Results 21 to 30 of about 5,465,036 (281)

Transcriptomic Profiling Reveals a Role for TREM-1 Activation in Enterovirus D68 Infection-Induced Proinflammatory Responses

open access: yesFrontiers in Immunology, 2021
Increasing cases related to the pathogenicity of Enterovirus D68 (EV-D68) have made it a growing worldwide public health concern, especially due to increased severe respiratory illness and acute flaccid myelitis (AFM) in children.
Jinyu Li   +12 more
doaj   +1 more source

At the crossway of ER‐stress and proinflammatory responses [PDF]

open access: yesThe FEBS Journal, 2018
Immune cells detect specific microbes or damage to tissue integrity in order to initiate efficient immune responses. Abnormal accumulation of proteins in the endoplasmic reticulum (ER) can be seen as a sign of cellular malfunction and stress that triggers a collection of conserved emergency rescue programs.
Reverendo, Marisa   +4 more
openaire   +5 more sources

The Mobility of Eurasian Avian-like M2 Is Determined by Residue E79 Which Is Essential for Pathogenicity of 2009 Pandemic H1N1 Influenza Virus in Mice

open access: yesViruses, 2023
In 2009, a novel H1N1 influenza virus caused the first influenza pandemic of the 21st century. Studies have shown that the influenza M gene played important roles in the pathogenicity and transmissibility of the 2009 H1N1 pandemic ((H1N1)pdm09), whilst ...
Rujuan Wu   +11 more
doaj   +1 more source

Neutrophil-Mediated Inhibition of Proinflammatory Cytokine Responses [PDF]

open access: yesThe Journal of Immunology, 2012
Abstract Neutrophils (polymorphonuclear neutrophils [PMNs]) play an elaborate role in the innate immune response against invading pathogens. Recent research provided evidence that PMNs can play a modulatory role in inflammation next to their primary role of phagocytosis.
Gresnigt, M.S.   +6 more
openaire   +3 more sources

Sequential Changes in the Mesenteric Lymph Node Microbiome and Immune Response during Cirrhosis Induction in Rats

open access: yesmSystems, 2019
Whether the interaction between the gut microbiota and the immune response influences the evolution of cirrhosis is poorly understood. We aimed to investigate modifications of the microbiome and the immune response during the progression of cirrhosis ...
Alba Santiago   +12 more
doaj   +3 more sources

Aggregatibacter actinomycetemcomitans Leukotoxin: A Powerful Tool with Capacity to Cause Imbalance in the Host Inflammatory Response

open access: yesToxins, 2011
Aggregatibacter actinomycetemcomitans has been described as a member of the indigenous oral microbiota of humans, and is involved in the pathology of periodontitis and various non-oral infections. This bacterium selectively kills human leukocytes through
Anders Johansson
doaj   +3 more sources

Effect of BCG vaccination on proinflammatory responses in elderly individuals [PDF]

open access: yesScience Advances, 2021
BCG vaccination significantly diminished proinflammatory responses in elderly individuals in COVID-19 hot spots.
Nathella Pavan Kumar   +8 more
openaire   +3 more sources

Photoperiodic regulation of behavioral responsiveness to proinflammatory cytokines [PDF]

open access: yesPhysiology & Behavior, 2007
Symptoms of bacterial infection include decreases in body mass (cachexia), induction of depressive-like hedonic tone (anhedonia), decreases in food intake (anorexia), and increases in body temperature (fever). Recognition of bacteria by the innate immune system triggers the release of proinflammatory cytokines which induce these sickness behaviors via ...
Jarvi C, Wen, Brian J, Prendergast
openaire   +2 more sources

Time-Dependent Proinflammatory Responses Shape Virus Interference during Coinfections of Influenza A Virus and Influenza D Virus

open access: yesViruses, 2022
Both influenza A virus (IAV) and influenza D virus (IDV) are enzootic in pigs. IAV causes approximately 100% morbidity with low mortality, whereas IDV leads to only mild respiratory diseases in pigs.
Minhui Guan   +10 more
doaj   +1 more source

CITED2 Restrains Proinflammatory Macrophage Activation and Response [PDF]

open access: yesMolecular and Cellular Biology, 2018
Macrophages are strategically distributed in mammalian tissues and play an essential role in priming the immune response. However, macrophages need to constantly strike a balance between activation and inhibition states to avoid a futile inflammatory reaction.
Gun-Dong, Kim   +7 more
openaire   +2 more sources

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