Results 21 to 30 of about 7,558 (163)

Expression and co-location of prohibitin genes in salt-tolerance QTLs in rice (Oryza sativa)

The Indian Journal of Agricultural Sciences, 2020
Prohibitin proteins are involved in diverse biological functions including cell cycle regulation, mitochondrial activity, apoptosis, hormonal signalling and so on.
Rakesh Bhowmick, Sushma Tiwari, Vandana Rai, Nagendra Kumar Singh   +3 more
doaj   +1 more source

Inner mitochondrial membrane protein Prohibitin 1 mediates Nix-induced, Parkin-independent mitophagy

Scientific Reports, 2023
Autophagy of damaged mitochondria, called mitophagy, is an important organelle quality control process involved in the pathogenesis of inflammation, cancer, aging, and age-associated diseases.
Kibrom M. Alula, Yaritza Delgado-Deida, Rosemary Callahan, Andreas Till, Lucia Underwood, Winston E. Thompson, Rhonda F. Souza, Themistocles Dassopoulos, Joseph Onyiah, K. Venuprasad, Arianne L. Theiss   +10 more
doaj   +1 more source

Studies on Fortilin-Prohibitin Interaction [PDF]

, 2013
: Apoptosis, programmed cell death, is a tightly regulated process that occurs in development, in tissue maintenance and turnover, and in regulating the immune system.
Doan, Hung 1982-
core   +2 more sources

Mitochondrial Disruption by Amyloid Beta 42 Identified by Proteomics and Pathway Mapping

Cells, 2021
Alzheimer’s disease (AD) is marked by chronic neurodegeneration associated with the occurrence of plaques containing amyloid β (Aβ) proteins in various parts of the human brain.
Patricia Sinclair, Ancha Baranova, Nadine Kabbani   +2 more
doaj   +1 more source

Prohibitins are required for cancer cell proliferation and adhesion.

PLoS ONE, 2010
Prohibitin 1 (PHB1) is a highly conserved protein that together with its homologue prohibitin 2 (PHB2) mainly localizes to the inner mitochondrial membrane.
Claudia Sievers, Gwendolyn Billig, Kathleen Gottschalk, Thomas Rudel   +3 more
doaj   +1 more source

Discovery of PHB1 as a Novel Candidate Gene in Dominant Optic Atrophy. [PDF]

Clin Genet
A heterozygous PHB1 missense variant (p.Ser147Phe) segregates with autosomal dominant optic atrophy in a multi‐generation family. Structural and cellular analyses suggest altered mitochondrial dynamics, identifying PHB1 as a novel candidate gene for hereditary optic neuropathy. ABSTRACT Hereditary optic neuropathies comprise a genetically heterogeneous
Volk M, Maver A, Vidmar MJ, Trošt N, Višnjar T, Fakin A, Kovač L, Habjan MŠ, Malinar L, Pajić SP, Jerman UD, Romih R, Hawlina M, Peterlin B.   +13 more
europepmc   +2 more sources

Proteomic analysis of the rat ovary following chronic low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) [PDF]

, 2009
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a ubiquitously distributed endocrine-disrupting chemical and reproductive toxicant. In order to elucidate low-dose TCDD-mediated effects on reproductive or endocrine functions, female Sprague-Dawley rats were
Chen, Xi, Chun-mei Zhang, Jing Liu, Ma, X.M., Zhang, C.M., Zhao, L.J., Zhang, Chun-mei, Chen, X., Li-jun Zhao, Sun, M., Ma, Xiao-ming, Coenraads, P.J., Tang, N.J., Liu, J., Tang, Nai-jun, Liu, Jing, Zhao, Li-jun, Xi Chen, Pieter-Jan Coenraads, Ma, S.W., Shi-wei Ma, Min Sun, Coenraads, Pieter-Jan, Xiao-ming Ma, Sun, Min, Ma, Shi-wei, Nai-jun Tang   +26 more
core   +2 more sources

Prohibitin is overexpressed in Huh-7-HCV and Huh-7.5-HCV cells harboring in vitro transcribed full-length hepatitis C virus RNA

Virology Journal, 2011
Background Currently, up-regulated proteins and apoptosis in hepatitis C is a hot topic in exploring the pathogenic mechanism of Heptitis C Virus(HCV). Some recent studies shows that prohibitin is overexpressed in cells expressing HCV core proteins, and ...
Wang Wen-Jun, Jia Zhan-Sheng, Ma Li, Xun Meng, Yang E, Sun Ming-Zhu, Dang Shuang-Suo, Jia Xiao-Li   +7 more
doaj   +1 more source

Prohibitin Protects Pulmonary Microvascular Endothelial Cells Against Cigarette Smoke Extract-Induced Cell Apoptosis and Inflammation

International Journal of COPD, 2022
Yating Peng,1– 3 Wei Cheng,1– 3 Jiaxi Duan,1– 3 Yiyang Zhao,1– 3 Zijing Zhou,1– 3 Aiyuan Zhou,1– 3 Minhua Deng,1– 4 Hong Peng,1– 3 Ruoyun Ouyang,1– 3 Yan Chen,1– 3 Ping Chen1– 3 1Department of Pulmonary and Critical Care Medicine, Second Xiang Ya ...
Peng Y, Cheng W, Duan J, Zhao Y, Zhou Z, Zhou A, Deng M, Peng H, Ouyang R, Chen Y, Chen P   +10 more
doaj  

Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells

eLife, 2021
Dysfunction of the mitochondrial electron transport chain (mETC) is a major cause of human mitochondrial diseases. To identify determinants of mETC function, we screened a genome-wide human CRISPRi library under oxidative metabolic conditions with ...
Maxence Le Vasseur, Jonathan Friedman, Marco Jost, Jiawei Xu, Justin Yamada, Martin Kampmann, Max A Horlbeck, Michelle R Salemi, Brett S Phinney, Jonathan S Weissman, Jodi Nunnari   +10 more
doaj   +1 more source