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Increasing cases related to the pathogenicity of Enterovirus D68 (EV-D68) have made it a growing worldwide public health concern, especially due to increased severe respiratory illness and acute flaccid myelitis (AFM) in children.
Jinyu Li +12 more
doaj +1 more source
At the crossway of
Immune cells detect specific microbes or damage to tissue integrity in order to initiate efficient immune responses. Abnormal accumulation of proteins in the endoplasmic reticulum (ER) can be seen as a sign of cellular malfunction and stress that triggers a collection of conserved emergency rescue programs.
Reverendo, Marisa +4 more
openaire +5 more sources
In 2009, a novel H1N1 influenza virus caused the first influenza pandemic of the 21st century. Studies have shown that the influenza M gene played important roles in the pathogenicity and transmissibility of the 2009 H1N1 pandemic ((H1N1)pdm09), whilst ...
Rujuan Wu +11 more
doaj +1 more source
Neutrophil-Mediated Inhibition of Proinflammatory Cytokine Responses [PDF]
Abstract Neutrophils (polymorphonuclear neutrophils [PMNs]) play an elaborate role in the innate immune response against invading pathogens. Recent research provided evidence that PMNs can play a modulatory role in inflammation next to their primary role of phagocytosis.
Gresnigt, M.S. +6 more
openaire +3 more sources
Whether the interaction between the gut microbiota and the immune response influences the evolution of cirrhosis is poorly understood. We aimed to investigate modifications of the microbiome and the immune response during the progression of cirrhosis ...
Alba Santiago +12 more
doaj +3 more sources
Aggregatibacter actinomycetemcomitans has been described as a member of the indigenous oral microbiota of humans, and is involved in the pathology of periodontitis and various non-oral infections. This bacterium selectively kills human leukocytes through
Anders Johansson
doaj +3 more sources
Effect of BCG vaccination on proinflammatory responses in elderly individuals [PDF]
BCG vaccination significantly diminished proinflammatory responses in elderly individuals in COVID-19 hot spots.
Nathella Pavan Kumar +8 more
openaire +3 more sources
Photoperiodic regulation of behavioral responsiveness to proinflammatory cytokines [PDF]
Symptoms of bacterial infection include decreases in body mass (cachexia), induction of depressive-like hedonic tone (anhedonia), decreases in food intake (anorexia), and increases in body temperature (fever). Recognition of bacteria by the innate immune system triggers the release of proinflammatory cytokines which induce these sickness behaviors via ...
Jarvi C, Wen, Brian J, Prendergast
openaire +2 more sources
Both influenza A virus (IAV) and influenza D virus (IDV) are enzootic in pigs. IAV causes approximately 100% morbidity with low mortality, whereas IDV leads to only mild respiratory diseases in pigs.
Minhui Guan +10 more
doaj +1 more source
CITED2 Restrains Proinflammatory Macrophage Activation and Response [PDF]
Macrophages are strategically distributed in mammalian tissues and play an essential role in priming the immune response. However, macrophages need to constantly strike a balance between activation and inhibition states to avoid a futile inflammatory reaction.
Gun-Dong, Kim +7 more
openaire +2 more sources

