellular parasite that belongs to the phylum Apicomplexa. The infective forms of the parasite to cattle are sporozoites that are introduced into the host when the infected ticks ...
Prasanna Babu Araveti +5 more
doaj +1 more source