Results 21 to 30 of about 7,232 (211)
Current Biology, 2017 Tatsuta and Langer introduce prohibitins, membrane scaffolding proteins found predominantly in mitochondria.
Tatsuta, T., Langer, T.
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The Role of Prohibitin-2 in Diseases
Frontiers in Bioscience-Landmark, 2023 Prohibitin-2 (PHB2) is a conserved protein in mitochondria that regulates various biological processes, including cell cycle, proliferation, apoptosis, transcription, signal transduction, and mitochondrial ridge morphogenesis. Recently, there has been growing interest in the biological function of PHB2.
Fang Liu +3 more
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The emerging roles of prohibitins in folliculogenesis [PDF]
Frontiers in Bioscience, 2012 Prohibitins are members of a highly conserved eukaryotic protein family containing the stomatin/prohibitin/flotillin/HflK/C (SPFH) domain (also known as the prohibitin (PHB) domain) found in divergent species from prokaryotes to eukaryotes. Prohibitins are found in unicellular eukaryotes, fungi, plants, animals and humans.
Indrajit, Chowdhury +5 more
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Prohibitin and mitochondrial biology [PDF]
Trends in Endocrinology & Metabolism, 2009 Prohibitins are ubiquitous, evolutionarily conserved proteins that are mainly localized in mitochondria. The mitochondrial prohibitin complex comprises two subunits, PHB1 and PHB2. These two proteins assemble into a ring-like macromolecular structure at the inner mitochondrial membrane and are implicated in diverse cellular processes: from ...
Artal-Sanz, Marta +1 more
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Mitophagy: Permitted by Prohibitin [PDF]
Current Biology, 2017 Autophagic responses specific for damaged or superfluous mitochondria are crucial for the maintenance of cellular and organismal homeostasis. Recent data demonstrate that components of the inner mitochondrial membrane that are unmasked upon outer membrane permeabilization facilitate the autophagic destruction of the organelle.
Lorenzo, Galluzzi +2 more
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Prohibitins in neurodegeneration and mitochondrial homeostasis
Frontiers in Aging, 2022 The incidence of age-related neurodegenerative disorders has risen with the increase of life expectancy. Unfortunately, the diagnosis of such disorders is in most cases only possible when the neurodegeneration status is already advanced, and symptoms are evident.
Jesus Fernandez-Abascal +3 more
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The role of prohibitin in cell signaling [PDF]
The FEBS Journal, 2010 Prohibitin‐1 (PHB, also known as PHB1), a member of the Band‐7 family of proteins, is highly conserved evolutionarily, widely expressed, and present in different cellular compartments. Genetic studies with different organism models have provided strong evidence for an important biological role of PHB in mitochondrial function, cell proliferation, and ...
Suresh, Mishra +2 more
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Microbiology Spectrum, 2023 Theileriosis is a tick-borne disease caused by Theileria annulata, an intracellular parasite that belongs to the phylum Apicomplexa. The infective forms of the parasite to cattle are sporozoites that are introduced into the host when the infected ticks ...
Prasanna Babu Araveti +5 more
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Expression and co-location of prohibitin genes in salt-tolerance QTLs in rice (Oryza sativa)
The Indian Journal of Agricultural Sciences, 2020 Prohibitin proteins are involved in diverse biological functions including cell cycle regulation, mitochondrial activity, apoptosis, hormonal signalling and so on.
Rakesh Bhowmick +3 more
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Mitochondrial Disruption by Amyloid Beta 42 Identified by Proteomics and Pathway Mapping
Cells, 2021 Alzheimer’s disease (AD) is marked by chronic neurodegeneration associated with the occurrence of plaques containing amyloid β (Aβ) proteins in various parts of the human brain.
Patricia Sinclair +2 more
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