An Unusual Prohibitin Regulates Malaria Parasite Mitochondrial Membrane Potential [PDF]
Cell Reports, 2018 Summary: Proteins of the stomatin/prohibitin/flotillin/HfIK/C (SPFH) family are membrane-anchored and perform diverse cellular functions in different organelles.
Joachim Michael Matz +3 more
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Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells [PDF]
Nature Communications, 2021 Prohibitin 2 can localize to the axon-Schwann-cell interface and is required for myelin formation. Here, the authors show that deletion of prohibitin 1 in Schwann cells instead triggers severe myelin loss likely caused by mitochondrial dysfunction, and ...
Gustavo Della-Flora Nunes +10 more
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Prohibitin Is Involved in Patients with IgG4 Related Disease. [PDF]
PLoS ONE, 2015 IgG4-related disease (IgG4-RD) is a chronic systemic disease involved in many organs and tissues. As only limited autoantigens have been found since the beginning of this century, the aim of this study was to reveal new candidate autoantigens of IgG4-RD ...
Hongwu Du +8 more
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Recent advances in pancreatic β-cell dysfunction in type 2 diabetes mellitus: Intracellular stress and dedifferentiation. [PDF]
J Diabetes InvestigJournal of Diabetes Investigation, Volume 17, Issue 8, Page 1254-1256, August 2026.
Kido N, Asahara SI.
europepmc +2 more sources
Scalable discovery of homomeric protein-protein interactions from cross-linking mass spectrometry data with CLAUDIO 2.0. [PDF]
Protein SciAbstract Cross‐linking mass spectrometry (XL‐MS) is a powerful biochemical approach for residue‐level characterization of protein structures and interactions under near‐native conditions. The growing scale of XL‐MS datasets demands scalable analysis pipelines that capture signals often overlooked in conventional workflows, including homomeric ...
Löser T +5 more
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In situ architecture of the human prohibitin complex. [PDF]
Nat Cell BiolProhibitins are a highly conserved family of proteins that have been implicated in a variety of functions including mitochondrial stress signalling and housekeeping, cell cycle progression, apoptosis, lifespan regulation and many others.
Lange F +7 more
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Exploring thylakoid emergence: evolution of membrane biogenesis and photosystem II assembly in early-diverging cyanobacteria. [PDF]
New PhytolOverview of the results. Phylogenetic analyses of 36 assembly factors of photosystem II (PSII) and 13 proteins involved in membrane dynamics summarized in Siebenaller & Schneider (2023) were performed to investigate the taxonomic distributions and structural differences between the thylakoid‐less Gloeobacterales and the Phycobacteria. Summary Thylakoid
Hambücken L, Baurain D, Cornet L.
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Protein Profile of Multiple Myeloma-Derived Extracellular Vesicles for the Discovery of Novel Myeloma-Related Biomarkers. [PDF]
Cancer SciComparison of extracellular vesicles with parental cells through proteomic profiling, followed by an integrated bioinformatic pipeline including disease association and transcriptomic analyses, identifies candidate biomarkers for multiple myeloma. Among these, MIF emerges as a clinically relevant marker, supported by validation in patient samples and ...
Platonova N +13 more
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Prohibitin 1 in liver injury and cancer [PDF]
, 2020 UNLABELLED: Prohibitin 1 is an evolutionary conserved and ubiquitously expressed protein that exerts different biological functions depending on its subcellular localization.
Barbier-Torres, Lucía, Lu, Shelly C
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Microbiology Spectrum, 2023 Theileriosis is a tick-borne disease caused by Theileria annulata, an intracellular parasite that belongs to the phylum Apicomplexa. The infective forms of the parasite to cattle are sporozoites that are introduced into the host when the infected ticks ...
Prasanna Babu Araveti +5 more
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